目的利用胶原构建皮肤组织工程支架。
OBJECTIVE: To build the trestle of tissue engineering for skin with the collagen.
皮肤替代产品最为成熟，最近有好几个组织工程(产商)将在全球市场经营这些材料。
Skin replacement products are the most advanced, with several tissue-engineering wound care materials currently on the market worldwide.
理想的组织工程皮肤应该是包含表皮与真皮组织、具有完整皮肤生理功能的复合皮。
The ideal tissue-engineered skin should consist of cuticle and dermal tissues as well as compound skins of complete physiological function.
真皮替代物是组织工程皮肤的重要组成部分。
Dermal substitute is an important component of the tissue engineering skin.
应用于组织工程，例如皮肤替换、骨替换以及人造血管和瓣膜的替换，就是胶原的重要用途之一。
This article reviews the main applications of collagen in tissue engineering including skin replacement, bone substitutes and artifical blood vessels and valves.
结果：成功构建了具有表皮层和真皮层的组织工程皮肤。
Results Succeeded in culturing tissue engineering skin with dermis and epidermis.
目的研究体外培养的人表皮角质形成细胞的生物学特性，为构建组织工程皮肤提供技术参数。
Objective To study the biological characteristics of in vitro cultured human keratinocytes for providing the technical parameters in constructing tissue engineering skin.
兰格在组织工程方面也有颇多建树，包括发明了诸如人工皮肤在内的生物组织合成替代品等。
Langer has also made innovations in tissue engineering, including synthetic replacement for biological tissues such as artificial skin.
近年来，组织工程皮肤的研究已成为当前研究的热点之一。
The investigation of tissue engineering skin has become one of the hot sports in recent yeas.
目的探索红外热像扫描技术在组织工程皮肤移植修复中应用的可能性。
Objective To study the application possibility of infrared-ray scan technique in observing the graft effect of tissue engineering skin.
目的检测组织工程皮肤的生物活性及免疫原性，探讨临床可行性。
AIM to observe the immunogenicity and bioactivity of tissue engineering skin and to determine its possibility on clinic.
目的观察体外培养组织工程皮肤的生物学活性。
Objective To investigate the bioactivity in the in vitro cultured tissue engineering skin.
结论构建的组织工程皮肤模型能判定化学品的刺激性，可以尝试用于化学品刺激性的检测。
Conclusion This cultured tissue engineering skin model has been well established, which may apply as a primary test for the irritation of chemicals to the skin.
本实验为复合壳多糖组织工程皮肤临床应用提供了有力的实验依据。
This animal study provides experimental evidence for clinical application of the composite chitosan tissue engineered skin.
本实验为复方壳多糖组织工程皮肤临床应用提供了有力的实验依据。
This animal study provides experimental evidence for clinical application of composite chitosan tissue engineered skin.
目的：探讨组织工程皮肤动物移植实验的效果。
OBJECTIVE: To investigate the effects of tissue engineered artificial animal skin in animal grafting experiment.
结论利用壳多糖作为基质网架制备的组织工程化人工皮肤具有合成和分泌胶原蛋白的能力。
Conclusion the tissue engineering artificial skin which is reconstructed by chitosan as scaffold has the ability of synthesis and secretes collagen.
目的利用组织工程原理探讨修复全层皮肤缺损的理想方法。
Objective To investigate an ideal approach of skin repair using skin tissue engineering principle.
结论：复合法所得原代复合细胞接种于人工真皮，体外培养6天可大量增殖，初步获得组织工程皮肤。
Conclusion: The complex cells, inoculated into artificial dermis, cultured 6 days in vitro, showed proper proliferation. Tissue engineering skins were constructed preliminary.
组织工程化皮肤研究一直是当前研究的热点，目前尚无特别有效的皮肤替代物应用于临床。
Tissue engineering skin is a hot spot recently, but up to now there are no effective skin substitute which can be extensively applied in clinic.
组织工程皮肤的成功构建并应用于临床，标志着皮肤缺损治疗的重大突破。
The successful construction and clinical application of tissue-engineered skin TE skin mark the major breakthrough in treatment of skin defect.
目的：对比研究培养的组织工程皮肤与正常皮肤的角蛋白构型，探讨培养后的表皮分化情况。
AIM: to compare the keratin pattern between the tissue engineered skin and normal skin so as to investigate the differentiation of tissue engineered epidermis.
组织工程化骨与软骨、皮肤、血管等研究也将对骨科创伤修复产生积极影响。
The studies on the tissue engineered-bone, cartilage, skin, and vessels will exert a tremendous impact on the repair of orthopaedic trauma.
结论：以胎儿皮肤为细胞来源、牛i型胶原为支架的全层组织工程皮肤，是一种良好的生物活性皮肤替代物，可用来修复全层皮肤缺损。
Conclusion: Human skin with full thickness can be tissue engineered with foetus back skin as the sources of epithelial cells and fibroblasts, and bovine I type collagen as carrier.
体外培养表皮细胞构建组织工程化人工皮肤是促进皮肤缺损创面愈合、提高创面修复质量的新途径。
Tissue engineered skin constructed by cultured keratinocyte in vitro provides a new way to accelerate skin wound healing and improve the quality of tissue repair.
目的：探讨应用人表皮干细胞和猪脱细胞真皮构建组织工程皮肤修复全层皮肤缺损的可行性。
AIM: to explore the feasibility to repair full-thickness defects with tissue-engineered skin constructed with cultured epidermal stem cells and porcine acellular dermal matrix.
与此同时，最先得到美国食品与药品管理局批准的“组织工程”器官----皮肤----正在美国治愈数以百计的皮肤生疮和皮肤溃疡患者。
Meanwhile , patches of skin , the first"tissue-engineered"organ to be approved by the U. S. Food and Drug Administration , are healing sores and skin ulcers on hundreds of patients across the U. S.
目的利用表皮细胞复合脱细胞真皮构建组织工程皮肤，探讨其用于修复动物皮肤缺损的可行性。
Objective To investigate the feasibility of repairing animal skin defection with tissue-engineered skin made by cultured keratinocytes and acellular dermal matrix.
目的：尝试使用简单的动态种植方法来提高成纤维细胞在三维支架上的种植效率和均匀性，以更有效地构建组织工程皮肤。
Objective:To explore a simple way to improve seeding efficiency and uniformity in constructing 3-D dermal equivalent, in order to effectively construct tissue engineered skin.
目的：尝试使用简单的动态种植方法来提高成纤维细胞在三维支架上的种植效率和均匀性，以更有效地构建组织工程皮肤。
Objective:To explore a simple way to improve seeding efficiency and uniformity in constructing 3-D dermal equivalent, in order to effectively construct tissue engineered skin.
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