通过诱导分化的对照实验获得神经元分化比例最高的方法。
The approach with highest neuronal differentiation rate was confirmed through control induction experiments.
目的:观察不同浓度抗坏血酸对神经干细胞向多巴胺能神经元分化的影响。
OBJECTIVE: to investigate the effects of ascorbic acid on the differentiation of neural stem cells into DA neurons in vitro.
形态学初步证实ERK信号转导通路可能与神经干细胞向神经元分化有关。
The morphological results showed that ERK signal transduction might be related to the differentiation of NSCs into neurons.
分化培养中加入碱性成纤维细胞生长因子能够提高胆碱能神经元分化的比例。
The addition of basic fibroblast growth factor in differentiation culture could increase the proportion of cholinergic neurons.
而HNG - E则为发生转化的神经干细胞系,但能在RA诱导下向多巴胺能神经元分化。
HNG-E cells were characterized as transformed neural stem cells, and can be differentiated into dopaminergic neurons by ra induction.
结论:类缺血处理后的皮质神经元对外源性神经干细胞的分化有促进作用,并能促进其向神经元分化。
CONCLUSION: Cortical neuronal cells injured in ischemia like conditions can significantly promote the differentiation of exogenous NSCs and make them differentiated into neurons more.
目的探讨纹状体组织对胚胎干细胞向多巴胺能神经元分化的定向诱导作用,及其细胞来源和诱导方式。
Objective To explore the inductive effect of striatal tissue on mouse embryonic stem cells and further analyse the cell source and inductive pattern of this inductive effect.
目的:观察神经干细胞纤维蛋白凝胶支架移植治疗阿尔茨海默病(AD)模型的效果以及神经元分化的情况。
Objective: to observe the effect of transplanting neural stem cells and fibrin glue (FG) to treat AD model rats and the differentiation of neurons.
目的:探讨来源于人胚胎脑室下区(SVZ)的胶质纤维酸性蛋白(GFAP)阳性神经前体细胞系向神经元分化的潜能。
Objective: to investigate the ability of human GFAP positive neural progenitor cell line from the subventricular zone (SVZ) to differentiate into neurons.
前言: 目的:观察神经干细胞纤维蛋白凝胶支架移植治疗阿尔茨海默病(AD)模型的效果以及神经元分化的情况。
Objective: To observe the effect of transplanting neural stem cells and fibrin glue(FG) to treat AD model rats and the differentiation of neurons.
目的:利用NGF诱导的PC12细胞分化模型,探讨ERK通路、P53/P21蛋白和CDK5/P35蛋白在神经元分化过程中的可能作用及相互关系。
Objective: To investigate the roles and relationships among ERK pathway, P53/P21 and CDK5/P35 during neuronal differentiation using a differentiative model of PC12 cells induced by NGF.
利用血液去培育干细胞获得成功以后,朱敏设法诱导它们分化成三种细胞系:先是骨骼和软骨细胞,然后是肌细胞,再是神经元。
Using blood to nourish and grow the stem cells, Zhu managed to induce them to differentiate into three lineages: first bone and cartilage, then muscle, and then neuron.
目的观察肝细胞生长因子对神经干细胞向神经元细胞方向分化的作用。
Objective to explore the effect of hepatic growth factor on the neuronal differentiation of the neural stem cells.
方法采用细胞培养技术、免疫细胞化学方法观察新生大鼠皮层神经干细胞向胆碱能神经元定向分化的时空变化。
Observation the space-time change of cortex nerve stem cell in newborn rat orientation differentiation to cholinergic neuron by cell cultured and immunocyte chemistry methods.
神经突的形成过程被称为神经突生成,是神经元(中枢神经系统的主要细胞成分)细胞分化的第一步。
The formation of neurites, a process called neuritogenesis, is the first step in the differentiation of neurons, the basic information cells of the central nervous system.
此外,尚有安全性方面的顾虑,因为有迹象表明从人干细胞分化来的多巴胺神经元可能引发肿瘤生长。
There have also been safety concerns, with signs that dopamine neurons developed from human stem cells can trigger the growth of tumors.
结论:从未退变的椎间盘分离的纤维环细胞能在体外分化为脂肪细胞、格根包尔氏细胞、软骨细胞、神经元及内皮细胞。
Conclusions Anulus fibrosus cells isolated from nondegenerative intervertebral discs can differentiate into adipocytes, osteoblasts, chondrocytes, neurons, and endothelial cells in vitro.
目的:探讨骨髓基质细胞条件培养液诱导中脑神经干细胞分化为高比例神经元的机制。
Objective: To investigate the effects of bone marrow stromal cell conditioned medium on differentiation of mesencephalic neural stem cells into neurons.
结论:硝普钠可以抑制脊髓源性神经干细胞的增殖、诱导脊髓源性神经干细胞向神经元的分化。
Conclusions is Sodium nitroprusside can inhibit the proliferation and promote the differentiation of spinal neural stem cells into neuronal but not glial cells in vitro.
结论:实验结果揭示人胎脊髓中可能存在不止一种神经营养活性成分,对GABA神经元的活性和分化起营养作用。
Conclusion: the results suggest that there are more than one neurotrophic substances in human fetal spinal cord that exerted neurotrophic effects on survival and differentiation of GABAergic neuron.
目的从胚胎大鼠脊髓神经管中分离神经上皮干细胞并诱导其向多巴胺能神经元方向分化。
Objective to isolate neuroepithelial stem cells from the spinal cord neural tube of the embryonic rat and induce them to differentiate into dopaminergic neurons.
结论GDNF能促进PD模型大鼠黑质内神经元前体细胞向多巴胺能神经元方向分化。
Conclusion GDNF might be able to promote the neuronal precursors in the SN of PD rats to differentiate into DA neurons.
目的探讨体外培养的骨源性间充质干细胞向神经元样细胞的分化。
Objective to explore to differentiation of mesenchymal stem cells (MSCs) derived from bone into neuron-like cells.
结论:大鼠胎血和骨髓msc的细胞形态、生物学特性无明显差别;两者诱导分化为神经元样细胞的能力无显著差异。
Conclusion: The evident difference is not found in biological characteristics and ability of differentiation into neuron-like cells between rat fetal blood and bone marrow-derived MSCs.
用鸡胚骨骼肌提取液,诱导神经干细胞向胆碱能神经元方向分化。
Embryonic chick skeletal muscle extract was used to induce the differentiation of the neural stem cells into cholinergic neurons.
结论:胚胎神经上皮细胞多数为神经干细胞,黑质内移植后可以存活并分化为多巴胺能神经元。
Conclusion: Present findings demonstrate that embryonic neural stem cells dissociated from neural tube can survive and differentiate into dopamine neurons.
在加有鸡胚骨骼肌提取液的培养基诱导下,能向胆碱能神经元方向分化。
These neural stem cells could be induced to differentiate into cholinergic neurons by using embryonic chick skeletal muscle extract.
结果提示:视网膜母细胞瘤来源于神经外胚层上皮,向神经元和光感受器方向分化。
The results suggested that retinoblastoma originated from the retinoblast with potential of differentiation into photoreceptors and neurons.
纹状体中移植细胞主要分化为神经元和星形胶质细胞。
In striatum, the labeled cells differentiated into neurons and glias.
纹状体中移植细胞主要分化为神经元和星形胶质细胞。
In striatum, the labeled cells differentiated into neurons and glias.
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