GFAP蛋白是星形胶质细胞的细胞骨架成分。年龄增长、脑损伤、神经退行性疾病都会使GFAP蛋白水平增高。
GFAP levels normally rise with age, brain injury, and neurodegenerative disease.
研究者们接下来通过特异性结合细胞表面蛋白质的抗体将神经胶质瘤细胞分成不同的类型。
The researchers then sorted glioma cells into different types using antibodies that stick to specific proteins on a cell's surface.
这其中,蛋白分子神经胶质素- 1 (neuroligin - 1)起了重要作用,因其促进了神经接触位置(神经元突触)必要的发育成熟过程。
The protein molecule neuroligin-1 plays an important role in this as it stimulates the necessary maturation processes at the contact sites (synapses) of the nerves.
这种生物标志物被称之为神经胶质纤维酸性蛋白。这种蛋白质只能在脑震荡患者的脑部和神经系统中被发现。
The biomarker is called glial fibrillary acidic protein, or GFAP. The protein is only found in the brain and nervous system after a person suffers a concussion.
目的了解新生鼠缺氧缺血性脑损伤(HIBD)时大脑皮质神经元特异性烯醇化酶(nse)和胶质纤维酸性蛋白(GFAP)的变化。
Objective To observe the change of neuron-specific enolase (NSE) and glial fibrillary acidic protein (GFAP) in neonatal rats' cerebral cortex with hypoxic-ischemic brain damage (HIBD).
目的:探讨来源于人胚胎脑室下区(SVZ)的胶质纤维酸性蛋白(GFAP)阳性神经前体细胞系向神经元分化的潜能。
Objective: to investigate the ability of human GFAP positive neural progenitor cell line from the subventricular zone (SVZ) to differentiate into neurons.
层粘连蛋白的表达主要分布于血管基膜和胶质膜,即是神经胶质和间叶组织间的接合部分。
The laminin was distributed mainly in the vascular basement membrane and glial membrane, which was the joint section between neuroglial and mesenchymal tissues.
结果:毛果芸香碱惊厥持续状态模型鼠病理损伤特点为神经元坏死、细胞凋亡、凋亡蛋白表达增多,胶质细胞增生。
RESULTS: Neuron necrosis, apoptosis, increase of apoptosis protein expression and proliferation of glial cells were the characteristics of pathological injury in the pilocarpine induced se models.
将经过蛋白质治疗的带有正常神经胶质功能标记的唐氏模型鼠与未经治疗的唐氏模型鼠混合。
Mice treated with the proteins had markers of healthy glial function that were missing in the untreated Down's mice.
近年来,一种位于突触前膜、囊泡膜及神经胶质细胞膜上的糖蛋白—神经递质转运体逐渐成为神经科学界研究的热点。
Recently, transporter, that is a sort of protein located in the presynaptic membrane, vesicle membrane and glia cell membrane, has been the study hotspot of neuroscience.
目的探讨从神经胶质瘤细胞中提取热休克蛋白抗原肽复合物(HAC)的方法。
Objective To investigate the methods for extraction of heat shock protein antigen complex (HAC) from glioma cells.
目的探讨饮酒致大鼠海马区神经胶质细胞内胶质纤维酸性蛋白(gfap)和s- 100B蛋白表达的改变,并观察饮酒对大鼠学习、记忆功能的影响。
Objective: To investigate the expression change of GFAP and S-100B protein in rat hippocampus lead by alcohol, and observe the influence of alcohol with study and memory.
目的:探讨烧伤后慢性应激大鼠海马神经元微管相关蛋白- 2 (MAP - 2)和神经胶质细胞胶质纤维酸性蛋白(GFAP)表达的变化。
Objective: To study the expressions of microtubule associated protein-2 (MAP-2) and glial fibrillary acidic protein (GFAP) in hippocampus of rats with depression after burn.
移植细胞能够在视网膜神经上皮层组织片下存活,表达胶质纤维酸性蛋白,并与邻近组织建立联系。
The transplanted cells, which labeled by BrdU and expressed GFAP, could survive under the retinal explants and make connection with neighbor cells.
免疫组化鉴定神经元烯醇化酶(NSE)、神经丝蛋白(NF)、胶质纤维酸性蛋白(GFAP)的表达。
Neuron-specific enolase(NSE), neurofilament(NF), and glial fibrillary acidic protein(GFAP) were detected by immunohistochemistry.
将新生大脑中的这些调节蛋白加入胶质细胞,确实可开启神经 蛋白的表达。
These regulator proteins are introduced into glial cells from the postnatal brain, which indeed respond by switching on the expression of neuronal proteins.
S100 B是一类酸性钙结合蛋白,在中枢神经系统中主要存在于胶质细胞,是星形胶质细胞活化的标志之一。
S100B is a class of acid calcium-binding protein. It mainly exists in neuroglial cells in the central nervous system, and it is one of the signs of astrocyte activation.
目的:研究血小板活化因子(PAF)对神经元活力及星形胶质细胞胶质纤维酸性蛋白(GFAP)表达的影响。
AIM: to observe the effect of platelet-activating factor (PAF) on cultured neuronal viability and glial fibrillary acidic protein (GFAP) expression in cultured astrocytes.
脑损伤后,神经蛋白聚糖在胶质瘢痕中的表达明显增加,据认为可阻止轴突再生。
After brain damage, the expression of neurocan obviously increases again in the glial scar. It is considered that neurocan can prevent the regeneration of axon.
结果在手术切除的病灶组织中,除一些增生性的星形胶质细胞同时具上述三种蛋白的阳性标记外,在一些异形的神经元内同时还存在有MDR1和MRP的阳性表达。
Results An over expression of immunoreactivities for MDR 1 and MRP was found at both reactive astrocyte and some giant dysplastic neurons, while the overexpression of GFAP co…
用细胞免疫荧光标记星形胶质细胞特异性的神经胶质酸性蛋白,星形胶质细胞纯度达95%以上的细胞备用。
Glial fibrillary acidic protein, the specific protein of astrocyte, was labeled by cell immunofluorescence method. The purity of astrocyte achieved to 95% was considered to be used in the study.
神经节细胞对s- 100蛋白呈阴性反应,雪旺细胞和胶质细胞对s - 100蛋白呈强阳性反应。
Neurons were negative to S-100protein, while Schwann cell and gliocyte were strongly positive.
NECL1恢复表达的U251细胞有向星形胶质细胞分化的趋势,星形胶质细胞标志蛋白神经胶质纤维酸性蛋白的表达上调。
The U251 cells was differentiated potentially to astrocytes, and glial fibrillary acidic protein was up-regulated after the restoration of the NECL1 expression.
目的研究低氧预适应对海马神经元和星形胶质细胞在急性缺氧暴露时的葡萄糖转运蛋白的活性和基因表达的影响。
Objective To explore the effect of hypoxic preconditioning on the activity and gene expressions of glucose transporters in the cultured rat hippocampal neurons and astrocytes under anoxic condition.
目的研究低氧预适应对海马神经元和星形胶质细胞在急性缺氧暴露时的葡萄糖转运蛋白的活性和基因表达的影响。
Objective To explore the effect of hypoxic preconditioning on the activity and gene expressions of glucose transporters in the cultured rat hippocampal neurons and astrocytes under anoxic condition.
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