结论:硝普钠可以抑制脊髓源性神经干细胞的增殖、诱导脊髓源性神经干细胞向神经元的分化。
Conclusions is Sodium nitroprusside can inhibit the proliferation and promote the differentiation of spinal neural stem cells into neuronal but not glial cells in vitro.
方法采用细胞培养技术、免疫细胞化学方法观察新生大鼠皮层神经干细胞向胆碱能神经元定向分化的时空变化。
Observation the space-time change of cortex nerve stem cell in newborn rat orientation differentiation to cholinergic neuron by cell cultured and immunocyte chemistry methods.
此外,尚有安全性方面的顾虑,因为有迹象表明从人干细胞分化来的多巴胺神经元可能引发肿瘤生长。
There have also been safety concerns, with signs that dopamine neurons developed from human stem cells can trigger the growth of tumors.
目的观察肝细胞生长因子对神经干细胞向神经元细胞方向分化的作用。
Objective to explore the effect of hepatic growth factor on the neuronal differentiation of the neural stem cells.
结论:从未退变的椎间盘分离的纤维环细胞能在体外分化为脂肪细胞、格根包尔氏细胞、软骨细胞、神经元及内皮细胞。
Conclusions Anulus fibrosus cells isolated from nondegenerative intervertebral discs can differentiate into adipocytes, osteoblasts, chondrocytes, neurons, and endothelial cells in vitro.
神经突的形成过程被称为神经突生成,是神经元(中枢神经系统的主要细胞成分)细胞分化的第一步。
The formation of neurites, a process called neuritogenesis, is the first step in the differentiation of neurons, the basic information cells of the central nervous system.
结论:实验结果揭示人胎脊髓中可能存在不止一种神经营养活性成分,对GABA神经元的活性和分化起营养作用。
Conclusion: the results suggest that there are more than one neurotrophic substances in human fetal spinal cord that exerted neurotrophic effects on survival and differentiation of GABAergic neuron.
而HNG - E则为发生转化的神经干细胞系,但能在RA诱导下向多巴胺能神经元分化。
HNG-E cells were characterized as transformed neural stem cells, and can be differentiated into dopaminergic neurons by ra induction.
在加有鸡胚骨骼肌提取液的培养基诱导下,能向胆碱能神经元方向分化。
These neural stem cells could be induced to differentiate into cholinergic neurons by using embryonic chick skeletal muscle extract.
结论:大鼠胎血和骨髓msc的细胞形态、生物学特性无明显差别;两者诱导分化为神经元样细胞的能力无显著差异。
Conclusion: The evident difference is not found in biological characteristics and ability of differentiation into neuron-like cells between rat fetal blood and bone marrow-derived MSCs.
分化培养中加入碱性成纤维细胞生长因子能够提高胆碱能神经元分化的比例。
The addition of basic fibroblast growth factor in differentiation culture could increase the proportion of cholinergic neurons.
有了这项技术,就可以弄清为了重建神经元之间联系并使之成为一个功能网络,神经突是如何的形成并分化的。
This technological breakthrough opens the door to understanding how neurites form and differentiate to regenerate neuronal connections and give rise to a functioning network.
目的:利用NGF诱导的PC12细胞分化模型,探讨ERK通路、P53/P21蛋白和CDK5/P35蛋白在神经元分化过程中的可能作用及相互关系。
Objective: To investigate the roles and relationships among ERK pathway, P53/P21 and CDK5/P35 during neuronal differentiation using a differentiative model of PC12 cells induced by NGF.
神经干细胞具有分化成神经元、少突胶质和星形胶质细胞的功能且能不断自我增殖。
Neural stem cells have the potential to differentiate into neurons, astrocytes, and oligodendrocytes and to self-renew sufficiently to provide the Numbers of cells in the brain.
目的研究神经干细胞向胆碱能神经元定向分化后对脊髓横断损伤的修复作用。
Objective To observe the effects of transplanting cholinergic neurons after inducing neural stem cells on treating spinal cord injury.
