研究中性彗星分析法检测肿瘤细胞内在放射敏感性的可靠性和影响因素。
Purpose]To investigate the reliability and the influencing factors of neutral comet assay in detecting the intrinsic radiosensitivity of tumor cells.
来自AT病人的细胞显示有缺陷的DNA损伤诱导检验点激活，对放射的敏感性和频率较高的染色体断裂(3,4)。
Cells from at patients display defective DNA damage-induced checkpoint activation, sensitivity to radiation, and a higher frequency of chromosome breakage (3, 4).
影响放射治疗效果的因素很多，其中肿瘤细胞内在的放射敏感性是关键因素之一。
Inherent radiosensitivity of tumor cell is one of critical factors among all kinds of the factors affecting the radiotherapy effect.
目的探讨A549肺腺癌多细胞球体放射抗拒细胞的化疗药物敏感性。
Objective To investigate the chemosensitivity of irradiated resistant cells of multicellular spheroids in A549 lung adenocarcinoma.
目的进一步证实人鼻咽癌细胞系cne 2z确实存在着放射敏感性的异质性，并探讨其有关机理。
Objective to further confirm that the human NPC cell line CNE-2Z indeed has radiosensitivity heterogeneity and to discuss its related mechanism.
结论人脑胶质瘤细胞具有不同的内在放射敏感性。
Conclusion The intrinsic radiosensitivity varies in different human glioma cells lines.
另外，研究发现，DNA修复系统的功能不仅是决定肿瘤细胞对化疗药物敏感性的重要因素，而且也直接影响到肿瘤细胞的放射敏感性。
In addition, it has been found that DNA repair system is not only associated with cellular sensitivity to chemotherapy, but also with cellular sensitivity to radiotherapy.
目的探讨肿瘤内毛细血管间距(ICD)和增殖细胞核抗原(pcna)与宫颈癌放射敏感性的关系。
Objective To investigate the correlationship between proliferating cell nuclear antigen (PCNA), intercapillary distance (ICD) and radiosensitivity in uterine cervical cancer.
集落形成法检测细胞存活曲线，反映放射敏感性变化；
Cell survival curves were determined by colony formation method to evaluate changes of radiosensitivity of the cells.
[目的]研究中性彗星分析法检测肿瘤细胞内在放射敏感性的可靠性和影响因素。
Purpose to investigate the reliability and the influencing factors of neutral comet assay in detecting the intrinsic radiosensitivity of tumor cells.
结论肺腺癌细胞的化疗耐药性与放射敏感性之间有一定的内在联系，化疗耐药性导致放疗敏感性降低。
ConclusionThere exists internal relations between the chemoresistance and radiosensitivity of lung adenocarcinoma cisplatin-resistant cell, chemo-resistance leads to reduced radiosensitivity.
目的筛选同一来源放射敏感性不同鼻咽癌细胞基因差异表达，探讨鼻咽癌放射抗拒机理。
Objective To observe the differential gene expression in human nasopharyngeal carcinoma (NPC) cell line with different radiosensitivity by cDNA microarray analysis.
目的：探讨直肠癌自发性细胞凋亡指数（SAI）、P5 3蛋白表达水平和放射敏感性的关系。
Objective:To investigate the correlation between the levels of the spontaneous apoptosis index(SAI), expressions of P53 and the radiosensitivity of rectal carcinoma.
目的：探讨调控Livin基因表达对食管癌ec9706细胞生长速度、细胞凋亡以及放射线敏感性的影响。
Aim: to observe the influence of regulating Livin gene expression on esophageal carcinoma cell line EC9706 growth, cell apoptosis and sensitivity to radioactive rays.
目的：探讨调控Livin基因表达对食管癌ec9706细胞生长速度、细胞凋亡以及放射线敏感性的影响。
Aim: to observe the influence of regulating Livin gene expression on esophageal carcinoma cell line EC9706 growth, cell apoptosis and sensitivity to radioactive rays.
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