在实验室,他们用病毒感染那些细胞,这种病毒携带有能产生T细胞受体的基因,在这个例子中,实质上就是产生黑色素瘤导归器的基因。
In the lab, they infected those cells with a virus carrying genes that create T-cell receptors, essentially homing devices for, in this case, melanoma.
研究人员用一段被他们进行基因编码的基因重组病毒感染T细胞,这段基因编码是能够识别黑色素瘤细胞的受体蛋白的。
They did this by infecting the T-cells with genetically modified viruses carrying genes that coded for receptors to melanoma molecules.
活跃的巨细胞病毒和胶质母细胞瘤相联系的原因还不清楚。
Just why active cytomegalovirus is associated with glioblastoma is still unclear.
他们发现了在他们检查的罹患胶质母细胞瘤的病人当中有超过百分之九十的人的肿瘤中存在巨细胞病毒,但这种病毒并不存在于正常的脑组织或者是非恶性的脑肿瘤中。
They discovered cytomegalovirus in the tumours of more than 90% of those people with glioblastoma whom they examined, but not in healthy brain tissue, nor in non-malignant brain tumours.
该团队同样用改良的麻疹病毒感染髓母细胞瘤的鼠移植瘤模型,隔日注射一次,共10天。
The team also administered the modified measles virus to mouse models of medulloblastoma, administering treatment every other day for 10 days.
麻疹病毒可用于治疗髓母细胞瘤手术后瘤床的微残留的靶向治疗。
Measles virus therapy could be applied to the tumor bed following surgical resection to target microscopic residual disease.
我们的研究数据能够为进一步的麻疹病毒治疗髓母细胞瘤的临床研究提供依据。
These results provide initial data to be pursued with additional studies toward the goal of using the virus in a clinical trial for the treatment of medulloblastoma.
同时制备裸鼠u251细胞移植瘤模型并注射重组腺病毒,观察肿瘤生长情况。
The recombinant viruses were injected into the xenograft tumors of U251 cells in nude mice, then the tumor growth was observed.
天然的水泡性口膜炎病毒(VSV)是包括脑神经胶质瘤在内的多种肿瘤细胞的有力杀手,但也具有致命作用。
In its natural form, vesicular stomatitis virus (VSV) is a potent cancer-killer in a number of tumor cell types, including brain tumors called gliomas, but it can be lethal.
目的:探讨不同部位T细胞淋巴瘤(TML)与EB病毒(EBV)感染的关系。
Purpose To research the relation between EBV infection and T cell lymphoma(TML) from different sites of the body.
目的:研究广西地区鼻NK/T细胞淋巴瘤的临床病理特点及与EB病毒(EBV)的关系。
Objective:To detect the clinicopathologic features of nasal NK/T-cell lymphoma in Guangxi and their association with Epstein-Barr virus (EBV).
目的构建携带报告基因增强型绿色荧光蛋白(EGFP)的反转录病毒载体,并且探讨病毒载体对SK-N-SH神经母细胞瘤细胞株的感染效率。
Objective To construct the retroviral(RV) vector with report gene enhanced green fluorescent protein(EGFP) and to explore the gene transfection efficiency of RV on SK-N-SH neuroblastoma cells.
方法:将经新城疫病毒处理的小鼠肝癌细胞H 22为活瘤苗进行免疫接种。
Methods: mice were vaccinated with live tumor vaccine of NDV pretreated mice hepatic cancer cell H22.
Raffel医生说:“我们研究表明改良的麻疹病毒在治疗脑内的髓母细胞瘤方面显示很好的治疗潜力。”
"Our study demonstrates that a modified measles virus has therapeutic potential in the treatment of intracerebral medulloblastoma," said Dr. Raffel.
相比之下,溶瘤病毒就可以复制传播,理论上可以到达更多的肿瘤细胞。
In comparison, oncolytic viruses can replicate and spread and theoretically can efficiently reach more tumor cells.
马立克氏病病毒(MDV)是一种致t细胞瘤的疱疹病毒,然而病毒的致肿瘤机制仍不十分清楚。
Marek's disease virus (MDV) is a herpesvirus which induces the tumor of t cells in chickens. However its oncogenic mechanism is still unclear.
本文对人孔头瘤病毒及受感染细胞的超微结构进行了初步探讨。
The ultrastructure of HPV and the HPV infected cells were discussed.
由于几乎所有的髓母细胞瘤标本都表达麻疹病毒受体-CD46,所以麻疹病毒在治疗髓母细胞瘤上较其他病毒有明显的优势。
The fact that all of the surgical medulloblastoma specimens that we examined expressed the measles virus receptor leads us to believe that measles virus may have some advantages over other viruses.
结论:不同的肿瘤细胞对VSV病毒溶瘤的敏感性不同;
Conclusion: Different tumor cell lines showed different VSV oncolytic sensitivities;
结论:不同的肿瘤细胞对VSV病毒溶瘤的敏感性不同;
Conclusion: Different tumor cell lines showed different VSV oncolytic sensitivities;
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