目的探讨人脐血单个核细胞体外向神经元样细胞定向诱导分化的条件。
Objective To probe the conditions for inducing human cord blood monocytes to differentiate into neuron-like cells.
目的:探讨骨髓基质细胞条件培养液诱导中脑神经干细胞分化为高比例神经元的机制。
Objective: To investigate the effects of bone marrow stromal cell conditioned medium on differentiation of mesencephalic neural stem cells into neurons.
结论:类缺血处理后的皮质神经元对外源性神经干细胞的分化有促进作用,并能促进其向神经元分化。
CONCLUSION: Cortical neuronal cells injured in ischemia like conditions can significantly promote the differentiation of exogenous NSCs and make them differentiated into neurons more.
目的探讨铝对大鼠神经干细胞向神经元样细胞分化的影响。
Objective To investigate the effects of aluminum on differentiation of rat neural stem cells in vitro.
目的寻求无血清、无饲养层细胞存在的情况下,胚胎干细胞向多巴胺能神经元定向诱导分化的最佳条件。
Objective to explore the optimal condition of direct differentiation into dopaminergic neurons of embryonic stem cells in serum-free and feeder layer cell free medium.
目的:比较大鼠胎血和骨髓中间充质干细胞(MSC)体外培养过程中的生长特性及体外诱导两者向神经元样细胞分化的异同。
Objective: to compare the growth characteristics and differentiation into neuron-like cells of mesenchymal stem cells (MSCs) derived from rat fetal blood with MNCs from rat bone marrow in vitro.
目的探讨体外培养的骨源性间充质干细胞向神经元样细胞的分化。
Objective to explore to differentiation of mesenchymal stem cells (MSCs) derived from bone into neuron-like cells.
大鼠肾上腺嗜铬细胞瘤细胞PC12具有神经元样分化的潜能,在PC12细胞中转染并过量表达NECL2能够诱导细胞发生神经元样分化。
NECL2 distributed in cell body and protuberance of primary culture neuron. The rat adrenal gland tumor cell line PC12 can be induced into neuronal differentiation.
目的:观察不同浓度抗坏血酸对神经干细胞向多巴胺能神经元分化的影响。
OBJECTIVE: to investigate the effects of ascorbic acid on the differentiation of neural stem cells into DA neurons in vitro.
目的:探讨来源于人胚胎脑室下区(SVZ)的胶质纤维酸性蛋白(GFAP)阳性神经前体细胞系向神经元分化的潜能。
Objective: to investigate the ability of human GFAP positive neural progenitor cell line from the subventricular zone (SVZ) to differentiate into neurons.
分化后的细胞表达神经元细胞、质细胞和少突胶质细胞的特异性抗原。
Mature neural cells after differentiation could express specific antigens of neuron, astrocyte and oligodendrocyte.
目的通过促分化因子的调节作用对神经干细胞向胆碱能神经元的定向分化进行探讨研究。
To study nerve stem cell directional differentiation to cholinergic neuron by adjusting action of promote differentiation factors.
方法:胚胎大鼠脊髓神经细胞原代培养,倒置相差显微镜下进行细胞记数和显微测量,观察神经元存活和生长分化的状况。
Methods: Using primary nerve cell culture, we observed the survival and growth of spinal cord neurons with phase-contract microscope.
目的探讨纹状体组织对胚胎干细胞向多巴胺能神经元分化的定向诱导作用,及其细胞来源和诱导方式。
Objective To explore the inductive effect of striatal tissue on mouse embryonic stem cells and further analyse the cell source and inductive pattern of this inductive effect.
目的探讨纹状体组织对胚胎干细胞向多巴胺能神经元分化的定向诱导作用,及其细胞来源和诱导方式。
Objective To explore the inductive effect of striatal tissue on mouse embryonic stem cells and further analyse the cell source and inductive pattern of this inductive effect.
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