目的:观察小鼠骨髓形成肝细胞的基因表达谱的变化规律,研究骨髓形成肝细胞的分子机制。
Objective:To observe the change of gene expression profile while the mouse bone marrow cells forming liver cell and study the gene mechanism of bone marrow cells forming liver cells.
方法利用低密度脂蛋白作用人血管内皮细胞系ecv304,通过基因芯片分析人信号传导相关蛋白的表达谱。
Methods Microarray analysis on human signal transduction associated proteins was applied to profile changes in gene expression of human ECV304 endothelial cells induced by low density lipoprotein.
目的利用已经建立的胶质瘤细胞诱导分化相关基因表达谱,筛选胶质瘤恶性进展相关基因。
Objective To screen out genes associated with malignant progression of glioma, based on the established glioma cell differentiation-inducing gene expression profiles.
目的比较不同转移潜能人肝癌细胞系的基因表达谱,寻找与癌转移相关的基因表达改变。
Objective to compare gene expression profile of human hepatocellular carcinoma (HCC) cell lines with different metastatic potentials, so as to screen for metastasis-related genes.
结论:交叉性别骨髓移植小鼠肝脏的基因表达谱变化规律为进一步研究骨髓形成肝细胞的分子机制奠定了实验基础。
Conclusion: the gene expression profile of bone marrow transplantation model have established a foundation to study the gene mechanism of bone marrow cells forming liver cells.
基因芯片技术是一种高通量的研究手段,可以在同一时刻对成千上万个基因的表达情况进行分析,形成完整的细胞基因表达谱。
DNA microarray technology is a high throughout method that can analyze the expression of thousands of genes at the same time to form a complete cellular gene expression profile.
目的利用基因表达谱芯片对NB 4细胞在硫化砷作用前后基因表达的差异性进行比较。
Objective To compare the gene expression status of NB4 cells before and after arsenic sulfide treatment by cDNA microarray.
目的用基因芯片技术研究高低转移人卵巢癌细胞系(HO 8910 PM和HO 8910)基因表达谱差异,筛选与转移相关的基因。
Objectives To study the difference between gene expressions of high (H0-8910PM) and low (HO-8910) metastatic human ovarian carcinoma cell lines and screen novel associated genes by cDNA microarray.
结论RAW264.7具有破骨细胞特征性基因表达谱,是一种较好的破骨前体细胞模型。
Conclusions RAW264. 7 cell could be used as a preferable preoste-oclast model in respect of its osteoclast characteristic gene expression profile.
目的:研究周期性牵张力对人成骨细胞基因表达谱的影响。
Objective: To study the effects of cyclic tensile stress on the gene expression profiles of human osteoblasts in vitro.
目的运用基因芯片技术研究人参总皂甙(TSPG)作用后K 562细胞基因表达谱的变化。
Objective to investigate the effect of the total saponin of Panax ginseng (TSPG) on gene expression profile of K562 cells using microarray technique.
目的利用基因表达谱芯片研究T淋巴细胞株(HUT78)在褪黑素作用后免疫相关基因表达的差异性。
Objective To in ve stigate the difference of immuno-related gene expressions in T lymphocyte line (HUT78) incubated with melatonin by cDNA microarray of gene expression profile.
通过分析酵母细胞的大规模基因表达谱数据,获得不同基因间表达的相关性。
Through seriate genome-wide mRNA expression data, similarity between two genes could be measured.
基因芯片技术建立颅内动脉瘤患者血液单核细胞基因表达谱,筛选与信号传导相关的基因表达情况。
To identify signal transduction-related genes in peripheral blood mononuclear cells from intracranial aneurysm patients using oligo-microarrays.
目的 :探讨葡萄胎与正常胎盘绒毛基因表达谱 ,研究葡萄胎滋养层细胞增生的机制。
OBJECTIVE:To explore gene expression profiles of complete hydatidiform mole to understand mechanisms of trophoblastic cell hyperplasia from gene level.
目的:运用芯片技术研究内源性一氧化碳(CO)刺激下血管平滑肌细胞凋亡相关基因表达谱的变化。
OBJECTIVE: to identify the gene expression profiles associated with the apoptosis of pulmonary arterial smooth muscle cells stimulated by carbon monoxide (CO).
目的观察人脐静脉内皮细胞株(ECV304细胞)在内皮抑素(es)作用前后基因表达谱的变化,并探讨其作用的分子机制。
Objective to observe the altered gene expression of ECV304 cell after treated with endostatin (es) using cDNA microarray, and to investigate its molecular mechanism.
此外,我们还应用基因芯片技术研究了SBP对肝细胞基因表达谱的影响。
Furthermore, microarray was used for studying the change of gene expression profiles of hepatocyte in addition of SBP1.
目的:研究视黄醇脱氢酶13 (Rdh13)基因在小鼠组织中的表达谱及其亚细胞定位,为其功能研究提供线索。
Objective: To study the expression profile of retinol dehydrogenase 13 (Rdh13) in mouse tissues and determine its subcellular localization.
目的:研究视黄醇脱氢酶13 (Rdh13)基因在小鼠组织中的表达谱及其亚细胞定位,为其功能研究提供线索。
Objective: To study the expression profile of retinol dehydrogenase 13 (Rdh13) in mouse tissues and determine its subcellular localization.
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