目的探讨肝非唾液酸糖蛋白受体显像与肝储备功能关系。
Objective To investigate the relation between ASGP-R developing and the reserve function of hepar.
在过去三十多年来,已报道了许多由无唾液酸糖蛋白受体介导的肝靶向药物。
During the past more than 30 years, a lot of liver targeting conjugates mediated by ASGP-R have been prepared and reported.
去唾液酸糖蛋白受体(asgpr)是哺乳动物肝细胞表面的特异性受体,肝硬化和肝癌时asgpr水平下降。
Asialoglycoprotein receptor (ASGPR) is a specific receptor of mammalian hepatocytes. Reduction in ASGPR concentration has been proven to appear in liver cirrhosis and liver cancer.
常用的受体有去唾液酸糖蛋白受体、胰岛素受体、血管内皮细胞生长因子受体、转铁蛋白受体、甘露糖受体、表皮生长因子受体、叶酸受体等。
Asialoglycoprotein receptor, transferrin receptor and receptors for lactoferrin, insulin, epidermal growth factor, folic acid and mannose have been used in receptor-mediated gene delivery.
CD 44的是一种广泛分布I型跨膜糖蛋白其在大多数细胞类型中的主要功能作为透明质酸受体。
CD44 is a widely distributed type I transmembrane glycoprotein and functions as the major hyaluronan receptor on most cell types.
流感病毒和某些副粘病毒的表面血红细胞凝集素是一种糖蛋白,可附着于含互补受体的红细胞上。
In influenza and some paramyxoviruses the surface hemagglutinin, which is a glycoprotein attaches to the B. B. C containing complementary receptor.
病毒外壳的糖蛋白通过与特异性的细胞受体结合便于侵入宿主细胞。
The glycoproteins (GP) of enveloped viruses facilitate entry into the host cell by interacting with specific cellular receptors.
病毒外壳的糖蛋白通过与特异性的细胞受体结合便于侵入宿主细胞。
The glycoproteins (GP) of enveloped viruses facilitate entry into the host cell by interacting with specific cellular receptors.
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