方法:应用SP免疫组化法,检测P 21, P27等细胞周期依赖性激酶抑制剂和增殖细胞核抗原(pcna)在角膜上皮不同部位的表达情况。
METHODS: the expressions of CKI, P27, P21 and proliferating cell nuclear antigen (PCNA) were tested in different regions of corneal epithelium by SP immunohistochemistry.
目的探讨翼状胬肉组织中细胞周期蛋白依赖性激酶抑制剂P16的表达,了解其在翼状胬肉发病机制中的作用。
Objective To observe the expression of cyclin kinase inhibitor P16 in pterygium and to investigate its effects on the pathogenesis of pterygium.
目的观察细胞周期蛋白依赖性激酶- 2 (CDK - 2)在SH -SY5Y细胞中的表达情况。
Objective To investigate the expression of cyclin-dependent kinase-2 (CDK-2) gene in SH-SY5Y cells.
结论翼状胬肉中细胞周期蛋白依赖性激酶抑制剂p16的低表达可能导致翼状胬肉细胞周期紊乱,其增殖失去控制。
Conclusion The lower expression of cell circle related kinase inhibitor in pterygium may play an important role on proliferation and pathogenesis of pterygium.
在植物中a型和B型细胞周期蛋白依赖性激酶直接参与调控细胞周期。
In plants, a - and B-type CDKs are directly involved in cell cycle regulation.
主要观察指标:神经细丝的磷酸化程度及糖原合酶激酶3、细胞周期依赖性蛋白激酶5的酶活性。
MAIN OUTCOME MEASURES: The degree of NF phosphorylation and the activities of GSK-3 and CDK-5 were mainly observed.
主要观察指标:神经细丝的磷酸化程度及糖原合酶激酶3、细胞周期依赖性蛋白激酶5的酶活性。
MAIN OUTCOME MEASURES: The degree of NF phosphorylation and the activities of GSK-3 and CDK-5 were mainly observed.
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