在急性海马的脑片中,给予红藻氨酸盐可以以神经元依赖的方式促进S100 B分泌。
In acutely isolated hippocampal slices, kainate application increased S100B secretion in a neural-activity-dependent manner.
而且,红藻氨酸盐诱导的Gamma节律信号可以被RAGE基因缺失或抗体阻断的方式减弱。
Moreover, the kainate-induced gamma oscillations were attenuated by the genetic deletion or antibody blockade of RAGE in vivo.
目的探讨红藻氨酸诱导的慢性颞叶癫痫鼠脑海马突触重建及胶质增生与颞叶癫痫发病机制的关系。
Objective To investigate the relationship between gliosis, synaptic reorganization and the mechanism of chronic temporal lobe epilepsy induced by kainic acid.
但合成红藻氨酸诱发动物癫痫呈现规律、稳定及阶段性明显的特征,且大鼠的死亡率较天然红藻氨酸低。
However, the epileptic seizure induced by SKA showed obvious stages, regular pattern and action steady. In addition, SKA caused lower fatality than KA did.
哈勒格勃坚持认为,“这些发现有力表明,食物中的高脂肪损坏了老鼠认知记忆能力,更易受到红藻氨酸诱发产生认知功能障碍。”
"These findings show that fast food diets impaired memory acquisition in mice and made their brains more vulnerable to kainate-induced cognitive dysfunction," asserts Halagappa.
哈勒格勃坚持认为,“这些发现有力表明,食物中的高脂肪损坏了老鼠认知记忆能力,更易受到红藻氨酸诱发产生认知功能障碍。”
"These findings show that fast food diets impaired memory acquisition in mice and made their brains more vulnerable to kainate-induced cognitive dysfunction," asserts Halagappa.
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