新的研究发现了一种通过操纵宿主细胞内的一种常见信号通路来破坏早期宿主免疫反应并提高致病性的以前未知的酶反应机制。
New research identifies a previously unknown enzymatic mechanism that subverts the early host immune response and promotes pathogenicity by manipulating a common signaling pathway in host cells.
这项研究说明了EGFR–SGLT1通路通过维持细胞内的葡萄糖水平，阻止自噬性细胞死亡，从而为肿瘤细胞提供了生存优势。
This study reveals that EGFR–SGLT1 may confer a survival advantage to cancer cells by maintaining a basal level of intracellular glucose and preventing autophagy.
已经提出了几个假说来连接物理力和细胞内信号转导通路但是许多情况中机械转导的机制还不清楚。
Several hypotheses have been advanced that link physical forces to intracellular signalling pathways, but in many cases the molecular mechanisms of mechanotransduction remain elusive.
它既可以作为整合各种信号转导通路的上游信号如胰岛素、生长因子和有丝分裂原的整合器，又可以作为感知细胞内营养与能量水平及还原状态的感受器。
It combines input from multiple upstream pathways, including insulin, growth factors and mitogens while functioning as a sensor of cellular nutrient and energy levels and redox status.
他说如果细胞内钙钠离子储留，意味着你的神经元要和你说再见了，某些循环通路可能走向不可逆转的死亡。
"You then get a simultaneous build-up of calcium and sodium in the cell, and it's 'Goodbye to your neuron. ' It goes at some point into an irreversible cycle of death, " he said.
这种细胞间及细胞内的信号通路非常复杂，整个信号通路在多个不同水平被调节。
Signaling between and within cells is a highly complex process that is regulated on several different levels in the signal pathways.
本文综述了CARP基因与蛋白质结构、CARP的表达模式及其表达调控、参与调节CARP的细胞内信号转导通路、CARP在肌肉发育中的作用，以及MARP家族其他成员。
This paper reviews the structure of CARP and its functional role during striated muscle development. The signal pathway involved in CARP expression, and the other members of MARP family.
用分子细胞生物学、生物化学、遗传学等手段研究肿瘤细胞内的信号传导通路与肿瘤发生机理；筛选肿瘤治疗特异性靶标与新药开发。
Using molecular cell biology, biochemistry, genetics and other approaches to study the signal transduction pathways in cancers and establish tumor targeting strategy for drug development.
GSK3底物众多，其功能与细胞的存活与凋亡，结构与能动性以及细胞内众多信号传导通路密切相关。
GSK3 regulates many functions including cell survival and apoptosis, structure and motility, intracellular signaling pathways and so on.
GSK3底物众多，其功能与细胞的存活与凋亡，结构与能动性以及细胞内众多信号传导通路密切相关。
GSK3 regulates many functions including cell survival and apoptosis, structure and motility, intracellular signaling pathways and so on.
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