ACE抑制剂应与血管紧张素受体拮抗剂合用吗?
Should ACE Inhibitors be Combined with Angiotensin II Receptor Antagonists?
内皮素受体拮抗剂,已知对健康有益,但具体机制不明确。
Endothelin receptor antagonists are known to have health benefit but precisely why was an unknown, said Pollock, corresponding author on the study.
内皮素受体拮抗剂波生坦是治疗肺动脉高压的有效药物之一。
The endothelin receptor antagonist bosentan is one of the effective drugs for pulmonary arterial hypertension.
丙谷胺是60年代创制的治疗消化性溃疡的胃泌素受体拮抗剂。
Proglumide is a gastrin receptor antagonist synthesized in the middle of 1960s which can be used in the treatment of peptic ulcer.
我们评价了卒中后早期应用血管紧张素受体拮抗剂,替米沙坦,的作用。
We evaluated the effects of therapy with an angiotensin-receptor blocker, telmisartan, initiated early after a stroke.
对于该患者人群,这种血管紧张素受体拮抗剂还发挥了前所未有的血压控制作用。
The angiotensin receptor blocker also yielded unprecedented blood pressure control for this population of patients.
前言:目的:观察血管紧张素受体拮抗剂缬沙坦对肾病综合征大鼠的干预保护作用。
Objective: to observe the role of Angiotensin II receptor antagonist valsartan on kidney of rat with nephrotic syndrome.
血管紧张素转化酶抑制剂和血管紧张素受体拮抗剂联合用药治疗CKD是否比单药应用要好?
Is Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Combination therapy Better Than Monotherapy and Safe in Patients With CKD?
结论内皮素受体拮抗剂BQ - 123对缺血性急性肾功能衰竭早期之肾脏具有一定的保护作用。
Conclusion the endothelin receptor antagonist BQ 123 does provide a certain degree of protection for kidneys from the early stage of IARF.
目的探讨血管紧张素受体拮抗剂缬沙坦对链脲佐菌素诱导的糖尿病大鼠糖代谢、氧化应激及胰腺病理结构的影响。
Objective to assess the effects of valsartan (an angiotensin receptor blocker, ARB) on glucose metabolism, oxidative stress and pancreatic pathology in streptozotocin-induced diabetic rats.
本发明提供了具有胰高血糖素受体拮抗剂活性或反向激动剂活性的、新颖的式i化合物及其药学上可接受的盐和共晶体。
The present invention provides for novel compounds of Formula (I) and pharmaceutically acceptable salts and co-crystals thereof which have glucagon receptor antagonist or inverse agonist activity.
目的研究血管紧张素转换酶抑制剂(acei)和血管紧张素受体拮抗剂(arb)对2型糖尿病肾病患者肾功能的保护作用。
Objective to investigate the protective effect of angiotensin converting enzyme inhibitor (ACEI) and angiotensin receptor antagonist (ARB) on renal function of type 2 diabetic nephropathy patients.
瑞士最大的生物科技公司Actelion股价下跌8.6%,此前该公司生产的内皮素受体拮抗剂克拉生坦没有达到研发的主要目标。
Actelion Ltd., the largest Swiss biotechnology company, sank 8.6 percent after its clazosentan medicine didn’t meet the main goal of a study.
我们比较了血管紧张素转换酶抑制剂雷米普利、血管紧张素受体拮抗剂替米沙坦以及两药联合对有血管性疾病或高位糖尿病患者的作用。
We compared the ACE inhibitor ramipril, the ARB telmisartan, and the combination of the two drugs in patients with vascular disease or high-risk diabetes.
西他生坦服用者中出现不可逆转的肝功能衰竭及其在全球市场的召回事件,强调了对服用内皮素受体拮抗剂的患者进行肝功能监测的重要性。
The irreversible liver failure caused by sitaxsentan and its withdrawal from global markets emphasise the importance of hepatic monitoring in patients treated with endothelin receptor antagonists.
