线粒体疾病是遗传性的，目前无法医治。
Mitochondrial diseases are hereditary, and at the moment incurable.
尽管研究的目标是阻止下一代的线粒体疾病，但此举也可能产生更糟糕的结果。
Although the study's goal is to prevent the next generation of mitochondrial disease, but this may also have worse outcomes.
在美国诊断患有线粒体疾病的人低于十万分之六，而患孤独症的为110分之一。
They are diagnosed in fewer than six per 100, 000 people in America, while autism of some sort is seen in as many as one in 110.
该技术还没有被批准用于人类生殖，但可以设想会用于防止遗传性，这类通常是致命的线粒体疾病。
The technique hasn't been approved for use in human reproduction, but could conceivably be used to prevent hereditary, often-fatal mitochondrial disease.
在美国，100000个人里不到6个人被诊断为线粒体疾病，而110个人就有一个人患自闭症。
They are diagnosed in fewer than six per 100,000 people in America, while autism of some sort is seen in as many as one in 110.
TH分子机制的研究将有助于揭示这些线粒体疾病的致病机理以及为其诊断和基因治疗提供分子依据。
To investigate the molecular mechanism of th may reveal the pathogenic mechanism of mitochondrial diseases and provide the molecular basis for diagnosis and gene therapy.
麦肯齐患有线粒体疾病，这种疾病会让人丧失大量能量，并损伤心脏、肝脏、骨骼肌、呼吸系统和大脑等部位的细胞，从而使人衰弱。
McKenzie has mitochondrial disease, a debilitating condition that deprives the body of energy and damages cells in the heart, liver, skeletal muscles, respiratory systems and brain.
线粒体dNA突变与越来越多的人类疾病有关，其中包括神经退行性疾病、糖尿病、癌症及不育症。
Mitochondrial DNA mutations are linked to a growing list of human diseases including neurodegenerative diseases, diabetes, cancer and infertility.
由共同多态现象确定的线粒体单倍群与疾病的危险因素和生存率相关。
Mitochondrial haplogroups defined by common polymorphisms have been associated with risk of disease and longevity.
近年来，有证据已经表明受到损伤的线粒体是疾病引起神经伤害的原因。
In recent years, evidence has been mounting that damaged mitochondria contribute to the neurological damage wrought by the disease.
不考虑医治任何已经存在的疾病，仅仅是移植线粒体这种行为就会带来好处。
The very act of transplanting mitochondria, regardless of any pre-existing disease, might bring benefits.
这是否意味着那些高龄者可能更易患可能伴随线粒体减少而发生的疾病？
Does that mean that those who are advanced in age are perhaps more susceptible to the diseases that may come with less mitochondria?
英国议会已经认定，如果线粒体dna存在缺陷并且会导致母体将致命性疾病遗传给孩子，那么可以将其替换。
Parliament has ruled that inherited DNA in the mitochondria can be replaced if they are defective and the cause of devastating diseases that are passed down from mothers to their children.
强化线粒体对低卡路里饮食的应激反应可以辅助机体对抗与衰老相关的疾病。
The fortification of the mitochondria in response to the stress of a much lower-calorie diet can help ward off diseases associated with aging.
研究背景——线粒体基因组的稀有变异可引发疾病。
Background - Rare mutations in the mitochondrial genome may cause disease.
在另一方面，线粒体功能障碍可导致许多神经退行性条件，以及代谢性疾病，如糖尿病。
On the other hand, mitochondrial dysfunction can lead to many neurodegenerative conditions as well as metabolic diseases such as diabetes.
线粒体有缺陷的人会患上衰弱疾病，因为他们身体组织缺少生存必须的能量，他们通常会在青年时期死去。
People with defective mitochondria suffer debilitating illness and often die young because the tissues of their bodies are starved of the energy they need to work.
方法：应用PCR技术研究了9例神经肌肉性疾病患者的血细胞或（和）肌肉组织中的线粒体DNA，共15份标本。
Method:Polymerase chain reaction(PCR) was used to investigate the mitochondrial DNA in 15 specimens from skeletal muscle and(or) blood cells of 9 patients with neuromuscular disease.
线粒体是哺乳动物的产能、供能细胞器，与生长、发育、衰老和凋亡等多种细胞事件及疾病有关。
Mitochondria, which can produce and supply energy for mammals, are involved in many cellular events of growth, development, aging, apoptosis as well as diseases.
早有已有研究证明线粒体功能障碍与多种很多其他神经系统疾病，包括帕金森病、阿尔茨海默病、精神分裂症及双相情感障碍有关。
Dysfunction in mitochondria already is associated with a number of other neurological conditions, including Parkinson's disease, Alzheimer's disease, schizophrenia and bipolar disorder.
本文就有关线粒体功能异常所引起的疾病的研究进展作一综述。
This study overviews the researches about the diseases caused by the mitochondrial dysfunction.
目的初步观察心脏瓣膜疾病与先心病患者心肌线粒体DNA缺失及其意义。
Objective to investigate primarily the deletions of myocardial mitochondrion DNA in patients with valvular heart disease and congenital heart disease and its implication.
“我们一直在努力防止孩子一出生就带有致命的疾病”，线粒体dna只是通过母体遗传。
"We're trying to prevent kids being born with fatal diseases." Mitochondrial DNA is passed down only through the female line.
这一想法可以防止有遗传缺陷的妇女，将她们线粒体d NA所携带的疾病遗传给她们的子女。
The idea is to prevent women with faults in their mitochondrial DNApassing diseases on to their children.
锰超氧化物歧化酶(SOD2)是线粒体基质酶，作为细胞内氧自由基的清除剂，SOD2与氧化应激相关的神经系统疾病密切相关。
Manganese superoxide dismutase (SOD2) is a matrix enzyme expressed in mitochondria. SOD2 is a known free radical scavenger, and has been shown to play a role in several nervous system diseases.
线粒体不再被认为是“唯一”作为蜂窝热力学转换器：越来越多的证据牵连他们在细胞信号转导，细胞增殖，衰老，疾病和死亡的重要细胞器。
Mitochondria are no longer considered "only" as the cellular thermodynamic converter: mounting evidence implicates them as key organelles in cell signaling, proliferation, aging, disease and death.
线粒体缺陷导致的疾病不仅让患者自身痛苦，还要担心自己的疾病会遗传给下一代；
Mitochondrial disease is a misery to those who have it and a fear they might pass it on to their children;
毛球标本的线粒体点突变检测率高于血液，因此在线粒体相关疾病的基因分析中具有较高的临床应用价值。
The point mutation detection rate of hair follicles was higher than that of blood. So, hair follicles have the potent clinical application value for the genetic analysis of mitochondrial diseases.
线粒体药物：线粒体代谢，疾病预防，诊断，治疗。
Mitochondrial Medicine: Mitochondrial Metabolism, Diseases, Diagnosis and Therapy.
线粒体药物：线粒体代谢，疾病预防，诊断，治疗。
Mitochondrial Medicine: Mitochondrial Metabolism, Diseases, Diagnosis and Therapy.
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