目的:观察钙离子通道阻滞剂盐酸维拉帕米对3T3鄄L1前体脂肪细胞分化及脂质积聚的影响。
Objective:To observe the effect of verapamil on the differentiation and the lipid accumulation of 3T3-L1 preadipocyte.
目的:临床试验中对组蛋白脱乙酰基酶阻滞剂(HDACi)的研究目的在于诱导细胞分化,生长停止,和肿瘤细胞的凋亡。
Purpose: Histone deacetylase inhibitors (HDACi) are being studied in clinical trials with the aim to induce cellular differentiation, growth arrest, and apoptosis of tumor cells.
目的:了解干细胞动员剂动员的骨髓干细胞的心肌细胞分化潜能及对缺血心肌的影响。
Objective: to investigate the potential of differentiating into myocytes of the granulocyte colony stimulating factor (g CSF) and Simvastatin mobilized bone marrow stem cells.
结果表明川芎嗪能定向诱导小鼠骨髓间充质干细胞分化为神经元样细胞,是较理想的诱导剂。
These results suggested that the mouse bone marrow-derived mesenchymal stem cells could be differentiated into neuron-like cells in vitro with the induction of tetramethylpyrazine.
结论:APS有可能成为既能促进正常造血,又能抑制白血病等肿瘤细胞增殖,并诱导其凋亡或分化的天然诱导剂。
Conclusion: APS may not only promote normal hematopoiesis, but also inhibit the proliferation of leukemia cell and it can be a natural inducer for therapy of malignant tumor.
神经节苷脂gm3作为一种促分化剂已在多个细胞瘤株模型中得到证实,但迄今为止其促分化的详细机制仍未阐明。
Ganglioside GM3 has been proved to be a physiological cell differentiation inducer in several human leukemia cell lines. However, the inducing differentiation mechanism of GM3 remains unclear.
结论:釉基质蛋白可作为一种成骨诱导剂,能有效增强大鼠脂肪源性干细胞体外增殖活性并诱导其成骨分化。
Conclusion: Enamel matrix proteins may be used as an osteoinductive agent, due its enhancing effect on adipose-derived stem cells proliferation and osteogenic differentiation.
目的:研究肿瘤细胞分化诱导剂尿多酸肽(CDA - II)对人胃癌细胞的体外抑制作用。
Objective: to study the inhibitory effect of Uroacitide (CDA-II) on human gastric cancer cell in vitro.
目的探讨白三烯(LT)B4能否不依赖细胞核因子资B受体激活剂配体(RANKL)直接促进人破骨细胞的分化和激活。
Objective To determine whether leukotriene B4 (LTB4) could directly stimulate human osteoclast differentiation and activation independent of RANKL (ODF).
本研究旨在探讨诱导分化剂与细胞毒化疗药抗胶质瘤的联合效应。
This study was designed to investigate anti tumor effects of differentiation inducing agent in combination with cytotoxic chemotherapeutic drug against glioma.
诱导分化是指在分化诱导剂的存在下,恶性肿瘤细胞的形态、生物学或生物化学方面的诸多标志均向正常细胞的方向分化,甚至完全转变成正常细胞。
By derived differentiation, we mean that under the effect of differentiation inducer, malignant tumor cell has the tendency to differentiate to normal cell, even became normal cells.
结论:本法无需添加化学诱导剂,为一种简便、经济的诱导体外培养小鼠es细胞分化为心肌细胞的方法。
CONCLUSION: a simple and economical method was established to induce mouse es cells cultured in vitro to differentiate into cardiomyocytes without using any chemical reagents.
中药在诱导干细胞分化为心肌细胞方面的研究较新,随着研究深入,将会有越来越多的中药诱导剂被发现。
It is new for traditional Chinese medicine to induce stem cell differentiation into cardiomyocytes. With deep research, more and more traditional Chinese medicine inducer will be found.
中药在诱导干细胞分化为心肌细胞方面的研究较新,随着研究深入,将会有越来越多的中药诱导剂被发现。
It is new for traditional Chinese medicine to induce stem cell differentiation into cardiomyocytes. With deep research, more and more traditional Chinese medicine inducer will be found.
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