虽然小剂量的血管紧张素II注射对雄性小鼠血压没有影响,但却能显著减低雌鼠的平均动脉压,而此现象能够被血管紧张素受体拮抗剂PD123319所阻断。
Although this low dose had no effect on MAP in the male, it significantly decreased MAP in the female, and this effect was prevented by coinfusing the animals with PD123319, an antagonist of the AT2R.
如果这些结果能被将来的研究证实,那么血管加压素v 2受体拮抗剂可能将成为新的降压策略,尤其是适用黑人种群。
If these results are confirmed in further studies, then vasopressin V2 receptor antagonists might offer a novel antihypertensive strategy, especially in the black population.
本研究旨在评价血管加压素v 2受体拮抗剂的急性血流动力学效应。
This study sought to assess the acute hemodynamic effect of vasopressin V2 receptor antagonism.
束旁核内注入胆囊收缩素-A受体拮抗剂L-364,718能翻转八肽胆囊收缩素对抗电针的镇痛作用。
The injection of cholecystokinin-A receptor antagonist L-364,718 in parafascicularis nucleus could reverse the antagonism of cholecystokinin octapeptide to the effect of electroacupuncture.
结论胃泌素能增强BGC-823细胞系的运动,有促进肿瘤细胞转移的作用,而受体拮抗剂可抑制胃泌素的这种作用。
Conclusion Gastrin can aggravate the motion and metastasis of BGC 823 cells, which can be inhibited by its receptor antagonist.
但是,对轻中度收缩性HF患者,螺内酯联合血管紧张素ii受体拮抗剂对左室(LV)逆重构的价值目前还不清楚。
However, the value of combining spironolactone with an angiotensin II receptor blocker on LV reverse remodeling in mild-to-moderate systolic HF is unclear.
钙拮抗剂、肾上腺素受体阻滞剂、ACEI类一直位居前三位。
Calcium antagonists, adrenoceptor blockers and ACEI were holding first three places.
目的:观察白细胞介素6受体拮抗剂对外伤性脊髓水肿的影响,探讨白细胞介素6在外伤性脊髓水肿中的作用。
OBJECTIVE: To observe the effect of the receptor antagonist of the IL-6 on the traumatic edema of spinal cord, and explore the effect of IL-6 in the process of the edema of spinal cord.
目前已知一类称为内皮素受体A拮抗剂的药物能减少蛋白尿。
It's also known that a new class of drugs called endothelin a receptor antagonists reduce protein in the urine.
白细胞介素6受体拮抗剂治疗组细胞水肿、变性、坏死较创伤组轻。
The cellular edema, degeneration and the necrosis in the receptor antagonist of the IL-6 treated group was milder than that in the wound group.
结果:在用阿仑单抗治疗或白细胞介素-2受体拮抗剂治疗患者中的活组织检查出肾小球疾病复发率相似。
RESULTS. : Biopsy-proven glomerular disease recurrence was similar in patients induced with alemtuzumab or IL-2 receptor antagonists.
目的:研究不同剂量内皮素受体A拮抗剂FR139317对大鼠心力衰竭模型的作用。
AIM: To study the effects of a selective endothelin receptor A (ETA) antagonist FR139317 on rats with congestive heart failure.
抗高血压新药非肽类血管紧张素ii受体拮抗剂自二十世纪八十年代发现以来就受到了广泛的关注。
Antihypertensive non-peptide angiotensin II receptor antagonists have been paid much attention since it was found in 1980's.
第三章致力于吲唑脲类辣椒素受体(TRPV1)通道拮抗剂的定量构效关系(QSAR)研究。
The third chapter was devoted to the study of quantitative structure-activity relationship(QSAR) for indazolyl ureas as TRPV1 antagonists.
结果钙拮抗剂、肾上腺素受体阻滞药、血管紧张素转化酶抑制剂(acei)在用药金额、用药频度上分别占前三位。
Results the amount used DDDs of calcium antagonists, adrenergic receptor blockers and ACEI drugs were the head of three.
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