背景:人类白细胞抗原(HLA)半相合造血干细胞移植由于供源广泛,在儿科具有广阔的应用前景。
Background: HLA haploidentical bone marrow is a potential source of doner for children for its availability.
背景:移植后造血干细胞的顺利归巢是单倍相合骨髓移植成功的关键。
BACKGROUND: Successful homing of haemopoietic stem cells is the key step for the success of haploidentical bone marrow transplantation.
目的探讨HLA半相合外周血造血干细胞移植(PBSCT)急性白血病的疗效及安全性。
Objective To explore the efficiency and safety of HLA partially mismatched peripheral blood stem cell transplantation (PBSCT) for treatment of acute leukemia.
方法:25例急性白血病患者接受HLA相合同胞的异基因外周血造血干细胞移植,其中急性髓系白血病20例,急性淋巴细胞白血病5例。
METHODS: a total of 25 patients with acute leukemia received HLA-identical sibling allo-PBSCT. All cases included 20 cases with acute myeloid leukemia and 5 cases with acute lymphocytic leukemia.
方法:25例急性白血病患者接受HLA相合同胞的异基因外周血造血干细胞移植,其中急性髓系白血病20例,急性淋巴细胞白血病5例。
METHODS: a total of 25 patients with acute leukemia received HLA-identical sibling allo-PBSCT. All cases included 20 cases with acute myeloid leukemia and 5 cases with acute lymphocytic leukemia.
应用推荐