随着更多相关变异得到识别,研究人员也就能够清楚精神分裂症的原因,而不会钉死在一个或几种基因,或一种生理途径上。
As more related variants are identified, it has become clear to researchers that the cause of schizophrenia will never be pinned on one or several genes or one physiological pathway.
研究报告发表在1月9日出版的《美国人类学遗传》杂志上,研究小组描述了neuregulin3基因的变异影响着和精神分裂症及相关的妄想症。
Reporting in the Jan. 9 issue of the American Journal of Human Genetics, the team describes how a variation in the neuregulin 3 gene influences delusions associated with schizophrenia.
他们还需要弄清楚所有这些基因变异是如何与健康和疾病相关联的。
They still need to figure out how all those genetic variables relate to health and disease.
有一种蛋白据信与哮喘相关,科学家在研究哈特人的相关信息时发现了一种编码这种蛋白的变异基因。
A protein had previously been linked to asthma. And scientists studied data from Hutterites to find a variation in the gene that encodes the protein.
他补充说,挑战在于这一相关性研究的下一步,即弄清楚这些变异基因如何可能导致分子老化过程的功能性变化。
He added that the challenge was to next move beyond this correlative study to figure out how these gene variations may lead to functional changes that contribute to the molecular process of aging.
这些变异改变了三个与眼睛相关基因的活动,这三个基因控制着眼球的生长,并且确保进入眼睛的光线在视网膜上被转换成电脉冲。
These alter the activity of three genes that control the growth of the eyeball and ensure light entering the eye is converted into electrical pulses in the retina.
人们也进行了测试,看看他们与阿尔茨海默氏症相关的APOE基因是否变异。
People were also tested to see if they had a variant of the APOE gene linked with Alzheimer's disease.
果然不出所料,胸腺嘧啶的变异同样和吸烟者发生肺癌的机会呈正相关。
Not surprisingly, having the t variant also correlates with the chance of a smoker getting lung cancer.
或许最令人惊讶的是,初步分析显示百岁老人与对照组有同样多的疾病相关的遗传变异。
Perhaps most surprisingly, preliminary analysis showed that centenarians had just as many genetic variants linked to diseases as did people in the control group.
根据来自非洲、亚洲和欧洲的270个人的基因分析资料,科学家们绘制了新的“复制数量变异”图,它将改变科学家们寻找与疾病相关的遗传因子的方式。
The new CNV map – compiled from 270 individual genomes of people with African, Asian and European ancestry – will change the way in which scientists search for genes involved in disease.
DRD4基因的7r变异体是一种多巴胺受体基因。它已经被证明与追求新奇的个性相关。
The 7r variant of DRD4, a dopamine receptor gene, had previously been associated with novelty seeking.
下一步将是测序部分候选基因,以找出长寿相关的变异。
The next step will be to sequence some of the candidate genes in order to figure out what the longevity-linked variants do.
那些出现在某个家庭的扩张型心肌病的病例与一些影响肌肉细胞的变异相关。然而,很多病例是原因未明的。
Those cases of DCM that occur in certain family groups are associated with a number of mutations affecting muscle cells. However, most cases are of unknown cause.
群体分析表明,该多态性位点与耐湿性呈极显著相关,它所解释的耐湿性表型变异为13 9%。
This locus showed significant correlation to waterlogging tolerance of the population, explaining 13 9% of total phenotypic variation.
但是,研究者解释,癌风险和这些变异相关的程度会依个体的家族史而变化。
But, researchers explained, the extent of cancer risk associated with such mutations can vary depending on an individual's family history.
相比正常人,有MC1R基因变异的人更多的患有口腔医疗相关的焦虑并害怕相关疼痛。
People with the MC1R gene variant had more dental care-related anxiety and fear of dental pain than those without the gene variant.
以云南引种的46株元宝枫的果实为研究材料,对其果实的9个性状变异和各性状间的相关性进行了分析研究。
Taking 46 Acer truncatum introduced to Yunnan as the study materials, the variance of 9 fruit characters and the correlation between different characters were analyzed.
但是这个特性形成了被社会文化组成塑造和决定的人性,并且与它们众多的变异相关。
But the specific shape into which this humanness is molded is determined by those sociocultural formations and is relative to their numerous variations.
这种变异是遗传性神经母细胞瘤发病的最根本原因,和死亡率很高的非遗传性神经母细胞瘤也密切相关。
The mutations are the primary drivers behind the inherited form of the disease, and are also strongly associated with a non-inherited form that carries a particularly high risk of death.
先前发现与B12最高水平相关的基因变异可以保护胃免受诺沃克病毒的感染,和幽门螺旋杆菌引起的溃疡。
The gene variant associated with the highest B12 levels has previously been determined to protect the stomach from infection by the Norwalk virus and ulcer-causing H. pylori bacterium.
在一个线粒体基因中具备密切相关的如此一个高度保守和变异的混合区域,使得COI基因尤为适合用于进化研究。
Such a mix of highly conserved and variable regions so closely associated in a mitochondrial gene make the COI gene particularly useful for evolutionary studies.
事实上,一些与更大的敏感性相关遗传变异也和有较少的负面情绪相关。
In fact, some of the genetic variants linked with greater sensitivity are also associated with less negative emotionality.
该方法是以区域化变量为核心和理论基础,以空间相关和变异函数为基本工具的一种数学地质方法。
With regionalized variable as its kernel and theory base, the method is a kind of mathematical geological method using spatial correlation and variation functions as its basic tools.
根据动物试验得到的结果,研究者推论人类涉及BH 4调控的基因特殊变异与对疼痛的不同反应相关。
As a result of the animal studies, the researchers hypothesized that particular variations of human genes involved in the regulation of BH4 might be associated with different responses to pain.
由于过去人们对习语变体的相关研究大多停留在变异类型的划分归类上,因而相对忽视了对它们的功能研究。
Since much past work related to idiom variations is only concerned with some broad categorization of different types of variations, their functions are relatively neglected.
因此,良好的鼻整形效果是建立在外科医生对鼻部解剖结构及其变异,以及手术对相关解剖结构改变有深入而透彻的认识基础之上的。
Therefore excellent results can only be obtained if the surgeon has a thorough knowledge of nasal anatomy, its variations, and the surgical relevance of altering its structures.
病例4 ~6虽有胆管变异,但无相关并发症的发生。
Case 4 ~ 6 present anatomic variation of bile duct, but no related complications occurred.
在这项针对幼儿的研究中,研究者发现失眠症与心率变异性受损密切相关。
In a study of young children, researchers showed that insomnia symptoms were consistently associated with impaired heart variability measures.
很多糖尿病相关基因变异存在于DNA序列的“旧”区域,表明人类进化而易于发生糖尿病。
Many of the diabetes-linked variations seem to be the "older" version of the DNA sequence, suggesting that human beings evolved to be susceptible to diabetes.
结论:脓毒症患者血糖变异性与住院死亡率直接相关。
Conclusions: Glucose variability is independently associated with hospital mortality in septic patients.
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