除衰老外，负重可能是纤维环细胞凋亡增加的关键因素。
Besides aging, weight bearing is probably a key factor of the increase of anulus fibrosus cells apoptosis.
负重可能是纤维环细胞凋亡增加的关键因素。
Weight-bearing is probably a key factor in the increase of annulus fibrosus cells apoptosis.
可见纤维环细胞渗透到支架中并增殖、大量的s-GAG沉积和线性胶原形成。
Infiltration and proliferation of AF cells into the scaffold and abundant deposition of s-GAG and aligned collagen was observed.
结论：除增龄外，负重是增加纤维环细胞凋亡、加重椎间盘纤维环破损和退变的重要因素。
Conclusions: Besides aging, weight bearing is probably a key factor of the increase of anulus fibrosus cells apoptosis and the degeneration of annulus fibrosus of intervertebral disc.
结论：纤维环细胞种植到有组织的、各异向性的类似纤维环样的支架上产生很好的力学特性。
Conclusion. AF cells seeded on nanofibrous scaffolds elaborated an organized, anisotropic AF-like extracellular matrix, resulting in improved mechanical properties.
结论：从未退变的椎间盘分离的纤维环细胞能在体外分化为脂肪细胞、格根包尔氏细胞、软骨细胞、神经元及内皮细胞。
Conclusions Anulus fibrosus cells isolated from nondegenerative intervertebral discs can differentiate into adipocytes, osteoblasts, chondrocytes, neurons, and endothelial cells in vitro.
分化细胞从纤维环的外缘迁移被认为是这些组织形成的可能机制。
Migration of differentiated cells from outside the intervertebral disc has been hypothesized as a possible mechanism for the formation of these tissues.
目的：观察模拟咬合压力对人牙周膜成纤维细胞环氧化酶2 (COX 2)基因表达的影响。
Objective: To investigate the influence of simulated occlusion pressure on the cyclooxygenase-2 (COX-2) gene expression in human periodontal ligament fibroblasts (HPLFs).
方法结合酶消化法和组织块培养法，体外单层培养人退变纤维环原代细胞。
Method:Primary cells of human degenerative AF were obtained through in vitro monolayer culture combined with enzyme digestion method and tissue pieces culture method.
方法结合酶消化法和组织块培养法，体外单层培养人退变纤维环原代细胞。
Method:Primary cells of human degenerative AF were obtained through in vitro monolayer culture combined with enzyme digestion method and tissue pieces culture method.
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