目的观察肝细胞生长因子对神经干细胞向神经元细胞方向分化的作用。
Objective to explore the effect of hepatic growth factor on the neuronal differentiation of the neural stem cells.
结论:类缺血处理后的皮质神经元对外源性神经干细胞的分化有促进作用,并能促进其向神经元分化。
CONCLUSION: Cortical neuronal cells injured in ischemia like conditions can significantly promote the differentiation of exogenous NSCs and make them differentiated into neurons more.
结论:硝普钠可以抑制脊髓源性神经干细胞的增殖、诱导脊髓源性神经干细胞向神经元的分化。
Conclusions is Sodium nitroprusside can inhibit the proliferation and promote the differentiation of spinal neural stem cells into neuronal but not glial cells in vitro.
目的:利用NGF诱导的PC12细胞分化模型,探讨ERK通路、P53/P21蛋白和CDK5/P35蛋白在神经元分化过程中的可能作用及相互关系。
Objective: To investigate the roles and relationships among ERK pathway, P53/P21 and CDK5/P35 during neuronal differentiation using a differentiative model of PC12 cells induced by NGF.
大鼠肾上腺嗜铬细胞瘤细胞PC12具有神经元样分化的潜能,在PC12细胞中转染并过量表达NECL2能够诱导细胞发生神经元样分化。
NECL2 distributed in cell body and protuberance of primary culture neuron. The rat adrenal gland tumor cell line PC12 can be induced into neuronal differentiation.
该所的科学范围涉及细胞周期,细胞分化,肿瘤形成,染色体生物学,神经元引导,和干细胞生物学等多个领域。
Its scope of the science spans such diverse areas as cell cycle progression, cell differentiation, oncogenesis, chromosome biology, neuronal guidance and stem cell biology.
本发明还提供通过给予所述患者治疗有效量的本发明化合物来诱导干细胞分化成神经元细胞的方法。
The invention further provides a method for inducing stem cell differentiation into neuronal cells, by administering to the patient a therapeutically effective amount of a compound of the invention.
通过诱导分化的对照实验获得神经元分化比例最高的方法。
The approach with highest neuronal differentiation rate was confirmed through control induction experiments.
本发明涉及能够刺激神经元细胞分化、神经细胞存活、以及与记忆和学 习有关的神经元可塑性的肽序列。
The present invention relates to peptide sequences capable of stimulating neuronal cell differentiation, neural cell survival and neuronal plasticity associated with memory and learning.
这些结果表明丙戊酸诱导了C6胶质瘤细胞向神经元样显型方向的特异分化。
These results indicate that VPA induces a specific differentiation of C6 cells toward a neuronal-like phenotype.
这些结果表明丙戊酸诱导了C6胶质瘤细胞向神经元样显型方向的特异分化。
These results indicate that VPA induces a specific differentiation of C6 cells toward a neuronal-like phenotype.
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