• 内皮细胞生长因子(VEGF)及其受体肿瘤血管新生中重要作用,阻断VEGF的生成成为肿瘤治疗靶点

    Vascular endothelial growth factor (VEGF) and its receptor play a critical role in tumor-associated angiogenesis and have become the new targets of anti-tumor therapy.

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  • 内皮细胞生长因子及其受体肿瘤新生血管形成中重要作用成为肿瘤治疗靶点

    Vascular endothelial growth factor (VEGF) and its receptor play a critical role in tumor associated angiogenesis and has become the new targets of anti tumor therapy.

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  • 目的研究雷洛内皮细胞雌激素应答元件(ERE)转录活性影响雌激素受体(er)亚型关系

    Objective: to investigate the effect of Raloxifene on the estrogen responsive element (ERE) transcription activity and its relationship with estrogen receptor subtypes in vascular endothelial cells.

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  • 方法通过双重免疫组化染色,确定激肽b 2受体是存在内皮细胞还是存在于肿瘤细胞上。

    Methods to determine whether the expression of bradykinin B2 receptor are on the vascular endothelial cell or cerebral glioma cell, double immunohistochemistry was used.

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  • 目的探讨血凝素样氧化低密度脂蛋白受体1 (LOX - 1)氧化低密度脂蛋白(ox - LDL)诱导内皮细胞粘附分子表达中的作用。

    Objective to investigate the effects of oxidized low-density lipoprotein receptor 1 (LOX-1) on secretion of adhesive molecules mediated by ox-LDL in human umbilical endothelial cells (HUVECs).

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  • 目的探讨烧伤血清心脏微血内皮细胞受体影响

    Objective: To investigate the effect of burned serum on the endothelin(ET) receptor in cardiac microvascular endothelial cells(CMEC).

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  • 目的观察内皮细胞生长因子受体嵌合蛋白缺血性视网膜病变小鼠模型视网膜新生血管化抑制作用

    Objective To observe the inhibitive effects of vascular endothelial growth factor (VEGF) receptor chimeric proteins on retinal neovascularization in ischemia-induced mice model.

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  • 目的探讨淋巴内皮细胞透明质酸受体-1染色阳性(LYVE-1+)淋巴管大鼠分布

    Objective To investigate the distribution of intrarenal lymphatic vessels in developing rat using the lymphatic marker LYVE-1.

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  • 常用受体去唾液酸糖蛋白受体胰岛素受体、血管内皮细胞生长因子受体、转铁蛋白受体甘露糖受体、表生长因子受体叶酸受体等。

    Asialoglycoprotein receptor, transferrin receptor and receptors for lactoferrin, insulin, epidermal growth factor, folic acid and mannose have been used in receptor-mediated gene delivery.

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  • 推测VEGF及其受体FLK1可能UPR基因,这可能是人脑微血管内皮细胞在应激状态保持自身稳定性的一种机制

    VEGF and its receptor-FLK - 1 may be the target gene of UPR, suggesting a mechanism of homeostasis of HBMEC under stress.

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  • 结论雌激素水平明显影响雌鼠心脏组织肺血管内皮细胞中雌激素受体含量饮食可明显降低组织和细胞雌激素受体的含量。

    Conclusions the content of er in VEC and hearts are affected by serum estrogen level, and cholesterol rich diet decrease the content of er remarkably.

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  • 内皮细胞生长因子与其受体结合后通过酪氨酸激酶途径引起细胞增殖新生血管形成

    Vascular epithelial growth factor binding with its receptor leads to cell proliferation and new vascular formation by tyrosine kinase pathway.

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  • 内皮细胞平滑肌细胞多种P 2xP 2y受体亚型表达

    The several kinds of P2X and P2Y receptor subtypes have been expressed in vascular endothelial cells and vascular smooth muscle cells.

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  • VEGF-C主要通过受体VEGFR-2、VEGFR-3发挥作用,一种重要的血管淋巴内皮细胞调节因子

    VEGF-C and its receptor VEGFR-2/VEGFR-3 are the key players in the molecular regulation of lymphangiogenesis.

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  • VEGF-C主要通过受体VEGFR-2、VEGFR-3发挥作用,一种重要的血管淋巴内皮细胞调节因子

    VEGF-C and its receptor VEGFR-2/VEGFR-3 are the key players in the molecular regulation of lymphangiogenesis.

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