研究团队观察到，发生SHANK3突变的神经细胞之间的沟通受损，他们还发现脑细胞和突触（神经细胞之间的接触点）的功能和结构的可塑性发生了变化。
The research team observed impaired communication between nerve cells in the mice with the SHANK3 mutation.
在蛋白质进化到具有与皮质醇结合的新功能后产生的这些突变，如果蛋白质返回到原始状态，会导致其结构上产生冲突。
These mutations, which occurred after the protein evolved its new function to bind to cortisol, would cause structural clashes within the protein if it were returned to its ancestral state.
不过，即使结构性突变无法预测，这也不能成为虚无主义的借口。
But even if structural breaks cannot be predicted, that is no excuse for nihilism.
事实上，考虑到传统经济预测始终忽略了结构性突变，这种预测不仅难度很大，也很有用。
In fact, given that traditional economic forecasts miss structural breaks all the time, it is both difficult to achieve and useful.
亨德里的终极目标是预测结构性突变。
新达尔文主义的延伸观点认为，进化是随机突变伴随结构性的环境过滤，但看起来这些共识可能会改变。
The consensus view among neo-Darwinians continues to be that evolution is random variation plus structured environmental filtering, but it seems the consensus may be shifting.
其中的教训是，无法应对结构性突变的预测方法，会几乎无限次地失效。
The lesson is that a forecasting technique that cannot deal with structural breaks is a forecasting technique that can misfire almost indefinitely.
手工精剪的长形轮廓是情节的剪影，将结构的变形瞬间静止，突变为凝固的力量。
Long hand-cut figures are mutated into a captured form, like a combustion of anatomy.
随后运用笔者新的提法解释了历史上出现的疑难问题，最后也依笔者的思路分析并解释了上证指数结构突变的经济原因。
Finally the author use his own new idea explain knotty questions appearing in the history and further analyze and explain the economic reasons causing the structure change in stock index.
对后烟井前墙包复鳍片管结构突变处进行定性力学分析，针对性地提出相应措施及制造、安装时注意事项。
Qualitative mechanical analysis was made for special structure of back pass front wall, and relevant measures and notices for manufacturing and erection are presented.
目前，MBL的结构-功能关系未明，MBL基因突变引起调理吞噬缺损的机制不清，这些均需进一步研究予以阐明。
However, the relationship between structure and functions of MBL and the mechanisms by which MBL structure gene mutations cause opsonic deficiency are to be clarified.
经济过程中的结构突变，对非平稳时间序列的分析具有非常重要的影响。
The structure mutation during the economic process has very important influence on the analysis of non-smoothed time series.
这些结果表明，该突变不仅影响集聚蛋白诱导突触后结构的功能，也影响神经肌肉接头功能的维持。
These results indicate that the mutation does not interfere with the ability of agrin to induce postsynaptic structures but that it dramatically perturbs the maintenance of the neuromuscular junction.
目的对人类博卡病毒的基因组结构、系统进化以及突变规律进行分析。
Objective To analyze the genomic structure, phyletic evolution and mutation rules of human bocavirus.
研究者们希望，通过对该基因突变和相关蛋白结构的深入了解可以开发出有效的药物治疗来抑制突变基因的激活。
The researchers hope that understanding more about the gene's mutations and the structure of the protein may lead to drug treatments to help ensure that mutant copies of the gene are inactive.
本文简要概述了现代数学、物理学中的“耗散结构理论”、“协同论”和“突变论”的基本内涵和特点。
This paper briefly sums up the basic connotation and characters of the dissipation structure theory, the cooperation theory and the sudden change theory in modern mathematics and physics.
对于带缝运行的水工混凝土结构，用小波分析和突变理论相结合的方法，建立裂缝转异诊断模型。
An abnormality diagnosis model was developed for hydraulic concrete structures operating with cracks occurring in their bodies by use of the wavelet analysis and cusp catastrophe theory.
关于结构突变问题大致可以分为有关单位根的结构突变问题和协整的结构突变问题。
Structure change can be classified into unit root related structure change and cointegration structure change.
酪氨酸576和酪氨酸577处于激酶结构域的激活环，这些残基的突变减弱FAK的催化活性（6）。
Tyr576 and Tyr577 lie in the activation loop of the kinase domain, and mutation of these residues reduces FAK catalytic activity (6).
探讨具有水平连接刚度突变特征的钢筋混凝土结构的一般力学特点与动力反应分析方法。
General mechanic differences and methods of dynamic response analysis of RC structure characterized by abrupt change in horizontal connection stiffness are discussed.
文章给出了基于小波分析的信号奇异性检测理论，通过对突变信号进行小波分析可以发现结构的损伤情况。
The signal singularity detection theory based on wavelets analysis is given. Through the study of those singularity, the damage situation of the structure may be discovered.
在转换层附近、塔楼与裙房连接附近以及设备层附近结构刚度有不同程度的突变。
Lateral stiffness of the structure varies significantly near the transfer floor, between the podium and the upper towers and near the story containing equipment.
目的对广东地区汉族人群的甘露聚糖结合凝集素结构基因第一外显子第54位密码点突变（GGC54GAC）进行初步筛查。
Objective To screen the point mutation at the codon 54(GGC54GAC) in the first exon of the mannan binding lectin (MBL) gene in Hans from Guangdong.
本文是将突变理论应用于工程结构的动力稳定性的一个尝试。
This paper represents an attempt at the application of catastrophe theory to the dynamic stability of engineering structures.
本文是将突变理论应用于工程结构的动力稳定性的一个尝试。
This paper represents an attempt at the application of catastrophe theory to the dynamic stability of engineering structures.
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