目的合成碳青霉烯类抗生素美罗培南。
Aim To synthesize meropenem trihydrate, a carbapenem antibiotic.
本课题概述了碳青霉烯类抗生素的研究进展，并设计合成了比阿培南的侧链中间体。
This paper studied some of the highlights in the progress of the research of carbapenem antibiotics, designed and mainly synthesized branched chain intermediate of biapenem.
由于碳青霉烯类抗生素原料合成难度大、工艺复杂，该类药物在我国上市的品种不多。
Because carbapenems are difficult to synthesize antibiotics, complex, such drugs listed in the breed.
NDM-1可存在于不同种类的细菌中，甚至对最强大的抗生素之一、碳青霉烯类抗生素也能产生抗药性。
NDM-1 can exist inside different bacteria, and it makes them resistant to even the most powerful antibiotics - carbapenems.
这种"超级病菌"能够产生名为NDM-1的酶，而NDM-1可存在于不同种类的细菌中，甚至对最强大的抗生素—碳青霉烯类抗生素也能产生抗药性。
The "superbug" make an enzyme called NDM-1, whic can exist inside different bacteria, and it makes them resistant to even the most powerful antibiotics - carbapenems.
这种"超级病菌"能够产生名为NDM-1的酶，而NDM-1可存在于不同种类的细菌中，甚至对最强大的抗生素—碳青霉烯类抗生素也能产生抗药性。
The "superbug" make an enzyme called NDM-1, whic can exist inside different bacteria, and it makes them resistant to even the most powerful antibiotics - carbapenems.
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