它们位于血管网周围,可以起到抗原递呈细胞的作用。抗原递呈细胞启动针对抗原的免疫反应并释放入血。
They are found in a perivascular network and may serve as the antigen presenting cell which initiates immune responses to antigens delivered through the circulation.
我们知道,人体对外来抗原的免疫应答依赖t细胞和特异性抗原递呈细胞(APC)之间协调的相互作用。
It is generally accepted that normal immune response to extrinsic antigens depends on coordinating interaction between t cells and antigen presenting cells (APCs).
在辅助T细胞激发针对病原的免疫反应之前,它必须感觉到位于抗原递呈细胞面表的入侵者分子片段。
Before a helper t cell can trigger a response to a pathogen or parasite, it has to "feel" these molecular bits of an invader displayed on the surface of an antigen-presenting cell (APC).
树状突细胞(DC)具有强大的抗原递呈能力,并能有效激发T细胞应答,是目前抗肿瘤免疫治疗研究的热点之一。
It has been proved that Dendritic cells (DCs) have strongly ability to present antigen. DCs can trigger t cell responses and enhance the t cell mediated anti tumor effect.
第一信号为抗原与T细胞受体TCR的结合,第二信号为抗原递呈细胞上的协同刺激分子与T、B淋巴细胞上的受体结合。
The first signal is the binding of antigen with TCR on T cells. The second signal is the binding of co-stimulate on the APC with their receptors presenting on T and B lymphocytes.
因此,树突状细胞(DC细胞)递呈肿瘤抗原给共培养的CIK细胞,希望可以增强CIK细胞识别肿瘤的能力以及提高其肿瘤杀伤活性。
Hence, dendritic cells (DC) were cultured and engineered to present tumor antigens to CIK cells hoping that this might enhance the recognition of tumor cells and its subsequent killing.
树突状细胞是目前发现的抗原递呈功能最强的专职抗原递呈细胞,也是唯一能够激活初始免疫应答的APC,在对肿瘤产生主动免疫上起着重要的作用。
Dendritic cells is a function of the recursive antigen found most full-time antigen oral cells, also can activate the immune response, the initial APC on immunization tumors plays an important role.
树突状细胞是目前发现的抗原递呈功能最强的专职抗原递呈细胞,也是唯一能够激活初始免疫应答的APC,在对肿瘤产生主动免疫上起着重要的作用。
Dendritic cells is a function of the recursive antigen found most full-time antigen oral cells, also can activate the immune response, the initial APC on immunization tumors plays an important role.
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