未成熟T细胞通过TCR-CD3 复合物与自身抗原接合激活上述过程可能与克隆清除的形成机制及自我耐受有关。
Activation of this process in immature T cell by the bindng of the TCR CD3 to self antigens may therefor be the mechanism which produces clonal deletion and consequently self tolerance.
目的：探讨改善外周血来源的树突状细胞（DC）体外培养的方法，以促进DC的成熟并提高其递呈抗原和激发特异性免疫反应的能力。
PART I The Improvement of Dendritic Cell Culture Measures in vitroObjective: Improve the measures of dendritic cell culture in vitro, to increase the rate of mature and function of DC.
其能够抑制同种异体的T细胞的应答和修饰抗原呈递细胞的成熟。
They are able to suppress allogenic T-cell response and modify maturation of antigen-presenting cells.
本文从树突状细胞的来源、分化成熟、抗原提呈机理及抗肿瘤治疗的实验研究、临床应用等方面进行综述。
In this review, we summarize the source, differentiation, antigen presenting mechanism, the experimental and clinical researches on anti tumor therapy of dendritic cells.
细胞在成熟过程中通过T细胞表面受体基因重排，从而具有特异性识别抗原的能力，在这一过程中的任何失调都会导致疾病。
T cell receptor (TCR)gene rearrangement is an important event in T cell ontogeny that enables T cells to specifically recognise antigens, and any dysregulation in this process may result in diseases.
在捕获肿瘤抗原后，DC迁移至TDLN，发育成熟并递呈抗原，诱导T细胞分化、成熟，杀伤肿瘤细胞。
After capturing tumor antigen, DC migrates to TDLN where it becomes matured and starts presenting antigen, then induces t cell differentiation, maturation and to kill tumor cells.
目的探讨CD5 9抗原在血液系统恶性肿瘤患者红细胞及成熟粒细胞上的表达及意义。
Objective To explore the expression of CD59 antigen from patients with haematological malignancies and its clinical significance.
目的探讨CD5 9抗原在血液系统恶性肿瘤患者红细胞及成熟粒细胞上的表达及意义。
Objective To explore the expression of CD59 antigen from patients with haematological malignancies and its clinical significance.
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