在调节不同的细胞通路的小分子RNA有牵连。
MicroRNAs have been implicated in regulating diverse cellular pathways.
但缺陷基因却不同产生蛋白质以维持线粒体的正常功能—尤其是神经系统细胞通路的线粒体。
But a defect in the gene may disable its proteins from performing their normal functions in mitochondria - most notably the mitochondria within the nervous system's cellular pathways.
这些观察提示突变的酪氨酸磷酸酶是肿瘤抑制基因,它调节的细胞通路可能会被利用到治疗干预中去。
These observations suggest that the mutated tyrosine phosphatases are tumor suppressor genes, regulating cellular pathways that may be amenable to therapeutic intervention.
当推敲人员把不含细胞通路的尼古丁用于白鼠时,这种尼古丁就不再像凡是的尼古丁,丢失了其使白鼠减肥的功能。发现。
When they gaudio-videoe nicotine to mice without that cellular pathway it didn't help them lose weight like it did normal mice.
这些泵结构和通路跟每个人体细胞一样使用了同一种燃料:三磷酸腺苷,或atp。
The pumps and channels are powered by the same fuel that drives every human cell: adenosine triphosphate, or ATP.
然后,当研究人员给小鼠注射一种药物,衰老细胞的死亡通路会则被激活。
Then, when the researchers gave the mice a drug, the death pathway would be activated in all senescent cells.
肿瘤药物主要是通过抑制一种下调通路,从而简介导致细胞死亡。
Oncology drugs act primarily by inhibiting a deregulated pathway, which indirectly leads to cell death.
跟踪一个细胞到另一个细胞的神经通路也是可能的。
It is also possible to trace neural pathways from cell to cell.
红外线使窝器膜组织升温,当达到阈值后TRPA 1通路打开,离子流入神经细胞并催发电信号。
Infrared radiation heats up the pit membrane tissue, and TRPA1 channels open when a threshold temperature is reached, allowing ions to flow into the nerve cells and triggering an electrical signal.
另外的靶向治疗在于能干扰肺癌细胞繁殖过程中的信号通路。
Other targeted therapies interrupt the signals that cause lung cancer cells to multiply, as shown in the highly magnified image here.
在肿瘤药物治疗中,首次把目标放在调节导致疾病的细胞信号通路。
It was first in oncology that therapy was aimed at the deregulated cell signaling that leads to the disease.
然而,许多人类疾病(包括癌症)的细胞信号通路发生错误。
However, in a number of human diseases, including cancer, cell signaling pathways can go awry.
显示出的是与损伤后T细胞功能紊乱相关的成百上千的基因和蛋白的功能图,以及它们在信号通路中的配体。
What emerged was a map of the likely functions of hundreds of genes and proteins related to T cell post-trauma dysfunction, and their likely partners in signaling pathways.
为了进一步提高该生物学过程的效率,该团队决定在另一自然通路上着手—细胞存活通路。
Attempting to increase the efficiency of the process even further, the team decided to enlist another natural pathway, the cell survival pathway.
调节干细胞功能的通路在癌中通常是衰减的。
Pathways that govern stem cell (SC) function are often subverted in cancer.
这些改变被定义为一组12个核心的细胞信号通路和过程,每个通路在肿瘤有67%到100%的改变。
These alterations defined a core set of 12 cellular signaling pathways and processes that were each genetically altered in 67% to 100% of the tumors.
新的研究发现了一种通过操纵宿主细胞内的一种常见信号通路来破坏早期宿主免疫反应并提高致病性的以前未知的酶反应机制。
New research identifies a previously unknown enzymatic mechanism that subverts the early host immune response and promotes pathogenicity by manipulating a common signaling pathway in host cells.
现对尼古丁调控细胞凋亡相关的各种信号通路及其分子机制进行综述。
This paper mainly reviews the signal pathways and molecular mechanisms of nicotine in apoptotic regulation.
这项研究说明了EGFR–SGLT1通路通过维持细胞内的葡萄糖水平,阻止自噬性细胞死亡,从而为肿瘤细胞提供了生存优势。
This study reveals that EGFR–SGLT1 may confer a survival advantage to cancer cells by maintaining a basal level of intracellular glucose and preventing autophagy.
在任一点阻断这条通路,或者沉默与炎症小体形成相关的基因或者编码半胱天冬酶- 1的基因,都能导致细胞死亡数目增加。
Interrupting the pathway at any point, either by silencing the genes responsible for the inflammasome formation or the gene for caspase-1, resulted in increased cell death.
耐药细胞与敏感细胞相比igf2的表达更多,抑制IGF通路能恢复肿瘤细胞对紫杉醇的敏感性。
Resistant cells had higher IGF2 expression compared with sensitive cells, and IGF pathway inhibition restored sensitivity to Taxol.
本文就UA对肿瘤细胞增殖信号通路的影响和抗心血管疾病作用研究进展方面进行综述,以期为UA的开发提供新思路。
This article reviews effects of UA on cancer cell proliferation signal transduction pathway and anti-vascular disease in order to provide some new ideas on the development of UA.
通过应用PPAR,他们能够绕过损伤的胰岛素信号通路,使得需要胰岛素的细胞得以存活。
However, by administering PPAR, they were able to bypass the defects in insulin signaling and preserve the cells that need insulin to thrive.
结论:针刺能刺激大鼠胃黏膜细胞信号转导通路中蛋白激酶c的活化,并且存在经脉-脏腑的特异性联系。
CONCLUSION: the acupuncture can stimulate the activation of PKC in gastric mucous cell signal conductive pathway of rats, and there is a special correlation between meridian and internal organs.
但是巨噬细胞的信号通路中也包括SNAP - 25,因此查普曼博士想,他能够用肉毒素来关闭这些免疫细胞。
But macrophage signalling also involves SNAP-25, so Dr Chapman thinks he can use botulinum toxin to shut the cells up.
个别重点控制淋巴细胞激活的信号通路的组成部分,也已确定。
Key individual components of signaling pathways that control lymphocyte activation have been identified.
个别重点控制淋巴细胞激活的信号通路的组成部分,也已确定。
Key individual components of signaling pathways that control lymphocyte activation have been identified.
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