探索两电极电压钳技术在非本征离子受体研究中的应用。
Explore the application of the two-electrode voltage-clamp technique in the studies of the extrinsic ionotropic receptor.
合成了一种新的携带有葸荧光基团和硫脲基的阴离子受体2,通过核磁氢谱、质谱和元素分析等表征了它的结构。
A novel anion receptor 2 bearing anthracene flurophore and thiourea was synthesized and identified by 1H NMR MS, IR and elemental analysis.
探索两电极电压钳技术在外源性促离子型受体表达研究中的应用。
Explore the application of the two-electrode voltage-clamp technique in the studies of the extrinsic ionotropic receptor expressed.
分子生物学自始就丰富了我们对离子通道和信号转导中重要的受体认识。
Initially molecular biology enriched our understanding of ion channels and receptors important for signaling.
钙存储于内质网(ER),在内质网内与钙离子结合分子伴侣如钙联接蛋白和钙网蛋白缓冲,并通过IP3受体通道释放(1)。
Calcium is stored in the endoplasmic reticulum (er), where it is buffered by calcium binding chaperones such as calnexin and calreticulin, and is released via the IP3 Receptor channel (1).
另外,非去极化肌松药还可以改变烟碱样受体的类脂膜,改变其离子通道。
In addition, non depolarizing neuromuscular blocking drugs may alter the lipid membrane around the nicotinic cholinergic receptors, changing the properties of the ion channel.
结论氨基酸受体门控性离子通道电流改变在肝性脑病发生中起一定作用。
Conclusions the changes of the amino acid receptor gated ion channel currents play an important role in the pathogenesis of hepatic encephalopathy.
蛋白耦联受体本身并不具备离子通道;它们通过G蛋白分子介导通道的激活。
G-protein coupled receptors do not have ion channels as part of their structure; they affect channels by activation of intermediate molecules called G proteins.
探讨氨基酸受体门控性离子通道电流改变在肝性脑病(HE)发生中的作用。
Objective to explore the effects of the changes of the amino acid receptor gated ion channel currents on the pathogenesis of hepatic encephalopathy (he).
酸感应离子通道(ASIC)是质子激活的受体,它们存在于很多人体组织和器官中,在中枢和周围神经系统中尤其丰富。
Acid-sensing ion channels (ASICs) are proton-activated receptors that are present in many human tissues and organs, and are particularly abundant in the central and peripheral nervous system.
嘌呤能P 2x7受体激活可导致大鼠视网膜神经节细胞死亡和胞内钙离子浓度升高。
The activation of purinergic P2X7 receptor can cause rat retinal ganglion cell death and the increase of intracellular calcium.
方法用膜片钳记录仪在体外培养的不同时期,记录大鼠海马神经元GABA-A受体离子通道全细胞通道电流、电导的变化。
Methods: The patch clamp was used to record the changes in average whole cell current and the conductance of GABA-A receptor on cultured hippocampal neurons in different developing stages.
香草酸受体是瞬时受体电位离子通道家族中的成员,为治疗疼痛的新靶点。
As the member of transient receptor potential family of ion channels, vanilloid receptor is the new target against pain.
因为神经递质和受体结合(配位)启动了这些离子通道, 所以他们被称为配位门通道,以区别于电压门通道。
Because the binding of the neurotransmitter (ligand) to the receptor activates these ion channels, they are called ligand-gated channels to distinguish them from voltage-gated channels.
通过牛磺酸对神经细胞、基因、激素、离子、受体、酶类等的作用,对其影响学习记忆方面的研究现状作出综述。
The present studies of taurine were reviewed by its effects to nerve cell, gene, hormone, ion, receptor and enzyme etc.
提示胰岛素是通过作用于胰岛素分泌颗粒上的IP3受体而使钙离子外排的。
The results suggest that insulin could induce calcium ions release from secretory granules through the activation of IP3 receptors on granules.
本文综述了全麻药对脊髓内神经元、神经元间的突触传递、相关受体及离子通道的作用。
This paper reviews the actions of general anesthetics on neurons, synaptic transmissions, related receptors as well as ion channels in the spinal cord.
星型胶质细胞虽然没有动作电位,但是可以表达多种受体和离子通道,并且以细胞内钙波传递的方式来响应各类刺激。
Although lacking action potentials, astrocytes express various receptors and ion channels and exhibit intercellular propagating Ca2 + waves in response to various stimuli.
这表明钠离子通道阻断剂在与受体相互作用时具有共同的结构特征和作用方式,同时也为探讨受体结构提供了有价值的信息。
Studies of these results show that the sodium channel blockade has common structural features and way of action when interact with the receptor, thus leading to identical biological effect.
酪氨酸激酶型受体、G蛋白偶联受体和离子通道型受体是细胞表面三类主要受体。
Receptor tyrosine kinases (RTK), G protein-coupled receptors (GPCR) and ion channel receptors are main cell surface receptors.
结论通过细胞膜上L型钙离子通道进行跨膜信号传递,NPY-Y1受体介导促血管平滑肌细胞增殖作用。
Through the signal pathway of L-type calcium channel on the cytomembrane, NPY-Y1 receptor could increase the proliferation of SMCs.
目的探讨双极电压钳技术在促离子型受体研究中的应用。
Objective To explore the application of the two-electrode voltage-clamp technique in the studies of the extrinsic ionotropic receptor expressed by living oocytes.
锌离子随着神经元的活动从突触前膜的囊泡中释放到突触间隙,对突触内受体进行调控。
This divalent cation is released from presynaptic vesicles into the synaptic cleft upon neuronal activity and acts as a modulator of many ligand-gated ion channels.
低温可以通过质膜流动性的改变被质膜感知,也可以通过质膜上的钙离子通透性通道、组氨酸激酶、受体激酶和磷酸酯酶感知。
Cold can be perceived by plasma membrane either due to changes in membrane fluidity or with the help of sensors like Ca 2+ permeable channels, histidine kinases, receptor kinases and phospholipases .
化学、生物传感器也可用于抗体、酶、细菌、受体、DNA、表面等离子共振体、红外线光谱等检测方法中。
Sensors and biosensors are also available using antibodies, enzymes, bacteria, receptors, DNA, surface plasmon resonance or infrared spectroscopy.
化学、生物传感器也可用于抗体、酶、细菌、受体、DNA、表面等离子共振体、红外线光谱等检测方法中。
Sensors and biosensors are also available using antibodies, enzymes, bacteria, receptors, DNA, surface plasmon resonance or infrared spectroscopy.
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