可见，肿瘤细胞上共刺激分子缺陷是肿瘤免疫逃逸的重要机制之一。
Therefore, deficiency of costimulatory molecules on tumor cells is one of the important mechanisms of tumor immune escape.
近年来，肿瘤坏死因子受体超家族成员-OX40 (CD134)，作为一共刺激分子对于维持CD 4 +T细胞的活化、增值、存活起到关键性作用。
In recent years, tumor necrosis factor receptor (TNFR) family member-OX40 (CD134), as a key co-stimulatory molecule, involved in maintenance of activation, proliferation, survival of CD4 + t cells.
目的：研究银屑病患者外周血T淋巴细胞表面共刺激分子CD80的表达及其与银屑病皮损面积和严重程度指数（PASI）的相关性。
Objective: To measure the expression of co-stimulatory molecule CD80 on peripheral blood T lymphocytes in patients with psoriasis and its correlation with psoriasis area and severity index (PASI).
而CD 80是能够与CD 28分子结合的共刺激分子之一，它与T细胞表面CD 28分子的结合为T细胞有效活化提供第二信号。
CD80 is one of the co-stimulatory molecules binding CD28, which binds CD28 on the surface of t cells to provide second signal for efficient activation of t cells.
目的探讨可诱导共刺激分子(ICOS)在系统性红斑狼疮(SLE)患者外周血t淋巴细胞的表达。
Objective to investigate the expression of inducible co-stimulator (ICOS) on t lymphocytes in peripheral blood from the patients with systemic lupus erythematosus (SLE).
单用DNA疫苗或联用TLR免疫的组间的树突状细胞表面上的共刺激分子的表达水平没有统计学上的显著差异。
No statistically significant difference in the expression levels of co-stimulatory molecules on dendritic cells surface between the groups immunized with DNA vaccine alone or with TLRs.
单用DNA疫苗或联用TLR免疫的组间的树突状细胞表面上的共刺激分子的表达水平没有统计学上的显著差异。
No statistically significant difference in the expression levels of co-stimulatory molecules on dendritic cells surface between the groups immunized with DNA vaccine alone or with TLRs.
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