结论RAW264．7具有破骨细胞特征性基因表达谱，是一种较好的破骨前体细胞模型。
Conclusions RAW264. 7 cell could be used as a preferable preoste-oclast model in respect of its osteoclast characteristic gene expression profile.
一旦由包括VEGF在内的促成熟细胞因子活化后，破骨细胞的前体细胞可以分化成为成熟的破骨细胞，破坏骨组织，给肿瘤细胞的生长腾出空间。
When activated by maturation factors including VEGF, the pre-osteoclasts differentiated into mature osteoclasts and chew up bone tissue, providing the tumor new space to grow.
一旦由包括VEGF在内的促成熟细胞因子活化后，破骨细胞的前体细胞可以分化成为成熟的破骨细胞，破坏骨组织，给肿瘤细胞的生长腾出空间。
When activated by maturation factors including VEGF, the pre-osteoclasts differentiated into mature osteoclasts and chew up bone tissue, providing the tumor new space to grow.
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