对体外培养的肿瘤细胞增殖抑制率可高达60.10%,与对照组比较差异有显著性(P<0.05);
The inhibitory rate of JMME on tumor cell cultivated in vitro(60.10%)was higher than that in control group(P<0.05).
方法以MTT法测定细胞增殖的抑制率。
Methods: MTT methods was used to determine the inhibiting rate of cell proliferation.
方法采用台盼蓝拒染法,在不同条件下测定细胞增殖的抑制率。
Methods The inhibitory rates of cell growth were tested by trypan blue stain assay in the different conditions.
分别采用台盘蓝拒染法及流式细胞术,在不同条件下测定细胞增殖的抑制率及细胞周期的分布。
Methods The cell growth was tested by trypan blue stain assay and the cell cycle was analysed by flow cytometry in the various conditions.
结论BCNU PLGA缓释微球可以抑制C6胶质瘤细胞的增殖,随释放时间延长细胞生长抑制率逐渐上升。
Conclusion BCNU loaded PLGA wafer can inhibit the proliferation of C6 glioma cell and demonstrate gradually increased tendency with prolonged release time.
结论BCNU PLGA缓释微球可以抑制C6胶质瘤细胞的增殖,随释放时间延长细胞生长抑制率逐渐上升。
Conclusion BCNU loaded PLGA wafer can inhibit the proliferation of C6 glioma cell and demonstrate gradually increased tendency with prolonged release time.
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