近年来对凋亡发生和调控机制的研究表明,细胞凋亡途径主要有两条:线粒体途径和死亡受体途径。
In recent years, studies of occurrence and regulation mechanism of apoptosis show that the two major apoptotic pathways are the mitochondrial and death receptor pathways.
结论:苦参碱能诱导C6胶质瘤细胞的凋亡,其机制与死亡受体途径和线粒体途径的众多基因有关。
Conclusion: Matrine can induce C6 glioma cell apoptosis and the mechanism might be related to a number of genes involved in death receptor pathway and mitochondrial pathway.
死亡受体通过细胞内信号传导途径可诱导细胞凋亡,与机体的生长、发育、病变和死亡有关。
Death receptors induce apoptosis by intracellular signaling transmission and relate to body growth, development, disease and death.
死亡受体在胰腺癌中高表达,可能在TRAIL诱导胰腺癌细胞凋亡的机制中发挥重要的作用。
High death receptor expression may play an important role in TRAIL inducing pancreatic carcinoma apoptosis.
我们的结果还进一步表明PD-1/PD-L1途径对T淋巴细胞凋亡的影响是同时通过内源性死亡受体途径和外源性死亡受体途径产生的。
Our results further showed that the PD-1/PD-L1 pathway which could reduce the rate of T lymphocyte apoptosis via the death receptor pathway of endogenous and exogenous death receptor pathway.
我们的结果还进一步表明PD-1/PD-L1途径对T淋巴细胞凋亡的影响是同时通过内源性死亡受体途径和外源性死亡受体途径产生的。
Our results further showed that the PD-1/PD-L1 pathway which could reduce the rate of T lymphocyte apoptosis via the death receptor pathway of endogenous and exogenous death receptor pathway.
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