结论雄黄可以逆转MCF7/ADM细胞的多药耐药性,并呈剂量依赖性;
Realgar can down regulate the expression of mdrl. mrp and bcrp in MCF 7/ADM cells.
近年研究发现容积调控性氯通道与肿瘤细胞的增殖、侵袭、迁移、凋亡及多药耐药性等恶性生物学行为有关。
In recent years, it has been realized that volume-regulated chloride channels are closely associated with proliferation, invasion, migration, apoptosis and multi drug resistance of tumor cells.
采用流式细胞术检测骨髓细胞多药耐药蛋白P170的相对表达率,并分析P170表达阳性率与耐药性和性别间的关系。
The expression of multidrug resistance protein P170 in marrow cells was detected by flow cytometry, and the correlations of the expression of P170 with drug resistance and gender were analysed.
目的:研究卡维地洛对人膀胱癌耐药细胞株BIU-87/ADM的多药耐药性逆转作用。
Purpose:To study the reversal effects on multidrug resistance in multidrug-resistent bladder cell lines BIU-87/ADM.
结论5 F 11 -DXR对敏感靶细胞的杀伤作用较d XR明显增强,并可有效逆转耐药靶细胞对DXR的多药耐药性。
Conclusion 5f11-dxr can remarkably increase the cytotoxicity of DXR to the sensitive target cells and even effectively reverse the drug-resistant cell lines to DXR.
目的探讨金克-槐耳颗粒是否能逆转人乳腺癌MCF-7/A细胞对阿霉素(ADM)的多药耐药性(MDR)及其逆转机制。
Objective The aim of this study is to discuss whether the Jinke plaster can reverse the MDR of the breast cancer cell strian MCF-7/A to ADM or not and the mechanism.
两株耐药细胞对5-氟尿嘧啶、甲氨蝶呤产生了耐药,具有多药耐药性的特点;
Two cell lines with the characteristics of multi-drug resistance resistant to 5-fluorouracil and methotrexate;
两株耐药细胞对5-氟尿嘧啶、甲氨蝶呤产生了耐药,具有多药耐药性的特点;
Two cell lines with the characteristics of multi-drug resistance resistant to 5-fluorouracil and methotrexate;
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