为了克服这一方法的弱点,提出分块pca,并以此为基础形成一种提取细胞周期调控基因的新方法。
A novel extraction approach based on partitioning PCA for extracting cell cycle-regulation genes was established.
肿瘤是一种基因疾病,在当前分子生物学领域中,细胞癌变与细胞信号传导系统、细胞周期调控、细胞的生长和分化,以及细胞凋亡等均有关联。
Tumor is a kind of gene disease in the field of molecular biology, canceration is correlated with signal transduction system, regulate of cell cycle, differentiation and development of cell apoptosis.
差异表达的基因的功能涉及细胞生长增殖调控、凋亡、细胞周期、应激反应、转运及代谢酶等方面。
The expressions of the various genes modulated cell growth and proliferation, apoptosis, cell cycle, stress response, transporters, chaperones, transcription regulation and drug metabolism.
目的:p 53基因参与细胞周期调控。
目的:研究艾灸对HCC癌前病变大鼠细胞周期调控相关基因的影响。
Objective: To study the effect of moxibustion in relative cell cycle control gene change of HCC precancerous lesion on big rats.
热休克蛋白可能有助于细胞周期调控通过与原癌基因的产品或抑癌基因的产品。
Heat Shock Proteins may contribute to cell cycle regulation by interacting with proto-oncogene products or tumor suppressor gene products.
这些基因涉及细胞周期、免疫调控、脂肪代谢、泡沫细胞形成、信号转导等过程。
These genes were related to cell cycle, immune modulation, lipid metabolism, foam cell formation, and signal transduction.
这些受影响的基因主要基因涉及转录、RNA加工细胞周期调控等过程。
Genes involved in transcription, RNA processing, and cell cycle regulation were particularly affected.
在调控基因中,大多是众多的生长因子基因和影响细胞粘附、细胞信号转导及细胞周期调控或者其它功能的基因。
Among the regulated genes are numerous growth-factor genes and genes affecting cell adhesion, cell signaling, cell-cycle regulation, and other functions.
组蛋白脱乙酰基酶与组蛋白脱乙酰基酶抑制剂通过对组蛋白乙酰化水平的调控,影响特定基因的表达,改变细胞周期的进程。
HDAC and histone deacetylase inhibitors (HDI) can affect expression of some specific genes and induce cell differentiation growth arrest and apoptosis through regulating histone acetylation level.
真核生物对维持基因组的稳定性及防止非整倍体的产生,有其一套完整的保护机制,即细胞周期调控、检验点调控以及对损伤DNA的修复。
To ensure genome integrity and prevent aneuploidy, eukaryotes have evolved an integrated protective mechanism, including cell cycle control, checkpoint control, and DNA repair.
对该基因的克隆和表达分析为今后研究家蚕胚胎发育及细胞周期调控奠定了基础。
The cloning and expression analysis of BmCcnl1 provide the basis for the research of the embryonic development and cell cycle regulation.
泛素- 蛋白酶体通路介导细胞蛋白质的降解,在细胞周期、基因转录及表达、 抗原提呈和炎症演进等方面发挥调控作用。
Ubiquitin-proteasome pathway mediates the degradation of cell protein and modulates cell cycle, gene translation and expression, antigen presentation and inflammation development.
本项基因治疗策略以直接调控细胞周期的抑癌基因为靶向治疗基因,为肺癌基因治疗提供了可靠的理论依据。
The strategy targeted to the tumor suppressor gene that regulates the cell cycle directly, obtained satisfactory results, and provided a reliable theory for lung cancer gene therapy.
差异性表达主要涉及细胞凋亡、细胞增殖、细胞周期调控和信号转导的基因。
Among these genes, a high proportion of genes were associated with apoptotic, cell cycle, cell proliferation and cell signal transduction.
CDK9基因的过表达未引起细胞周期发生显著变化,其可能并不参与细胞周期的调控。
Its overexpression did not cause significant changes in cell cycle, which seemed that no detectable relationship existed between CDK9 and cell cycle regulation.
CDK9基因的过表达未引起细胞周期发生显著变化,其可能并不参与细胞周期的调控。
Its overexpression did not cause significant changes in cell cycle, which seemed that no detectable relationship existed between CDK9 and cell cycle regulation.
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