目的探讨在大鼠胰腺移植急性排斥反应中调节激活正常T细胞表达和分泌因子(RANTES)的作用。
Objective To investigate the role of regulated upon activation, normal t cell expressed and secreted (RANTES) in the acute pancreatic allograft rejection in rats.
研究表明，组蛋白的乙酰化与去乙酰化状态，可作用于T、B细胞的发育、分化、成熟、分泌及表面因子的表达等多个方面。
Studies had shown that acetylation and deacetylation of histone are of certain value on t, B cell's development, differentiation, maturation, secretion and surface factor's expression etc.
紫外线作用于成纤维细胞，引起细胞因子分泌及基因表达的改变，不仅能造成真皮层的损伤，还可被用来治疗某些疾病，如局限性硬皮病。
Ultraviolet not only causes dermal damages by changing cytokine secretion and gene expression of human skin fibroblasts, but also is used to treat some diseases such as localized scleroderma.
肿瘤细胞高表达生长因子和神经节苷脂，并将生长因子分泌到或将神经节苷脂脱落于肿瘤细胞周围的微环境中。
Growth factors and gangliosides are highly expressed in tumor cells, and secreted and shedded into the microenvironment of tumor cells respectively.
结论：MMP - 2表达增加可能受到源自口腔癌相关成纤维细胞可溶性因子的旁分泌介导，而MMP - 9表达可能需要口腔癌细胞与癌相关成纤维细胞的直接接触。
Conclusion: It was suggested that MMP-2 expression is increased by paracrine stimulation mediated by soluble factors originated from oral CAFs and MMP-9 expression requires direct cell-cell contact.
目前认为KSHV - MCD所表达的病毒裂解蛋白参与了细胞因子调节异常、旁分泌信号传导和疾病的发生。
It is thought that viral lytic proteins expressed in KSHV-MCD contribute to cytokine dysregulation, paracrine signaling, and the pathogenesis of this disease.
基质细胞与细胞外基质协同作用，并通过分泌众多细胞因子和表达多种粘附因子形成了一个调控造血细胞增殖和分化的网络体系。
Bone marrow stroma cells function cooperating with their surrounding ECM form a complicate network regulating differentiation and proliferation of hematopoietic progenitor cells.
PGE2自分泌的方式运作配合旁分泌的IL - 1信号诱发间充质干细胞大量细胞因子的表达。
The resulting PGE2 operates in an autocrine manner, cooperating with ongoing paracrine IL-1 signaling, to induce expression of a group of cytokines by the MSCs.
结论：稳定表达人ox40l的乳腺癌转基因细胞在体外能有效地活化t细胞，介导其增殖、分泌细胞因子及抑制T细胞活化诱导的细胞死亡。
CONCLUSION: OX40L-MDA-MB-435 cells could activate t cells in vitro, promote t cell proliferation and cytokine secretion, and suppress t cell activation-induced cell death.
结论：稳定表达人ox40l的乳腺癌转基因细胞在体外能有效地活化t细胞，介导其增殖、分泌细胞因子及抑制T细胞活化诱导的细胞死亡。
CONCLUSION: OX40L-MDA-MB-435 cells could activate t cells in vitro, promote t cell proliferation and cytokine secretion, and suppress t cell activation-induced cell death.
应用推荐