结论：尼尔雌醇可以抑制IL6基因表达，从而抑制破骨细胞骨吸收，减少骨量丢失。
Conclusion: Nylestriol can inhibit expression of IL 6 mRNA, reduce osteoclastic bone resorption and decrease loss of bone mass.
目的探讨喂饲补肾中药大鼠血清在成骨细胞破骨细胞培养体系中对破骨细胞骨吸收功能的影响。
Objective To investigate the effects of serum from kidneytonifing traditional Chinese drugfed rats on the osteoclasts in the osteoblastosteoclast coculture system.
结果：高龄人群成骨细胞骨形成作用和破骨细胞骨吸收作用对骨骼的影响都逐渐下降，但表现出不同的特点。
RESULTS:Osteoblasts and osteoclasts changed with different features in the elderly population, although their influences on bone formation and bone resorption were declined gradually.
目的探讨血小板衍生生长因子(PDGF) -BB在成骨细胞-破骨细胞培养体系中对破骨细胞骨吸收功能的影响。
Objective to investigate the biological effects of platelet-derived growth factor (PDGF) -bb on the osteoclasts in the osteoblast-osteoclast co-culture system.
结果raw264.7细胞TRAP染色阴性，单核或2个核，能表达破骨细胞表型和功能基因，无骨吸收功能。
Results RAW264. 7 cells show TRAP-negative with monocyte or 2 nucleus, expressing osteoclast phenotypic and functional genes without capability of absorbing bone tissue.
骨吸收功能短暂激活，主要表现为：破骨细胞数量一度增加，而其泌酸和蛋白酶功能基本得以保持。
The transient activation of bone resorption function, presented as the temporary increase of osteoclasts number and mostly maintenance of its function of excreting acid and protease.
石骨症的特征是破骨细胞功能出现障碍，使骨吸收减慢，导致骨再建缺陷。
Summary of Background Data. Osteopetrosis is characterized by osteoclast dysfunction, impaired bone resorption, and poor bone remodeling.
目的：研究阿仑膦酸盐通过凋亡抑制破骨细胞性骨吸收的作用。
Objective: to study the inhibiting effect of alendronate on the apoptosis of osteoclasts.
结论双膦酸盐对破骨细胞性骨吸收有明显的抑制作用。
Conclusions Osteoclast-mediated bone resorption was inhibited by the bisphosphonate administration.
抑制破骨细胞的分化成熟就能有效控制骨的吸收。
The inhibition of the differentiation and maturity of osteoclast will inhibit bone resorption.
提示APD具有较强的直接抑制破骨细胞性骨吸收的作用，对骨质疏松症可能有一定的疗效。
It is suggested that APD could directly suppress osteoclastic bone resorption and might be effective in osteoporosis.
绝经后骨质疏松症是一种代谢性骨疾病，是绝经后妇女雌激素水平降低导致破骨细胞的骨吸收大于成骨细胞的骨形成作用。
Postmenopausal osteoporosis is a kind of metabolic osteopathy, whose cause is that bone absorption of osteoclast is more forceful than osteogenesis of osteoblast.
卵巢功能正常和FSH接近正常浓度一半的小白鼠，由于破骨细胞的破骨作用引起骨吸收作用的减弱，从而使骨量增加。
In mice with normal ovaries and approximately half the normal concentration of FSH, bone mass increased due to a decline in bone resorption by cells known as osteoclasts, which break down bone.
如果能够控制破骨细胞的产生从而控制牙槽骨的吸收，就可以达到控制牙齿移动的目的。
If the alveolar bone resorption can be controlled through inhibition of osteoclast, the anchorage teeth movement will be effectively managed.
TWEAK在一定程度上能延长破骨细胞的生存时间并能显著促进破骨细胞的骨吸收功能。
TWEAK can prolong the life time of osteoclasts to some extent and can promote the function of osteoclasts in vitro.
结果成骨细胞呈饱满的梭形，ALP染色阳性；破骨细胞呈多核，TRAP染色阳性，可以吸收骨质形成骨陷窝。
Results Osteoblasts are full fusiform, ALP stain positive cells, while osteoclasts are multinuclear and TRAP stain positive, with the ability of forming bone lacuna;
运用甲苯胺蓝染色法观察含药血清对成骨细胞-破骨细胞共育体系中OC形成骨吸收陷窝的影响。
Determine the effect of BBC-containing serum on absorption of lacuna formed by oc in osteoblast and osteoclast co-culture system by toluidine blue staining.
结论ICD具有较强的直接抑制破骨细胞性骨吸收的作用，对骨质疏松症可能有一定的治疗作用。
The effect of ICD was stronger than that of APD. Conclusion ICD directly suppresses osteoclastic bone resorption and may be effective in osteoporosis.
建立了成骨细胞和破骨细胞共同培养体系，探讨了白细胞介素-1（IL1）促进骨吸收的作用机理。
We compared th effect of interleukin-1 (IL1) alone or with osteoblasts on osteoclastic bone re-sorption.
结果RANK的阳性信号出现在乳牙根吸收面的破牙细胞和接近牙胚的牙槽骨陷窝中的破骨细胞、恒牙胚的成牙本质细胞和前期牙本质中。
Result RANK positive signals were observed on the odontoclasts in the absorbed lacunae of deciduous teeth roots and osteoclasts in the alveolar bone near.
目的研究国产因卡磷酸钠（ICD）对破骨细胞性骨吸收的作用。
Objective To study the effects of domestic incadronate(ICD) on osteoclastic bone resorbing lacunae.
目的研究国产因卡磷酸钠（ICD）对破骨细胞性骨吸收的作用。
Objective To study the effects of domestic incadronate(ICD) on osteoclastic bone resorbing lacunae.
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