成骨细胞分化所需的第二个重要转录因子是一种具有锌指结构的,对骨形成十分重要的转录因子。
A second important transcription factor required for osteoblastic differentiation is osterix.
问题关键在于找到正确的诱导干细胞分化成心脏细胞,神经细胞,制造胰岛素的细胞或者其他细胞的生长因子的正确方法。
The key lay in finding just the right recipe of growth factors and nutrients to induce a stem cell to become a heart cell, a neuron, an insulin-making cell or something else.
这就引出问题,转录因子是否能直接诱导其它明确的体细胞,而不仅是未分化状态的细胞。
This raised the question of whether transcription factors could directly induce other defined somatic cell fates, and not only an undifferentiated state.
目的观察肝细胞生长因子对神经干细胞向神经元细胞方向分化的作用。
Objective to explore the effect of hepatic growth factor on the neuronal differentiation of the neural stem cells.
胰岛素样生长因子系统在调节细胞增殖、分化与抑制凋亡中发挥重要作用。
Insulin-like growth factor (IGF) system plays an important role in regulating cell proliferation and differentiation, and inhibiting apoptosis.
目的:了解多潜能造血祖细胞向红系分化过程中造血因子受体的改变。
Objective: to understand the changes in hematopoietic growth factor receptors during erythroid differentiation of pluripotent cells.
研究表明,组蛋白的乙酰化与去乙酰化状态,可作用于T、B细胞的发育、分化、成熟、分泌及表面因子的表达等多个方面。
Studies had shown that acetylation and deacetylation of histone are of certain value on t, B cell's development, differentiation, maturation, secretion and surface factor's expression etc.
肽类生长因子影响着多种细胞生理过程,包括细胞增殖、分化、移行和存活。
The peptide growth factors influence diverse cellular processes, including cell proliferation, differentiation, migration and survival.
EYA蛋白作为重要的转录调控因子,直接参与胚胎发育过程中的细胞增殖、组织分化和器官发育。
EYA was thought to function as a transcriptional regulatory factor that plays an important role in cell proliferation, tissue differentiation and embryonic development.
细小病毒的复制紧紧依赖于和增殖及分化有关的细胞因子,尤其是和细胞周期S-期有关的因子。
The replication of parvovirus is strongly dependent on cellular factors associated with proliferation and differentiation, especially those related to the S-phase of the cell cycle.
促进T细胞产生淋巴因子,增强诱杀性细胞NK的分化。
The promotion of T cells to produce lymphokines , and enhance cell Traps NK differentiation.
在此论文中阐述了这些因子对破骨细胞的分化和功能具有重要作用。
Here we show that these three factors have critical roles in osteoclast differentiation and function.
哺乳动物促性腺激素细胞的增殖分化受多种因子影响,它分泌的促性腺激素在生殖调控中占有中心地位。
The differentiation of mammalian gonadotroph was influenced with many factors, and the gonadotrophin takes an important part in reproduction control.
MSC能产生许多促进造血细胞归巢或增殖和分化的细胞因子,因此在促进造血恢复中发挥重要的作用。
MSC can produce a variety of cytokines that promote the homing or proliferation and differentiation of hematopoietic cells, and accordingly play important roles in promoting hematopoietic recovery.
目的观察视黄酸对人横纹肌肉瘤细胞的诱导分化作用及对生肌调节因子(MRF)表达的影响。
Objective To study the effects of retinoic acid on the differentiation of human rhabdomyosarcoma cells and on the expression of myogenic regulatory factor (MRF).
目的:探讨肝细胞生长因子(HGF)诱导小鼠胚胎干细胞(ESC)体外定向分化为肝细胞的细胞功能表现。
Objective To investigate the role of murine Hepatocyte growth factor(HGF) inducing mouse embryonic stem cells(ESC) in vitro to commitmently differentiate into hepatocyte.
实验通过原位分子杂交技术,检测人骨髓巨核细胞分化发育过程中神经生长因子( NGF)基因表达情况。
The expression of nerve growth factor (NGF) gene during development of megalocaryocytes was studied by in situ hybridization.
激素和脂肪细胞因子可以调控脂肪组织的生长、分化及机体脂肪沉积。
Growth and differentiation processes of adipose tissues could be regulated by hormones and adipocytokins.
另外研究血管内皮生长因子(VEGF)和传代培养对细胞分化、扩增动力学和细胞凋亡的影响。
In addition, we tested the effect of vessel endothelial growth factor (VEGF) and passage on cell differentiation, expansion kinetics and apoptosis.
方法:用液体或半固体培养法及流式细胞术测定血小板因子4对CD34阳性脐血细胞的增殖与分化的作用。
Methods: Liquid and semi solid culture systems as well as flow cytometry were used to study the effect of PF4 on the proliferation and differentiation of CD34+ cord blood cells.
结论:FN能促进牙槽骨细胞的增殖及蛋白合成,但促进细胞分化的能力有限,尚需其他生长因子的协助以促进组织再生。
Conclusion: FN enhances the proliferation of ABCs, but has limited effects on cell differentiation. Therefore other growth factors are needed to act in concert to promote tissue regeneration.
BMP是骨生长的启动因子,能诱导骨髓基质细胞分化为成骨细胞和骨细胞,促进钙化作用,产生钙化的骨基质。
BMP is the start of bone growth factor, can induce bone marrow stromal cells differentiate into bone cells and bone cells, to promote calcification, resulting in calcification of bone matrix.
肝细胞转录因子3蛋白(HNF3)在调节新陈代谢及肝脏、胰脏等代谢组织的分化过程中起着关键作用。
Hepatocyte nuclear factor 3 (HNF3) proteins play pivotal roles in the regulation of metabolism and the differentiation of the metabolic tissues such as pancreas and liver.
细胞因子信号转导抑制蛋白(SOCS)通过与受体介导的信号转导,调节细胞增殖、生长、分化及炎症发生等。
Suppressors of cytokine signaling (SOCS) associates with receptor-mediated signal transduction pathway, which can regulate cell proliferation, growth, differentiation and inflammation et al.
目的通过促分化因子的调节作用对神经干细胞向胆碱能神经元的定向分化进行探讨研究。
To study nerve stem cell directional differentiation to cholinergic neuron by adjusting action of promote differentiation factors.
目的:观察胶质源性神经营养因子在神经前体细胞的存活和分化过程中的作用及其协同因子。
AIM to observe the effects of glial-derived neurotrophic factors on survival and differentiation of neural precursor cells and its cooperative factors.
近年研究表明,胚胎干细胞在细胞因子、激素、微环境等作用下能够分化为软骨细胞。
Recent study shows that, embryonic stem cells can differentiate into cartilage cells in the effect of cytokines, hormones, micro? Environment etc.
目的:研究关节软骨细胞的原代分离及体外培养,了解表皮细胞生长因子(EGF)对其生长和去分化趋势的影响。
Objective: To study the isolation and culture of chondrocyte of joint cartilage, and the influence of EGF on its growth and dedifferentiation.
为维持细胞在培养过程中的未分化状态,需要采用饲养层细胞培养,同时设计合理的培养液配方并添加多种抑制分化或促进增殖的细胞因子。
Feeder layer cells and suitable culture medium that supplemented with cytokines of promoting proliferation or restraining differentiation were crucial to keep chicken es in an undifferentiated state.
分化培养中加入碱性成纤维细胞生长因子能够提高胆碱能神经元分化的比例。
The addition of basic fibroblast growth factor in differentiation culture could increase the proportion of cholinergic neurons.
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