目的：探讨检测人类白细胞抗原(HLA)和群体反应性抗体(PRA)对肾移植高敏受者的临床意义。
OBJECTIVE To investigate human leukocyte antigen (HLA) matching and panel reactive antibody (PRA) titer in highly sensitized recipients of renal allograft.
为了进一步解释群体反应性抗体(pra)的免疫球蛋白性质及其对异基因肾移植的潜在威胁。
To further analyze immunoglobulin (Ig) properties of panel reactive antibodies (PRA) and their potential harmful effects on allogeneic renal transplants.
MICA抗体的存在与同种异体肾移植排斥反应有相关性。
The presence of MICA antibodies was associated with renal-allograft rejection.
目的建立治疗性单克隆抗体溶液持续器官灌注模型，应用抗大鼠树突状细胞单克隆抗体(WZD)降低大鼠移植脾的免疫原性。
Objective To reduce immunogenicity of the donor spleen, a rat model of continuous perfusion of graft was established with therapeutic anti dendritic cells monoclonal antibody (WZD).
抑瘤性实验发现，单链抗体处理组移植瘤生长速率与PBS组类似。
Tumor inhibition experiment showed that the tumor growth in the antibody treatment group was similar to that of the PBS control group.
结论ELISA方法在筛选肾移植受者群体反应性抗体检测中显示出良好的应用前景。
Conclusion the testing results indicate that ELISA method has a better prospect for the selection of PRA in renal transplantation recipients.
结论ELISA方法在筛选肾移植受者群体反应性抗体检测中显示出良好的应用前景。
Conclusion the testing results indicate that ELISA method has a better prospect for the selection of PRA in renal transplantation recipients.
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