这是一个竞争的毒蕈碱型乙酰胆碱受体拮抗剂。
It is a competitive antagonist for the muscarinic acetylcholine receptor.
包括直接兴奋毒蕈碱受体的药物和(胆碱酯酶抑制剂)。
Included here are drugs that directly stimulate muscarinic receptors and drugs that potentiate cholinergic activity, usually by slowing the breakdown of acetylcholine (CHOLINESTERASE INHIBITORS).
目的探讨正常幼龄豚鼠眼巩膜组织毒蕈碱受体五种亚型的表达。
Objective to investigate the expression of 5 muscarinic receptor subtypes in the scleral tissue of immature guinea pigs.
目的探讨山莨菪碱对运动终板膜上烟碱型乙酰胆碱受体的作用。
Objective to find out whether anisodamine (ANI) ACTS on nicotinic type of acetylcholine (ACh) receptor in the membrane of end plate.
抗胆碱药作用于气道平滑肌上的特定毒蕈碱受体，以抑制迷走张力。
Anticholinergics act by blocking muscarinic receptors in the smooth muscle of the airways and inhibiting vagal tone.
实验结果提示，某些四氢异喹啉类生物碱的药理作用可能与M -胆碱受体有关。
It can be inferred that some pharmacological effects of tetrahydroisoquinolines are probably related to M-cholinergic receptors.
人晶状体上皮细胞系内肌醇1，4，5-三磷酸受体和兰尼碱受体的表达和作用。
Expression and role of inositol 1,4,5-trisphosphate receptor and ryanodine receptor in a human lens epithelial cell line.
目的探讨毒蕈碱样乙酰胆碱受体(M受体)在缺氧复合梭曼中毒脑损伤中的作用。
Objective to explore the roles of muscarinic acetylcholine receptor (m receptor) in rat brain injuries after soman intoxication combined with hypoxia.
这些药物，毒蕈碱受体阻断大多被视为有害的副作用，如便秘，镇静，记忆障碍，事业。
With these medications, the muscarinic receptor blockade was mostly viewed as the cause of unwanted side effects, such as constipation, sedation, and memory impairments.
目的观察牛磺酸对东莨菪碱所致模型小鼠学习记忆及对其脑组织M胆碱受体结合力的影响。
Effect of Taurine on learning-memory ability and M-cholinergic receptor in dementia model mice induced by scopolamine;
背景：毒蕈碱受体在调节逼尿肌细胞收缩过程中起重要作用，其受体亚型M3R直接介导逼尿肌细胞收缩。
BACKGROUND: Muscarine receptor plays a key role in adjusting contraction of detrusor muscle cell, and M3R, isoforms of its receptor, can mediate contraction of detrusor muscle cell directly.
帕金森病的这些症状可以通过减少脑内乙酰胆碱介导的神经传递而缓解，但很少有人注意到脑干细胞毒蕈碱受体的作用。
Symptoms associated with Parkinson's can be helped by reducing acetylcholine-mediated neurotransmission in the brain, but little work has focused on brainstem muscarine receptors in this disease.
另取肠段按毛果芸香碱、阿托品或SCS、再毛果芸香碱的顺序给药，观察嗜酸乳杆菌scs对M型胆碱受体的作用。
The effect of SCS on M cholinoceptor was observed by adding in order pilocarpine, atropine or SCS, and pilocarpine.
目的研究M3受体激动剂毛果芸香碱对离体大鼠心肌缺血再灌注损伤的保护作用。
OBJECTIVE To investigate the protective effects of M3 receptor agonist pilocarpine on myocardial ischemia-reperfusion injury in isolated rat hearts.
我们研究了胸腺激肽与胸腺细胞的温育时间、不同剂量及酸、碱、热和酶处理后的胸腺激肽对PNA受体的影响。
The effect of thymic peptide hormone on the changes of PNA receptors on the cell surface of mouse thymocyte was found to be both concentration and time dependent.
非特异性5-HT受体阻断剂麦角新碱（MS）对睡眠无直接影响，但可完全阻断5-HTP的促睡眠效应。
Microinjection of methlysergide(MS), an antagonist of 5-HT receptor, into the hippocampus, had no direct effect on sleep, but abolished the SWS-promoting effect of 5-HTP completely.
TRPV 1受体不仅对热起反应也对辣椒碱有反应，成分是由辣椒胡椒辛辣素产出。
TRPV1 receptors not only respond to heat but also to capsaicin, the compound that creates the spicy kick in chili peppers.
方法：采用复合因素建立脾虚证模型，在此基础上通过阻断胆碱能受体的方法给小白鼠颈后皮下注射东莨菪碱建立脾虚痴呆模型。
Methods: the animal model was established in composite factors, with injecting scopolamine into subcutaneous part of nuchal region of rat, to block the cholinergic receptor.
应用受体的放射配基结合分析法测定出甜菜碱对大鼠肝细胞膜表皮生长因子受体（EGF）及其酪氨酸蛋白激酶（TPK）有显著的结合抑制作用。
Using radioligand of binding assay of receptors determinates that betaine can inhibit the binding of EGF receptor with EGF and affect the TPK activity conspicuously.
结论：苦参碱能诱导C6胶质瘤细胞的凋亡，其机制与死亡受体途径和线粒体途径的众多基因有关。
Conclusion: Matrine can induce C6 glioma cell apoptosis and the mechanism might be related to a number of genes involved in death receptor pathway and mitochondrial pathway.
上述结果提示东莨菪碱引起呼吸抑制可能与阻断呼吸中枢m 1受体有关。
The above results suggest that respiratory inhibition induced by scopolamine may be related to blocking M1-R of the respiratory center.
科学家发现小鼠吸收尼古丁后导致了斯里兰卡肉桂碱2型受体（RYR2）的表达。
The scientists found that nicotine administration to mice induces the expression of a gene called type 2 ryanodine receptor (RyR2).
目的：研究乌头类有毒中药毒性成分乌头碱、新乌头碱和次乌头碱对心肌细胞膜受体作用的机制。
Objiective:To research the mechanisms of the venenons constituent of the Aconitum—aconitine, mesaconitine, hypaconitine on the membrane receptor of myocardial cell.
团队后来检验了小鼠的脑组织，它缺乏TRPV1受体并发现长时程抑郁缺失，应用辣椒碱也不能引发突触改变。
The team then tested brain tissue from mice that lacked TRPV1 receptors and found that long-term depression was absent - and that applying capsaicin still couldn't elicit the changes to the synapses.
实验表明，小檗碱未影响胰岛素的分泌与释放，也未影响肝细胞膜胰岛素受体的数目与亲和力，小檗碱的作用可能为受体后效应。
Experiments showed that berberine neither affected insulin secretion or release, nor affected the capacity and affinity of insulin receptor of liver membrane.
结果：GABAA受体拮抗剂荷包牡丹碱能逆转GABA摄取抑制剂3-哌啶甲酸引起的血压升高，GABAB受体拮抗剂CGP 35348则不能；
Results: GABA uptake inhibitor nipecotic acid-induced increase of MAP was blocked by GABAA receptor antagonist bicuculline, but not by GABAB antagonist CGP 35348;
山莨菪碱具有阻断胆碱能受体，解除血管痉挛，改善局部血流的作用。
Anisodamine has the effect of blocking cholinergic receptor, relieving vasospasm and improving regional circulation.
山莨菪碱具有阻断胆碱能受体，解除血管痉挛，改善局部血流的作用。
Anisodamine has the effect of blocking cholinergic receptor, relieving vasospasm and improving regional circulation.
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