本文用二步分段盐析法,制备了胎儿淋巴细胞抑制因子(FLIF)。
Fetal lymphocyte inhibitory factors (FLIF) are prepared by means of the successive two-step salting-out procedure using ammonium sulphate.
方法从培养的人胚肺成纤维细胞(WI- 38)中提取总rna,经rt -PCR获得人破骨细胞抑制因子基因。
METHODS Total RNA was extracted from human embryonic lung fibroblast cells (WI 38) and the whole length gene of human OPG was obtained by RT PCR.
在过去几年的研究中,抑制炎症因子(在免疫系统和神经系统都可找到的信号细胞)似乎能够减缓抑郁症的症状。
And in studies from the last few years, inhibiting inflammatory cytokines (signaling cells found in both the immune and nervous systems) seems to help alleviate depressive symptoms.
目的探讨巨噬细胞移动抑制因子在脓毒症小鼠心脏和肾组织中的表达规律。
Objective to investigate the expression profile of macrophage inhibitory factor in heart and renal tissues of sepsis mice.
胰岛素样生长因子系统在调节细胞增殖、分化与抑制凋亡中发挥重要作用。
Insulin-like growth factor (IGF) system plays an important role in regulating cell proliferation and differentiation, and inhibiting apoptosis.
结论:抑白血病因子具有抑制白血病细胞增殖和浸润的作用。
Conclusion: Anti leukemia factor have the effect of inhibitory proliferation and invasion to leukemia cell.
目前治疗胶质母细胞瘤的疗法直接采用抑制另一种细胞受体,即上皮生长因子受体(EGFR)。
Current therapies to treat glioblastomas are directed toward blocking the activity of another cellular receptor called epithelial growth factor receptor (EGFR).
众所周知,CCL5可激活细胞因子抑制艾滋病毒感染人体免疫细胞。
CCL5 is known to activate factors that suppress HIV infection of human immune cells.
本研究表明,干扰素可以通过抑制肿瘤依赖性转录因子的表达来达到抑制肿瘤的作用,这种转录因子可以调控肿瘤细胞的生长。
The present study indicates that interferon can suppress cancer growth by inhibiting expression of a cancer-dependent transcription factor that controls genes that regulate cancer cell growth.
类似的相反作用在其他肿瘤抑制因子中也有发现,但H - REV107 - 1的表达与非小细胞肺癌病人存活期的关联还是相当令人震惊。
Similar reverse functions have been identified for other tumor suppressors, but the correlation between H-REV107-1 expression and NSCLC patient survival is quite striking.
目的研究梅花鹿免疫细胞活性因子拮抗免疫抑制作用。
Objective to study on the antagonistic effect of sika deer immunologic cellular activity factor (DICAF) on immunosuppression.
这类生物碱的结构代表了潜在的抗炎特性----通过抑制与前炎细胞因子激活有关的因子发挥抗炎作用。
The study showed that forms of avenanthramides possess potential anti-inflammatory properties through inhibiting factors that are linked with activating proinflammatory cytokines.
结论:雷公藤红素对TNBS诱导的大鼠结肠炎具有显著保护作用,抑制促炎细胞因子的产生可能是其主要作用机制之一。
Conclusions: Tripterine has noticeable protective effects on TNBS-induced colitis in rats, suppression of proinflammatory cytokines may be one of its main mechanisms.
PF4属于造血负性调控因子,它抑制造血细胞增殖,但是它的这种作用是可逆的。
PF4 is a negative regulator of hematopoiesis and can inhibit hematopoietic cell proliferation but this effect is reversible.
结论含高剂量中药的大鼠血清有抑制血管内皮细胞生长因子诱导内皮细胞增殖的作用。
CONCLUSION the rat serum including high dose herb medicine could have an effect on inhibition of proliferation of endothelial cell induced by vascular ECGF.
目的:研究人骨肉瘤OS 732细胞系促血管生成作用及血管内皮生长因子(VEGF)抗体对其血管生成的抑制作用。
Purpose To study the angiogenesis induced by OS 732 cell line and its inhibition by anti VEGF antibody.
以血管内皮生长因子(VEGF)通路为靶点,抑制肾细胞癌血管生成,已成为肾细胞癌治疗的研究热点。
Therapy targeting for vascular endothelial growth factor (VEGF) signaling can inhibit angiogenesis of RCC, which is one of hot issues in RCC management.
结论:香桂丸可显著抑制异位内膜组织的生长,并对细胞因子有明显的调节作用。
Conclusion: Xianggui pill can restrain significantly the growth of allotopia intima tissue, and has apparently adjustment to the cytokine.
香桂丸可显著抑制异位内膜组织的生长,并对细胞因子有明显的调节作用。
Xianggui pill can restrain significantly the growth of allotopia intima tissue, and has apparently adjustment to the cytokine.
目的观察巨噬细胞移动抑制因子在大肠癌中的表达及其与细胞凋亡的关系。
Objective to observe the expression of macrophage migration inhibition factor (MIF) in colorectal carcinoma tissue and its correlation with cell apoptosis.
许多细胞外因子可以抑制中性粒细胞,但其具体机制尚不清楚。
Various extracellular factors can delay neutrophil apoptosis, but the molecular mechanisms are not dear completely.
本研究探讨骨髓内皮细胞分泌的造血抑制因子在扩增造血祖细胞中的作用并初步探讨其作用机制。
In this study, the roles of hematopoietic inhibitors elaborated by bone marrow endothelial cells in the proliferation and differentiation of hematopoietic progenitors were investigated.
结论:RSV对T细胞的免疫抑制作用,可能与其抑制T细胞的活化、增殖和细胞因子的分泌有关。
CONCLUSION: The immunosuppressive action of RSV may be related with its inhibitory effects on t cell activation, proliferation and cytokine expression.
目的:评价大黄素抗脑缺血损伤作用,并从细胞因子水平及表达方面探讨其抑制炎性级联反应机制。
Objective: to assess emodin antagonism to cerebral ischemia injury, and to discuss the mechanism of emodin inhibiting the inflammatory cascade reaction from the levels and expressions of cytokines.
结果表明OA护膝通过有效抑制细胞因子、调节MMP-3、HA的生物效应来延缓关节软骨的退变。
The results showed that OA kneepad could delay cataplasia of articular cartilage by inhibiting cytokines and adjusting biological effect of MMP-3, HA.
背景:基质细胞衍生因子是嗜淋巴细胞人类免疫缺陷病毒1感染的体外潜在抑制因子,可阻断人类免疫缺陷病毒1侵入人体的通路。
BACKGROUND: Stromal cell-derived factor 1 (SDF1), a potential inhibitor of infection by lymphophilic HIV-1 strains, can help to block the pathway of HIV-1 invasion into the human body.
为维持细胞在培养过程中的未分化状态,需要采用饲养层细胞培养,同时设计合理的培养液配方并添加多种抑制分化或促进增殖的细胞因子。
Feeder layer cells and suitable culture medium that supplemented with cytokines of promoting proliferation or restraining differentiation were crucial to keep chicken es in an undifferentiated state.
为维持细胞在培养过程中的未分化状态,需要采用饲养层细胞培养,同时设计合理的培养液配方并添加多种抑制分化或促进增殖的细胞因子。
Feeder layer cells and suitable culture medium that supplemented with cytokines of promoting proliferation or restraining differentiation were crucial to keep chicken es in an undifferentiated state.
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