结论雄黄可以逆转MCF7/ADM细胞的多药耐药性，并呈剂量依赖性；
Realgar can down regulate the expression of mdrl. mrp and bcrp in MCF 7/ADM cells.
依赖于半胱氨酸蛋白酶的激活，美沙酮通过激活线粒体克服了白血病细胞中的阿霉素耐药、多药耐药、和凋亡抑制。
Depending on caspase activation, methadone overcomes doxorubicin resistance, multidrug resistance, and apoptosis resistance in leukemia cells through activation of mitochondria.
目的研究川芎嗪脂质体在体外对肿瘤细胞的细胞毒作用和对多药耐药的逆转作用，并研究脂质体剂型对上述作用的影响。
Objective: to study the cytotoxic effect of ligustrazine liposomes on tumor cell in vitro and the reversing effect on the MDR, and explore the influence of dosage form on the above effects.
近年研究发现容积调控性氯通道与肿瘤细胞的增殖、侵袭、迁移、凋亡及多药耐药性等恶性生物学行为有关。
In recent years, it has been realized that volume-regulated chloride channels are closely associated with proliferation, invasion, migration, apoptosis and multi drug resistance of tumor cells.
目的探讨人肺癌细胞株对化疗药物的敏感性与多药耐药相关基因和凋亡调控基因表达的关系。
Objective To explore the relationship of chemotherapy sensitivity and expression of multidrug resistance genes and apoptosis regulation genes in human lung cancer cell lines.
目的探讨流式细胞术在阿霉素多药耐药研究中的特殊意义。
Objective to evaluate the significance of flow cytometry (FCM) in the analysis of multi drug resistance of doxorubicin.
目前的研究发现，有多类细胞色素P 450酶与肿瘤多药耐药的发生密切相关。
In recent years, researches found that there were many kinds of cytochrome P450 enzymes which related to multidrug resistance of tumor.
目的探讨人乳腺癌细胞化疗敏感性与多药耐药相关基因和凋亡调控基因表达的关系。
Objective To explore the relationship of chemotherapy sensitivity and expression of multidrug resistance genes and apoptosis regulation genes in human breast cancer cell lines.
目的通过检测儿童急性白血病多药耐药基因及细胞凋亡调控基因表达水平的改变，分析不同类型白血病的主要耐药机制。
Objective To study the drug resistance in different types of acute leukemia in children, the expression of multidrug resistance gene and apoptosis-related genes were analyzed.
目的：研究粉防己碱与长春新碱合用能否逆转人乳腺癌M CF 7多药耐药细胞的抗凋亡作用。
Objective: to study whether the anti-apoptotic action is reversed by tetrandrine in a combination with vincristine in human breast carcinoma MCF-7 multidrug-resistant cells.
目的探讨锌带基因ZNRD1在多药耐药胃癌细胞中的表达和作用。
Objective To study the expression and function of zinc ribbon gene ZNRD1 in drug resistant cells of gastric cancer.
目的探讨CYP3A5基因与白血病细胞多药耐药的关系。
Objective To investigate if CYP3A5 gene is involved in the molecular mechanisms for multiple drug resistance in leukemia cells.
目的：研究瑞香狼毒（SC）小鼠药物血清与细胞毒化疗药物联合应用对K5 6 2 /VCR多药耐药细胞的协同抗肿瘤效应。
Objective:To study the synergistic antitumor effects of Stellera chamaejasme (SC) with cytotoxic chemotherapeutic agents on K562/VCR multi-drug resistance (MDR) cells.
采用流式细胞术检测骨髓细胞多药耐药蛋白P170的相对表达率，并分析P170表达阳性率与耐药性和性别间的关系。
The expression of multidrug resistance protein P170 in marrow cells was detected by flow cytometry, and the correlations of the expression of P170 with drug resistance and gender were analysed.
通过腺病毒载体介导使多药耐药基因转染入脐血有核细胞，提高其对化疗药物的耐受性。
MDR1 gene was transfered to cord blood nucleate cells (CBNC) mediated by adenovirus vector, for enhancing its resistance to chemotherapeutic drugs.
结论：基因转染法是建立人膀胱癌多药耐药细胞模型的理想方法。
Conclusion: The establishment of MDR cell lines by gene transfection is an ideal method.
目的：建立人舌鳞状细胞癌耐放疗细胞系并检测多药耐药基因和蛋白的表达。
Objective: To establish a radiation-resistant human tongue squamous carcinoma cell line and to detect the expression of multidrug-resistant gene( MDR1) and protein (P-gp).
逆转肿瘤细胞多药耐药旨在全部或部分恢复肿瘤细胞对化疗药物的敏感性，已成为肿瘤mdr研究的热点。
The aim of reversing MDR of gastric cancer cells is to entirely or partly recovery their chemotherapy to drugs, which has become a hot spot in solid tumor MDR research nowadays.
目的：研究卡维地洛对人膀胱癌耐药细胞株BIU-87/ADM的多药耐药性逆转作用。
Purpose:To study the reversal effects on multidrug resistance in multidrug-resistent bladder cell lines BIU-87/ADM.
目的：制备MRK - 16修饰免疫脂质体，并检测免疫脂质体对非小细胞肺癌多药耐药细胞的杀伤及多药耐药逆转作用。
Objective: To determine the reversion of MDR of human lung carcinoma by ADM liposomes and ADM immunoliposomes modified by MRK-16 in vitro.
结论5 F 11 -DXR对敏感靶细胞的杀伤作用较d XR明显增强，并可有效逆转耐药靶细胞对DXR的多药耐药性。
Conclusion 5f11-dxr can remarkably increase the cytotoxicity of DXR to the sensitive target cells and even effectively reverse the drug-resistant cell lines to DXR.
临床化疗失败的重要原因是肿瘤细胞对化疗药物产生多药耐药（MDR）。
Multidrug resistance to chemotherapeutic drugs is an important reason for clinical chemotherapy failure.
目的探讨金克-槐耳颗粒是否能逆转人乳腺癌MCF-7/A细胞对阿霉素（ADM）的多药耐药性（MDR）及其逆转机制。
Objective The aim of this study is to discuss whether the Jinke plaster can reverse the MDR of the breast cancer cell strian MCF-7/A to ADM or not and the mechanism.
两株耐药细胞对5-氟尿嘧啶、甲氨蝶呤产生了耐药，具有多药耐药性的特点；
Two cell lines with the characteristics of multi-drug resistance resistant to 5-fluorouracil and methotrexate;
现有研究表明，肺癌细胞多药耐药造成的化疗失败是影响患者生存率的主要原因。
It has been proven that chemotherapy failure caused by multidrug resistance in lung tumor cells is the main cause for the patient's survival rate.
现有研究表明，肺癌细胞多药耐药造成的化疗失败是影响患者生存率的主要原因。
It has been proven that chemotherapy failure caused by multidrug resistance in lung tumor cells is the main cause for the patient's survival rate.
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