总有一天，我们也许能够利用端粒酶使任何细胞保持活力，使其正常工作并永久地自我复制。
Someday we may be able to take any cell and keep it alive functioning and reproducing itself essentially forever through the use of telomerase.
但当我们用化学方法分析这些细胞时，我们发现了一些非常有趣的东西，其中有一种化学物质，是一种叫做端粒酶的酶。
But when we analyze these cells chemically, we find something very interesting, a chemical in them, an enzyme called telomerase.
端粒酶是一种只在活跃分裂的细胞中产生的酶。
Telomerase is an enzyme that is produced only in cells that are actively dividing.
到目前为止，端粒酶似乎是问题的关键。
布莱克本又和格莱·德尔一起发现了端粒酶。
但是如果造出大量端粒酶的话，可以推迟细胞的死亡。
But, cell death is delayed if a lot of the enzyme telomerase is produced.
我们是否可以试着用端粒酶来处理正常的非癌细胞呢？
So why not treat regular non-cancerous cells with telomerase?
而端粒酶顾名思义，就是生成端粒的那种酶。
她惊奇地发现，端粒酶与寿命并不存在相关性。
To her surprise, she found no correlation between telomerase and longevity.
端粒酶活性的抑制可以导致细胞的衰老和死亡。
Inhibition of telomerase activity leads the cells to senescence and death.
目的：研究嵌合寡核酸对端粒酶活性的抑制作用。
Objective: To investigate the inhibitory effect of telomerase activity by chimeric oligonucleotide .
目的：探讨肾癌组织端粒酶活性和端粒长度变化。
Objective: To study the changes of telomerase activity and telomere length.
端粒酶，是一种催化延长端粒末端的反向转录酶。
Telomerase is a kind of ERT which causes catalysis and prolong the end of telomere.
胃刷落细胞的与活检组织的端粒酶活性水平是相近的。
The telomerase activity of stomach exfoliated cells was similar to that of the gastric tissue.
例如，一些科学研究表明，癌细胞利用端粒酶增长失控。
For example, some research suggests that cancer cells use telomerase to grow uncontrollably.
科学家不可能通过增加人体中的端粒酶数量来逆转人体老化的过程。
Scientists are unlikely to reverse the ageing process by boosting telomerase in people's bodies.
有氧运动还可以提高端粒酶的活性，它是一种修复端粒的酶。
Aerobic exercise may also increase the activity of telomerase, an enzyme that repairs telomeres.
这样的结果就是，除了胆固醇降低了，压力减少了，他们的端粒酶增加29%。
The results? Besides a decrease in LDL cholesterol and stress levels, they showed a 29 percent rise in telomerase.
但是，如果端粒酶非常活跃的话，端粒的长度得以维持，而细胞则能保持年轻。
But if the telomerase enzyme is very active, telomere lengths are maintained and cells are kept young.
目的探讨急性白血病端粒酶和乳酸脱氢酶活性的变化及其临床意义。
Objective To study the telomerase and serum lactic dehydrogenase activity in acute leukemia and explore its significance.
另外的遗传性的疾病能够影响皮肤和肺部同样也是由端粒酶缺失所引起。
Other inherited diseases that affect the skin and the lungs appear also to be caused by telomerase defects.
目的探讨人端粒酶逆转录酶在妊娠滋养细胞疾病中的表达及其临床意义。
Objective To investigate the expression of human telomerase reverse transcriptase in gestational trophoblastic diseases and its clinical significance.
“一些人认为端粒酶并没有那么重要，”这项研究的首席作者，白首的威廉·哈恩说。
"Some people believed that telomerase wasn't that important," says the Whitehead's William Hahn, the study's lead author.
端粒酶一直和癌症联系在一起的，而且有可能有许多其它的相关机制老化。
Telomerase has been linked with cancer, and there are likely to be many other mechanisms involved in ageing.
我很想找出它们所表达的端粒酶是什么类型的，并找出它们又是如何对抗癌的。
I'd like to find out what kind of telomerase expression they have, and find out what else they use to combat cancer.
他们的发现解释了染色体末端是怎样得到端粒的保护，而端粒是在端粒酶的作用下形成的。
These discoveries explained how the ends of the chromosomes are protected by the telomeres and that they are built by telomerase.
端粒酶激活是细胞永生化和肿瘤形成的关键步骤，其活性受到多种因素的调控。
Activation of telomerase is the critical step in cellular immortality and oncogenesis. Its activity is controled by many factors.
她分析了它们的组织来检测老鼠的端粒酶是否完全有活性，而人的有是否被抑制。
She analyzed their tissues to determine if the telomerase was fully active in them, as it was in mice, or suppressed, as it is in humans.
发现端粒酶水平与精神压力性疾病之间的关系，只是我们对这些做妈妈的人的研究结果之一。
One of the things that came out of our study of these mothers is a link between low telomerase and stress-related diseases.
发现端粒酶水平与精神压力性疾病之间的关系，只是我们对这些做妈妈的人的研究结果之一。
One of the things that came out of our study of these mothers is a link between low telomerase and stress-related diseases.
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