与安慰剂相比较,托纳博沙明显减少了不管有无疼痛的先兆频率。
Tonabersatsignificantly reduced the frequency of aura with or withoutpain, compared with placebo.
托纳博沙是一种抑制CSD的二乙基溴乙酰胺间隙结合阻滞剂并曾被认为是一种能防止偏头痛的的新化合物。
Tonabersat is a neuronal gap-junction blocker that inhibitsCSD and was once considered a promising new compound to preventmigraine attacks.
31位患有偏头痛先兆的病人接受了每日一次的托纳博沙治疗或每月清洗一次(随机顺序)持续三个月的安慰剂交叉治疗。
Thirty-one patients with migraine with aura received once-dailytonabersat or placebo for three months each (in random order)with a one-month washout between treatment crossover.
第二中尉安德鲁费拉拉,23日,加州托兰斯,在沙画一张地图,在介绍之前在9月14日在库纳尔省的战斗前哨蒙蒂使命。
Second Lieutenant Andrew Ferrara, 23, of Torrance, Calif., draws a map in the sand during a briefing before a mission on Sept. 14 at Combat Outpost Monti in Kunar province.
第二中尉安德鲁费拉拉,23日,加州托兰斯,在沙画一张地图,在介绍之前在9月14日在库纳尔省的战斗前哨蒙蒂使命。
Second Lieutenant Andrew Ferrara, 23, of Torrance, Calif., draws a map in the sand during a briefing before a mission on Sept. 14 at Combat Outpost Monti in Kunar province.
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