本文就基质金属蛋白酶及其组织抑制剂的性质、结构以及功能进行了综述。
In this paper, the property, structure, and function of MMP and TIMP were reviewed.
脑缺血;黄体酮;基质金属蛋白酶9;金属蛋白酶组织抑制剂1;血脑屏障。
Cerebral ischemia; Blood brain barrier; Progesterone; Matrix metalloproteinase9; Tissue inhibitor of metalloproteinase1.
结论PUVA治疗引起的皮肤光老化皱纹形成可能与真皮成纤维细胞基质金属蛋白酶及其组织抑制剂表达失衡密切相关。
Conclusion Wrinkle formation in photoaging skin after PUVA therapy is correlated with the imbalance of expression of matrix metalloproteinases and their inhibitors of dermal fibroblasts.
目的研究基质金属蛋白酶2 (MMP 2)和金属蛋白酶组织抑制剂2 (TIMP 2)在人脑星形细胞瘤中的表达及其与病理分级的关系。
Objective to investigate the expressions of matrix metalloproteinase 2 (MMP 2) and tissue inhibitor of metalloproteinase 2 (TIMP 2) in astrocytoma and their relations to the pathological grade.
目的:研究基质金属蛋白酶-1(MMP-1)、金属蛋白酶组织抑制剂-1(TIMP-1)、增殖细胞核抗原(PCNA)在病理性瘢痕中的表达及意义。
Objective To study the significance of expression of Matrix Metalloproteinase-1(MMP-1) , Tissue Inhibitor of Metalloproteinase-1(TIMP-1) and Proliferating cell nuclear antigen (PCNA) in abnormal scar.
目的研究过量氟对大鼠切牙生长过程中基质金属蛋白酶-20(MMP-20)和基质金属蛋白酶组织抑制剂-2(TIMP-2)表达的影响,探讨氟斑牙的发病机制。
Objective To investigate the effects of overdosed fluoride on the expression of MMP-20 and TIMP-2 in rat incisor.
并且其结果是,通过这些细胞产生的组织将与患者相匹配,从而不需要免疫抑制剂来预防移植排斥反应。
And the resulting tissue made from those cells would match the patient, doing away with the need for immune suppression to prevent rejection of the transplant.
目的探讨组织金属蛋白酶抑制剂(TIMP)在食管鳞癌中的表达及其临床意义。
Objective To investigate the expression of the tissue inhibitor of metalloproteinases (TIMP) in human esophageal squamous cell carcinoma(ESCC).
目的:探讨苯那普利对糖尿病大鼠肾组织细胞周期蛋白激酶抑制剂p 21 CIP1蛋白表达的影响。
To investigate the effect of benazepril on expression of cyclin kinase inhibitor P21 CIP1 protein in renal tissue of diabetic rats.
目的探讨基质金属蛋白酶- 2 (MMP - 2),组织金属蛋白酶抑制剂- 2 (TIMP - 2)在食管鳞癌中的表达及其临床意义。
Objective to investigate the expressions of matrix metalloproteinase-2 (MMP-2) and the tissue inhibitor of metalloproteinases-2 (TIMP-2) in human esophageal squamous cell carcinoma (ESCC).
目的探讨翼状胬肉组织中细胞周期蛋白依赖性激酶抑制剂P16的表达,了解其在翼状胬肉发病机制中的作用。
Objective To observe the expression of cyclin kinase inhibitor P16 in pterygium and to investigate its effects on the pathogenesis of pterygium.
临床表现为肾小管间质损害的患者应及早行肾组织活检,明确诊断后应采用糖皮质激素联合免疫抑制剂治疗。
The patient with sarcoidosis of renal tubule involvement should undergo renal biopsy immediately, and be treated with steroids and immunosuppressant after diagnosis is established.
目的:研究基质金属蛋白酶-2 (MMP - 2)和组织基质金属蛋白酶抑制剂- 2 (TIMP - 2)在人肺癌组织中的表达及其与微血管密度(MVD)的关系。
Objective to study the expressions of metalloproteinase 2 (MMP-2) and tissue inhibitors of metalloproteinase 2 (TIMP-2) in lung cancer, and their relationships with microvessel density (MVD).
KRAS基因突变在恶性肿瘤组织中频发,可预测非小细胞肺癌分子靶向治疗的疗效和预后,针对RAS基因的分子抑制剂研究仍处于初级阶段。
KRAS mutation frequency in tumor tissue, can be predicted non-small cell lung cancer molecular targeted therapy efficacy and prognosis, and molecular inhibitors of RAS genes is still in its infancy.
目的探讨凝血酶对脑组织损害的机制,及凝血酶抑制剂水蛭素和尼莫地平对其的影响。
Objective To investigate the mechanism of brain injury caused by thrombin and the intervention effect of hirudin and nimodipine.
目的探讨基质金属蛋白酶-2 (MMP - 2)和组织基质金属蛋白抑制剂- 2 (TIMP - 2)在胃癌组织中的表达及其与侵袭程度、淋巴结转移的关系。
Objective to study the expression of MMP 2 and TIMP 2 in gastric cancer tissues and the relation to the aggregated degree, metastasis and prognosis.
目的研究基质金属蛋白酶-2(MMP-2)及其抑制物组织基质金属蛋白酶抑制剂-2(TIMP-2)在大肠癌进展中的作用及其临床意义。
Purpose To understand the relationship between the expression of MMP-2, TIMP-2 and the clinical significance in human colorectal carcinoma.
目的探讨基质金属蛋白酶-2(MMP-2)和组织基质金属蛋白抑制剂-2(TIMP-2)在大肠癌组织中的表达及其意义。
Objective To study the expression and significance of MMP-2 and TIMP-2 in colorectal carcinoma.
目的探讨基质金属蛋白酶-2(MMP-2)和组织基质金属蛋白抑制剂-2(TIMP-2)在大肠癌组织中的表达及其意义。
Objective To study the expression and significance of MMP-2 and TIMP-2 in colorectal carcinoma.
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