胶原蛋白是一种纤维化蛋白质，是生物骨组织的重要组成部分，以胶原蛋白基质的形式存在。
Collagen is a fibrous protein that is a main component of living bone tissue, in which it forms a so-called collagen matrix.
背景提高有缺陷的囊性纤维化跨膜电导调节(CFTR)蛋白的活性是囊性纤维化的一种潜在治疗。
BACKGROUND Increasing the activity of defective cystic fibrosis transmembrane conductance regulator (CFTR) protein is a potential treatment for cystic fibrosis.
目的研究纤维连接蛋白在肺纤维化中的作用。
Objective To study the roles of fibronectin played in rat pulmonary fibrosis.
方法采用酶联免疫吸附法对40例特发性肺纤维化患者和30例健康人血清基质金属蛋白酶- 9进行测定。
Methods The serum level of MMP-9 in 40 patients with IPF and 30 healthy subjects was measured by ELISA.
目的探讨基质金属蛋白酶及其抑制因子与组织纤维化的关系。
Objective to discuss the relationship between matrix metalloproteinases and its tissue inhibitors and tissue fibrosis.
背景与目的：肺纤维化是一种病因复杂的疾病，以成纤维细胞过度增殖、胶原蛋白沉积为特征。
Background and Objective: The pathogenesis of pulmonary fibrosis is complicated, it is characterized with myofibroblast hyperplasia and deposition of collagen protein.
本研究的目的是为了确定血清球蛋白和免疫球蛋白水平是否能预测丙肝复发病人的肝纤维化程度。
The aim of this study was to determine if serum globulin and immunoglobulins levels can predict the extent of fibrosis in patients with recurrent HCV infection.
结果：当归组的胶原蛋白含量低于模型组，组织病理学也显示当归能减轻肝纤维化。
Results: the level of liver collagen protein in Angelica group was than that of the model group and histopathology also show that Angelica reduced hepatic fibrosis.
方法：采用四氯化碳诱发大鼠肝损伤，辅以高脂、低蛋白复合饲料和一定浓度乙醇饮料，复制肝纤维化模型。
Methods: Experimental model of hepatic fibrosis was induced by carbon tetrachloride and supplementary high-lipid and low-protein diet and alcohol-containing beverage.
目的：观察血清层粘连蛋白（LN）对肝纤维化的诊断价值。
Objective:To investigate the diagnosis value of LN of serum to hepatofiberosis.
人们已经发现血清免疫球蛋白水平与患有慢性丙肝的非移植病人的肝纤维化程度有极大关联。
A strong association was found between serum immunoglobulins levels and hepatic fibrosis in non-transplanted patients with chronic HCV infection.
方法制备人血白蛋白免疫损伤性肝纤维化模型。
Method Immune complex-induced animal model of liver fibrosis was developed in Wistar rats.
方法分别建立高脂饮食、低脂酒精饮食、高脂酒精饮食和四氯化碳大鼠实验性脂肪肝肝纤维化模型，用免疫组织化学方法观察造模肝组织中弹性蛋白的表达。
Methods Experimental liver fibrosis rats models of were induced by high fat diet, low fat diet plus ethanol, high fat diet plus ethanol, and carbon tetrachloride subcutaneous injection, respectively.
结论：加味鳖甲煎丸对白蛋白所致大鼠免疫性肝纤维化有较好的防治作用。
Conclusion: JWBJ can effectively prevent and treat hepatic fibrosis induced by serum albumin.
表达增高的GRP78蛋白分别与血浆MDA和HCY水平以及肝纤维化指数呈显著正相关（P<0.01）。
Elevated protein expression of GRP78 was correlated positively with the content of MDA and HCY in plasma and the index of liver fibrosis (P<0.01).
目的研究基质金属蛋白酶9（MMP 9）在慢性肝病患者肝纤维化过程中的表达和动态变化。
ObjectiveTo investigate the dynamic change and expression of Matrix Metalloproteinase-9(MMP-9) in patients with chronic hepatitis B(CHB) and liver cirrhosis(LC).
传统的慢性胰腺炎胰腺纤维化指标是层粘连蛋白(LN)的含量升高及超氧化物歧化酶(SOD)活性降低。
The traditional index of pancreas fibrosis are the rising of the Laminin (LN) level and the decrease of the superoxide dismutases (SOD) activity.
此文就弹性蛋白酶在高脂血症、脂肪性肝病和肝纤维化治疗中的应用进展作一综述。
This article reviews the advance in the application of elastase to management of hyperlipoidemia, fatty liver disease and hepatic fibrosis.
根据羊毛资源和利用的现实情况，认为羊毛价值的提升，既可以充分利用改性技术来实现，也可考虑羊毛角蛋白的纤维化再生。
According to wool resource and utilization, value improvement of wool can be realized not only by modification technology but also by fiber-regeneration of wool keratin.
现将肥大细胞、蛋白酶激活受体- 2与肝纤维化的有关进展作一综述。
The following is a review of advances in mast cell, proteinase-activated receptor-2 and liver fibrosis.
目的 研究猪 胆 汁 性肝纤维化时基质金属蛋白酶2 （MMP 2 ）表达及活 性改变 ，分析其在 肝纤维化初始阶段的作用。
Objective To observe the changes of the expression of matrix metalloproteinase 2 (MMP 2) and the activity of MMP 2 in the early stage of liver fibrosis.
我们认为这种具有成纤维细胞增生因子活性的蛋白质可能就是在矽肺纤维化过程中刺激成纤维细胞增殖和胶原合成的调节因子。
We suggest that this protein may be the mediator which induces the proliferation of fibroblast and the synthesis of collagen during the process of silicosis.
结论：高氧可能导致RB蛋白磷酸化(RB灭活)，LF过度增殖最终导致肺间质纤维化。
Conclusion: the phosphorylation of RB protein can be induced by hyperoxia. Excessive proliferation of LF leads the pulmonary interstitial fibrosis.
方法采用以人血白蛋白攻击方法制备肝纤维化动物模型，放免法测定血TNF ，免疫组化法观察肝内层粘蛋白改变。
Methods The rat models of hepatic fibrosis were established by human serum albumin(HSA) injection. Serum TNF was detected by RIA method and laminin in the liver was studied by immunohistochemistry.
然而，对这种调节矽肺纤维化过程的蛋白因子的理化特性迄今还知道得很少。
The biochemical properties of the mediators involved in silicotic fibrosis, however, are not yet well defined.
贝那普利及缬沙坦可有效减轻心房纤维化和心肌缝隙连接蛋白的重构。
Benazepril and valsartan can decreased the degree of atrial fibrosis and remodeling of Gap junction connexin effectively.
结论在肝纤维化过程中伴有蛋白质合成与分解异常和糖酵解活动增强；
Conclusion (1) Li ver fibrosis is accompanied with abnormal protein synthesis and asition, a s well as the enhanced activity of glycolysis;
结论在肝纤维化过程中伴有蛋白质合成与分解异常和糖酵解活动增强；
Conclusion (1) Li ver fibrosis is accompanied with abnormal protein synthesis and asition, a s well as the enhanced activity of glycolysis;
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