目的探讨缬沙坦对糖尿病大鼠肾脏糖化终末产物受体(RAGE)表达的影响，探索其肾保护机制。
Objective to investigate the effects of valsartan on the expression of receptors for advanced glycation end-products (RAGE) in kidneys of diabetic rats, and to explore its renoprotection mechanisms.
L-1剂量范围内均可有效抑制蛋白糖化终末产物的生成，当药物浓度达2.0g·L-1时其抑制作用相当于同剂量的氨基胍。
The inhibitory effects of EGB and EGS (2.0 g·L-1) on the generation of AGEs were almost the same as that of aminoguanidine at the same concentration.
L-1剂量范围内均可有效抑制蛋白糖化终末产物的生成，当药物浓度达2.0g·L-1时其抑制作用相当于同剂量的氨基胍。
The inhibitory effects of EGB and EGS (2.0 g·L-1) on the generation of AGEs were almost the same as that of aminoguanidine at the same concentration.
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