目的：总结成肌细胞在骨骼肌收缩功能和细胞基因治疗研究中的应用。
OBJECTIVE: To summarize the application of myoblast in skeletal muscle contraction and gene treatment research.
目的：提供一个对目前状况和胎儿干细胞基因治疗中的作用委员会的意见。
Objective: To provide a Committee opinion on the present status and role of stem cells in fetal genetic therapy.
从而证明该方法所获取的大量皮肤成纤维细胞可作为一种安全、可靠的靶细胞用于自体皮肤成纤维细胞基因治疗研究。
All these show that fibroblast cells harvested and cultured in this method could be safe and stable targeted cells used for the study of gene therapy of autologous skin fibroblast.
对非人类的灵长类动物的研究为aids活体病毒感染模型的干细胞基因治疗法在实验上提供解决基本问题的可能性办法。
Studies in nonhuman primates offer the opportunity to experimentally address basic questions regarding stem cell gene therapy for AIDS in an in vivo disease model.
对于后天性的疾病，比如癌症，基因治疗试验是通过引入可以杀死癌细胞的基因。
For acquired diseases, such as cancer, gene-therapy trials are introducing genes that are intended to kill cancerous cells.
稍作改动，药品也许对治疗数百种疾病有效，以此兑现诸如实现干细胞和基因治疗这些神奇疗法的承诺。
With a slight redesign, the drug might work for hundreds of diseases, fulfilling the promise that wonder cures like stem cells and gene therapy have failed to deliver.
结果，AMD成为多项高科技的焦点，包括RNA干扰，基因治疗和干细胞。
As a result AMD has been the focus of several high-tech approaches, ranging from RNA interference to gene therapy and stem cells.
同时，在慢性粒细胞白血病治疗方面，另两个采用类似基因治疗的研究也收获成果。
Two other studies, meanwhile, confirmed that a similar approach to chronic myelogenous leukaemia continues to bear fruit.
据最新一期的科普杂志《细胞》介绍，奥地利科学家发现，基因治疗可以抑制身体无用脂肪的形成。
Austrian scientists found that gene therapy is able to inhibit the formation of body's useless fat. according to the latest issue of the scientific magazine Cell.
人们希望，改构后的腺病毒在基因治疗方面能起到重要的作用，例如，作为载体基因携带治疗性基因到达细胞内。
The hope is that modified adenovirus could play a role in gene therapy, used as a vector (carrier) for delivering therapeutic genes to the interior of cells.
VHL基因可作为临床诊断指标，并可望成为肾透明细胞癌基因治疗的重要目的基因。
The VHL gene may be useful as a marker gene for the diagnosis of RCC and as a target gene for molecular therapy.
在此，我们研究了用白介素(IL) - 13进行腺病毒载体基因治疗的效果，白介素(IL) - 13是一种在急性肾移植损伤中有强大免疫调节特性的细胞因子。
Here we investigate the effects of adenovirus-mediated gene therapy with interleukin (IL) -13, which is a cytokine with strong immunomodulatory properties, on acute renal allograft injury.
随着在细胞分子水平上对疾病发病机制认识的深入，基因治疗已成为目前医学分子生物学最重要的研究领域之一。
With deeper cognition about mechanisms of disease at the cellular and molecular level, gene therapy has become one of the most important research fields in medical molecular biology at present.
结论：成肌细胞可以为骨骼肌在收缩功能上的研究提供一个很好的研究平台，其在基因治疗研究中的应用也为肌组织工程的研究奠定了基础。
CONCLUSION: Myoblast provides a research platform for skeletal muscle contraction function, which also lays a foundation for the muscle tissue engineering research in gene treatment.
纳入标准：有关成肌细胞的生物学特性、在骨骼肌收缩中的应用、在基因治疗中应用方面的文献。
Inclusive criteria: Literature about the biological characteristics of myoblast, the application in skeletal muscle contraction and gene treatment.
虽然基因治疗的整体取得了很大的进展，但人们仍然需要开发更好的和更安全的将基因注入细胞的注射方式。
Despite the overall progress, there is still a need to develop improved and safer approaches to deliver genes into cells.
肿瘤靶向基因治疗的主要目的是用靶向性的载体将治疗基因靶向传递到肿瘤细胞。
A major goal of tumor-targeting gene therapy is to transfer genes efficiently to tumor cells by targeted vectors.
目的：探讨慢病毒载体在白血病细胞中的基因转导效率，为白血病基因治疗提供关键依据。
Objective to investigate the gene transduction efficiency of lentiviral vector in leukemia cells to provide key basis for leukemia gene therapy.
基因治疗的目的是将遗传物质导入细胞并使之得到适宜水平的表达，以纠正机体的遗传缺陷，恢复细胞的正常功能或杀死癌细胞及致病微生物。
The ultimate goal of gene therapy is correction of the genetic disorders by introducing the genetic materials into targeted cells, and gene expression should be permanent and at an appropriate level.
造血干细胞的应用包括造血干细胞移植和作为基因治疗的靶细胞。
Application of hemopoietic stem cells included hemopoietic stem cell transplantation and as target cells for gene therapy.
摘要腺病毒载体具有高效转染和低细胞毒性的特点，已成为基因治疗研究中应用最广泛的载体之一。
Adenovirus vectors have the characteristics of high transfection efficiency and low cytotoxicity, and they have become most widely used vectors for gene therapy.
重点介绍了各种胸苷激酶(tk)同工酶的差异及其与癌症和细胞周期的关系，并介绍了最近利用tk基因进行肿瘤基因治疗研究的进展。
This paper introduce the differences in thymidine kinase (tk) isoenzymes and the relation of them to cancer and cell cycle as well as the progress of gene-therapy of cancer based on tk gene.
文章从细胞信号传导通路、细胞生存途径、基因治疗及血管生成四方面简要介绍这些新靶点和已经或正在研发的新药物。
This review briefly focused on the new targets and agents from the following four aspects: signal transduction pathway, cell survival pathway, gene therapy, and angiogenesis.
基因治疗是指改变细胞遗传物质为基础的医学治疗。
Gene therapy is a medical intervention based on modification of genetic materials in living cells.
纳米微粒在癌症的监测、治疗，细胞和蛋白质的分离，基因治疗，靶向和缓释控药物等中都有着广泛的应用。
Nanobiomaterials can be widely used in the fields of monitoring and therapy of cancer, separation of cells or proteins, genic therapy, drug target delivery and release, and so forth.
逆转录病毒是最常用的基因治疗载体，但对人类细胞的基因导入率较低。
Retrovirus (RV) is the most widely used vector for gene transfer, but its efficiency is very low for human cells.
基因治疗是将DNA转染进入目的细胞，修复遗传错误或产生治疗因子。反义寡核苷酸的应用是基因治疗的主要手段之一。
The aim of gene therapy is to transfect DNA into target cells, in which utilizing antisense oligonucleotides is a main method.
基因治疗是将DNA转染进入目的细胞，修复遗传错误或产生治疗因子。反义寡核苷酸的应用是基因治疗的主要手段之一。
The aim of gene therapy is to transfect DNA into target cells, in which utilizing antisense oligonucleotides is a main method.
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