血管内皮细胞生长因子(VEGF)及其受体在肿瘤血管新生中起重要作用,阻断VEGF的生成已成为抗肿瘤治疗的新靶点。
Vascular endothelial growth factor (VEGF) and its receptor play a critical role in tumor-associated angiogenesis and have become the new targets of anti-tumor therapy.
血管内皮细胞生长因子及其受体在肿瘤新生血管形成中起重要作用,成为肿瘤治疗的新靶点。
Vascular endothelial growth factor (VEGF) and its receptor play a critical role in tumor associated angiogenesis and has become the new targets of anti tumor therapy.
目的:研究雷洛昔芬对血管内皮细胞雌激素应答元件(ERE)转录活性的影响与雌激素受体(er)亚型的关系。
Objective: to investigate the effect of Raloxifene on the estrogen responsive element (ERE) transcription activity and its relationship with estrogen receptor subtypes in vascular endothelial cells.
方法通过双重免疫组化染色,确定缓激肽b 2受体是存在于血管内皮细胞上还是存在于肿瘤细胞上。
Methods to determine whether the expression of bradykinin B2 receptor are on the vascular endothelial cell or cerebral glioma cell, double immunohistochemistry was used.
目的探讨血凝素样氧化低密度脂蛋白受体1 (LOX - 1)在氧化低密度脂蛋白(ox - LDL)诱导血管内皮细胞粘附分子表达中的作用。
Objective to investigate the effects of oxidized low-density lipoprotein receptor 1 (LOX-1) on secretion of adhesive molecules mediated by ox-LDL in human umbilical endothelial cells (HUVECs).
目的:探讨烧伤血清对心脏微血管内皮细胞内皮素受体的影响。
Objective: To investigate the effect of burned serum on the endothelin(ET) receptor in cardiac microvascular endothelial cells(CMEC).
目的观察血管内皮细胞生长因子受体嵌合蛋白对缺血性视网膜病变小鼠模型的视网膜新生血管化的抑制作用。
Objective To observe the inhibitive effects of vascular endothelial growth factor (VEGF) receptor chimeric proteins on retinal neovascularization in ischemia-induced mice model.
目的探讨淋巴管内皮细胞透明质酸受体-1染色阳性(LYVE-1+)淋巴管在大鼠肾内的分布。
Objective To investigate the distribution of intrarenal lymphatic vessels in developing rat using the lymphatic marker LYVE-1.
常用的受体有去唾液酸糖蛋白受体、胰岛素受体、血管内皮细胞生长因子受体、转铁蛋白受体、甘露糖受体、表皮生长因子受体、叶酸受体等。
Asialoglycoprotein receptor, transferrin receptor and receptors for lactoferrin, insulin, epidermal growth factor, folic acid and mannose have been used in receptor-mediated gene delivery.
推测VEGF及其受体FLK一1可能为UPR的靶基因,这可能是人脑微血管内皮细胞在应激状态下保持自身稳定性的一种机制。
VEGF and its receptor-FLK - 1 may be the target gene of UPR, suggesting a mechanism of homeostasis of HBMEC under stress.
结论雌激素水平明显影响雌鼠心脏组织和肺血管内皮细胞中雌激素受体的含量,高脂饮食可明显降低组织和细胞中雌激素受体的含量。
Conclusions the content of er in VEC and hearts are affected by serum estrogen level, and cholesterol rich diet decrease the content of er remarkably.
血管内皮细胞生长因子与其受体结合后通过酪氨酸激酶途径引起细胞的增殖及新生血管形成。
Vascular epithelial growth factor binding with its receptor leads to cell proliferation and new vascular formation by tyrosine kinase pathway.
血管内皮细胞及平滑肌细胞有多种P 2x和P 2y受体亚型表达。
The several kinds of P2X and P2Y receptor subtypes have been expressed in vascular endothelial cells and vascular smooth muscle cells.
VEGF-C主要通过其受体VEGFR-2、VEGFR-3发挥作用,是一种重要的血管、淋巴管内皮细胞调节因子。
VEGF-C and its receptor VEGFR-2/VEGFR-3 are the key players in the molecular regulation of lymphangiogenesis.
VEGF-C主要通过其受体VEGFR-2、VEGFR-3发挥作用,是一种重要的血管、淋巴管内皮细胞调节因子。
VEGF-C and its receptor VEGFR-2/VEGFR-3 are the key players in the molecular regulation of lymphangiogenesis.
应用推荐