当细胞积累了大量的错误折叠蛋白后,细胞的报警系统被打开,细胞应激应答被激活。
In response to the accumulation of misfolded proteins, the cellular alarm systems are switched on and stress responses are activated.
HSP70在细胞应激保护、热耐受、凋亡、炎症与免疫反应中均发挥其重要的生物学效应。
HSP70 plays a critical biological role in cells' stress protection, heat endurance, apoptosis, inflammation, and immunity reaction.
很多细胞活动会使T细胞应激产生淋巴因子,如中性粒细胞、巨噬细胞和淋巴细胞的吸附和活化。
Stimulated t cells produce lymphokines with a wide range of activities, such as attraction and activation of neutrophils, macrophages, and lymphocytes.
目的:探讨香烟提取物(CSE)对人支气管平滑肌细胞DNA损伤和细胞应激(热休克蛋白70表达)的影响。
AIM: To investigate DNA damage and cell stress (heat shock protein 70 expression) in human bronchi smooth muscle cells by cigarette smoke extract (CSE) in vitro.
我们对部分细胞周期、细胞凋亡、细胞应激与炎症反应相关基因进行了分析并用实时荧光定量pcr进行了验证,证实了基因芯片结果的可靠性。
We analyze some genes including cell cycle, apoptosis, stress and inflammation, which are confirmed by the real time RT-PCR, and the results are corresponded to that of cDNA microarray.
罗伯逊医生正在研究一种被称为抗氧化剂的分子,这种分子可能会保护细胞不受氧化应激的破坏。
Dr. Robertson is researching a molecule called antioxidants which might protect cells against damage from oxidative stress.
从用老鼠做的实验看来,吸烟之所以有抗过敏作用,是因为能够降低免疫细胞对过敏原的应激反应。
A study of mouse mast cells shows that cigarette smoke can prevent allergies by decreasing the reaction of immune cells to allergens.
海克米说:“人们之所以把自由基和衰老联系在一起,可能是因为自由基在线粒体(细胞的一部分)中产生是人体对衰老的应激反应。”
"Maybe the reason why free radicals and aging are correlated is because free radical production in the mitochondria (part of the cell) is a stress reaction to the damage of aging," Hekimi said.
他的细胞能量流失严重,尤其在脑细胞中,并且有严重氧化应激的迹象。
He had a profound loss of energy in his cells (particularly his brain cells), and indicators of severe oxidative stress.
由意大利和西班牙科学家们进行的这项研究显示,草莓能增强血红细胞的抗氧化应激能力。 氧化应激失调与多种疾病相关。
The study, carried out by Italian and Spanish researchers, showed that strawberries boost red blood cells' response to oxidative stress, an imbalance that is associated with various diseases.
研究人员目前正在研发一种新型化学物,可以阻止酶--11beta-HSD1 -- 生成,这种酶辅助细胞产生应激激素。
The researchers are currently investigating a new chemical compound which blocks an enzyme -- 11beta-HSD1 -- that is involved in producing stress hormones within cells.
研究人员在关注一种新的化合物11beta -HSD1,它能阻碍一种酶,可以帮助细胞产生应激激素。
The researchers are looking at a new chemical compound which blocks an enzyme, known as 11beta-hsd1, which helps produce stress hormones within cells.
耶鲁研究小组发现JNK应激信号从一个细胞向另一个细胞传导,但这个传导途径能被阻断。
The Yale team found that the JNK stress signaling travels from one cell to the next, but that the propagation can be blocked.
同样,在卵巢癌小鼠模型中,抑制应激和相关的去甲肾上腺素和肾上腺素增加可防止肿瘤细胞发生失巢凋亡,从而促进肿瘤生长。
Similarly, in a mouse model of ovarian cancer, restraint stress and the associated increases in norepinephrine and epinephrine protected the tumor cells from anoikis and promoted their growth.
差异表达的基因的功能涉及细胞生长增殖调控、凋亡、细胞周期、应激反应、转运及代谢酶等方面。
The expressions of the various genes modulated cell growth and proliferation, apoptosis, cell cycle, stress response, transporters, chaperones, transcription regulation and drug metabolism.
这项工作显示了氧化低密度脂蛋白在骨桥蛋白基因表达中的作用,并且进一步解释了氧化应激在细胞因子调节中的作用。
This work demonstrates the role of OxLDL in the expression of the OPN gene and further highlights the role of oxidative stress in the regulation of this cytokine.
目的研究三氯乙烯对大鼠肝细胞DNA损伤和肝组织氧化应激的作用。
To study the effects of trichloroethylene on DNA damage in rat hepatocytes and oxidative stress in rat liver tissue.
自由基可引起氧化应激,长期下来可引起炎症以及细胞内一些不健康的改变。
Free radicals contribute to oxidative stress, which, over time, can cause inflammation and other unhealthy changes in your cells.
泛素缀合途径参与细胞的多种代谢过程,包括DNA损伤修复、细胞周期调控及应激反应等。
The ubiquitin-conjugating pathway involves in numerous metabolic processes in cells, including DNA damage repair, cell cycle control, stress responses and so on.
在这项研究中,人类卵巢癌细胞系暴露到应激激素去甲肾上腺素或肾上腺素任何一种都能保护它们免疫失巢凋亡。
In the study, exposure of human ovarian cancer cells lines to either of the stress hormones norepinephrine or epinephrine protected them from anoikis.
人们认为,线粒体dna的破坏通常与氧化应激行管,并且导致细胞死亡。
It is thought that the common link is oxidative stress which damages the mitochondrial DNA leading to cell death.
氧化应激是由于细胞损伤引起的自由基增多,而机体的清除能力却不足所导致的。
Oxidative stress is an imbalance between the production of cell-damaging free radicals and the body's ability to neutralize them.
方法在热应激条件下,用PCR法从结肠腺癌细胞获取HSP70基因。
Methods Under a condition of heat stress, amplify HSP70 gene from colon cancer cells by PCR.
能改善寒冷应激所致红细胞免疫、白细胞吞噬以及淋巴细胞转化等功能低下。
It also could evidently improve the immunologic hypofunction (WBC phagocytosis and lymphocyte transformation etc.) induced by the cold stress in mice.
因此TGP可以保护高糖诱导的肾小球系膜细胞氧化应激损伤。
Therefore we conclude that TGP could protect mesangial cells against oxidative stress induced by high glucose.
原因可能是细胞膜的应激部被包裹微细胞的抗体遮盖了。
The reason may be that the provocative parts of the membrane are masked by antibodies with which the minicells are coated, Dr.
方法体外培养的A549细胞分为高温应激组和BPDE组。
Methods A549 cells cultured in vitro were divided into heat stress group and BPDE group.
海马细胞的应激也可以阻断记忆形成,此外还有一些药物摄入后也可能产生失忆作用。
Stress on the hippocampal cells also can block memory formation. So can consumption of other drugs.
海马细胞的应激也可以阻断记忆形成,此外还有一些药物摄入后也可能产生失忆作用。
Stress on the hippocampal cells also can block memory formation. So can consumption of other drugs.
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