问题关键在于找到正确的诱导干细胞分化成心脏细胞,神经细胞,制造胰岛素的细胞或者其他细胞的生长因子的正确方法。
The key lay in finding just the right recipe of growth factors and nutrients to induce a stem cell to become a heart cell, a neuron, an insulin-making cell or something else.
EGR家族成员的表达可被生长因子诱导,EGR1的表达可被神经生长因子(NGF)诱导(1,2)。
The expression of EGR family members is induced by growth factors, with EGR1 expression being induced by NGF (1, 2).
目的:探讨肿瘤坏死因子相关凋亡诱导配体(TRAIL)联合化疗药物治疗神经母细胞瘤(NB)的作用及其可能机制。
Objective: To explore the role of tumor necrosis factor-related apoptosis-inducing ligand(TRAIL) combined with chemotherapeutic agents in treating neuroblastoma(NB) and the possible mechanism.
目的研究多发性骨髓瘤(MM)细胞脑源性神经营养因子(BDNF)的表达水平及其与MM细胞诱导的血管新生的关系。
Objective To investigate the expression of brain-derived neurotrophic factor (BDNF) in multiple myeloma (MM) cells and the correlation between BDNF and MM angiogenesis.
目的:观察神经生长因子(NGF)诱导PC 12细胞周期的变化,以建立体外神经元样细胞周期的研究模型。
Objective: to observe the effect of nerve growth factor (NGF) on cell cycle in PC12 cells, and to establish a cell cycle model of neuron-like cell in vitro.
为研究低氧诱导因子- 1 (HIF - 1)在小鼠胚胎神经胚形成阶段的时空表达规律,探讨HIF - 1在胚胎神经系统发生和发育过程中的作用。
To investigate the spatiotemporal expression of hypoxia-inducible factor-1 (HIF-1) during murine neurulation and explore the role of HIF-1 in the embryonic development of the nervous system.
这和最近的研究是一致的,该研究表明卵母细胞成熟抑制因子能诱导用TNF处理的人类神经多肽的凋亡而不从线粒体中释放出来(7)。
This is in accord with a recent study that shows Omi can induce apoptosis in human neutrophils treated with TNF- without being released from the mitochondria (7).
这些发现提示,DME可能通过对脑缺血的抗氧化作用及刺激神经营养因子的合成,对脑缺血诱导的脑损伤有治疗作用。
These findings suggested that DME may be of value in the treatment of ischemia-induced brain damage through stimulation of antioxidant activity and neurotrophic factor synthesis.
目的:观察多因子联合诱导和分步诱导方案诱导大鼠脂肪组织源性干细胞体外分化为神经元样细胞的可行性。
OBJECTIVE: to explore the feasibility of inducing rat ADSCs into neuron-like cells with a new scheme and medium containing multiple factors.
方法采用眼镜蛇毒因子特异激活血清补体,诱导人神经母细胞瘤细胞SH-SY5Y损伤。
Methods A model of neuronal injury was established on SH-SY5Y cells through activation of complement by cobra venom factor, an alternative pathway-specific activator.
我们总结神经祖细胞和胶质祖细胞移植能够产生兴奋性和抑制性神经元,神经营养因子能够诱导移植物来源神经元轴突向指定方向生长。
We concluded that NRP/GRP grafts can be used to produce excitatory and inhibitory neurons, and neurotrophin gradients can guide axonal growth from graft-derived neurons toward putative targets.
结论人脐血单核细胞体外经细胞因子诱导分化培养,可生成大量的DC。DC体外可促进T细胞对神经母细胞瘤细胞的杀伤效应。
Conclusions Human cord blood mononuclear cells could be served as a better source of DC, which can promote the capacity of initiating T cell-dependent anti neuroblastoma tumor immune responses.
应用寡核苷酸诱导的定点突变和PCR技术对人脑源性神经营养因子基因进行突变,并完成了测序鉴定。
Human brain derived neurotrophic factor gene was used as template for oligonucleotide based site directed mutagenesis and PCR.
应用寡核苷酸诱导的定点突变和PCR技术对人脑源性神经营养因子基因进行突变,并完成了测序鉴定。
Human brain derived neurotrophic factor gene was used as template for oligonucleotide based site directed mutagenesis and PCR.
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