近年来的研究发现,许多癌基因和抑癌基因相关产物为细胞生长、增殖、分化等信号转导途径的成员。
It is known that many related products of oncogenes and anti - oncogenes take part in the signal transduction of grow, proliferation and differentiation of cells.
研究了环六亚甲基双乙酰胺对人成骨肉瘤MG-63细胞的增殖和相关基因表达的影响。
In this paper, we studied the effects of HMBA on the proliferation and expression of genes in human osteosarcoma MG-63 cells.
结论PASG基因作为上游调控基因,通过改变基因组甲基化水平调控下游一系列细胞增殖分化相关基因表达。
Conclusions AS an upstream regulator, PASG can regulate expression of a series of cell proliferation, differentiation relevant downstream genes through changing methylation levels of genomic DNA.
这些基因分别与细胞增殖、基因转录、凋亡、信号转导、DNA损伤修复、肿瘤分化和浸润转移及细胞周期调节等相关。
These genes were involved in cell proliferation, gene transcription, apoptosis, signal transduction, DNA damage and repair, tumor differentiation and metastasis, cell cycle, and so on.
用免疫组化方法检测胃黏膜细胞的凋亡和增殖以及凋亡相关基因BCL-2、BAX的表达。
We used immunohistochemistry to detect the gastric mucosal cells apoptosis, proliferation and the expression of BCL-2, BAX.
结论四个基因片段为与细胞的增殖与分化相关的已知基因,有一个基因片段可能为新的功能性的白血病基因。
Conclusion the four gene fragments were amplified from known genes involved in cell proliferation and differentiation, while the one unknown gene fragment maybe from a new functional leukemia gene.
目的既往研究表明LRP16基因是一个雌激素反应基因,其表达水平与乳腺癌细胞增殖及侵袭密切相关。
Objective Previous studies have demonstrated that LRP16 is an estrogen-responsive gene, its expression level is closely related with proliferation and invasive growth of human breast cancer cells.
结论FHIT基因可能参与肿瘤细胞增殖的调控,FHIT基因表达下降可能与肺癌的发生密切相关。
Conclusion FHIT gene may play a role in the regulation of cell proliferation of lung cancer, and the reduction in FHIT expression may be related to the pathogenesis of lung cancer.
目的:研究肿瘤相关抗原编码基因CHP2对细胞增殖作用的影响。
Objective: To study the effect of cell proliferation transfected with tumor associated antigen encoding gene CHP2.
目的:探讨壶腹癌中抑癌基因P16蛋白与增殖细胞核抗原(PCNA)表达的相关性及其与肿瘤临床病理特征的关系。
Objective:To study the expression of P16 protein and PCNA in ampullary carcinoma and its relation with its pathological features.
③LRP16基因的表达量与垂体泌乳素腺瘤细胞增殖活性存在相关关系,LRP16基因可能参与垂体泌乳素腺瘤细胞增殖的调控。
The expression of LRP16 is correlated with cell Proliferation of Prolactinomas and LRP16 may contributet to the regulation of cell Proliferating.
③LRP16基因的表达量与垂体泌乳素腺瘤细胞增殖活性存在相关关系,LRP16基因可能参与垂体泌乳素腺瘤细胞增殖的调控。
The expression of LRP16 is correlated with cell Proliferation of Prolactinomas and LRP16 may contributet to the regulation of cell Proliferating.
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