作者在用抗体诱发动物急性溶血的方法建立的红细胞在体衰老模型的基础上,对红细胞衰老过程中的细胞密度变化进行了研究。
Changes in density of red blood cells (RBCs) during in vivo aging were studied using an animal model developed with the method of antibody inducement of acute RBC lysis.
由此提示,该红细胞衰老模型是可信的,能够用于研究红细胞的衰老过程并可以观察在衰老过程中与此相关的微观流变特性的改变。
Therefore, in can be implied that this RBC aging model is reliable, and it is favorable for the study of RBC aging process and the related microrheological changes in the time scale of days.
衰老的红细胞通过两种机制去除;它们都能使细胞的主要成分得到循环利用。
Two mechanisms exist for removal of senescent RBC; both conserve the principal constituents of the cell for reuse.
异常的和衰老的红细胞通常被脾清除。
Abnormal and aged RBC's are typically removed by the spleen.
脾具有过滤作用,清除衰老的红细胞和红细胞内含物,脾也是血小板的贮存库。
The spleen ACTS as a filter, removing old red blood cells and RBC inclusions. The spleen also ACTS as a storage area for platelets.
目的观察不同浓度牛磺酸对脂质过氧化损伤的红细胞以及自然衰老红细胞的抗氧化酶类和膜骨架蛋白保护作用,以探讨其抗氧化和抗衰老的作用机制。
Objective To observe the effect of taurine (Tau) on erythrocyte lipid peroxidative in-jury and erythrocyte survival, and to explore the protective mechanism of Tau on erythrocyte.
目的观察不同浓度牛磺酸对脂质过氧化损伤的红细胞以及自然衰老红细胞的抗氧化酶类和膜骨架蛋白保护作用,以探讨其抗氧化和抗衰老的作用机制。
Objective To observe the effect of taurine (Tau) on erythrocyte lipid peroxidative in-jury and erythrocyte survival, and to explore the protective mechanism of Tau on erythrocyte.
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