于耐受诱导后30 d对受体小鼠作耐受状态的检查，包括供体特异性皮肤移植、混合淋巴细胞反应(MLR)及迟发型超敏反应(DTH)。
Recipient B6 mice were characterized for the tolerance status with donor Lewis rat skin graft, mixed lymphocyte reaction (MLR), and delayed - type hypersensitivity (DTH) assays after 30 days.
结论：环磷酰胺可诱导嵌合免疫耐受的产生，在嵌合状态下可检测到供鼠来源的T细胞。当移植皮肤被排斥时，供鼠来源T细胞占总t细胞的比例显著降低。
Conclusion: Chimerism and immune tolerance can be induced by Cyclophosphmide and when the grafted skin was rejected, the ratio of t cells from BN significantly decreased.
结论：环磷酰胺可诱导嵌合免疫耐受的产生，在嵌合状态下可检测到供鼠来源的T细胞。当移植皮肤被排斥时，供鼠来源T细胞占总t细胞的比例显著降低。
Conclusion: Chimerism and immune tolerance can be induced by Cyclophosphmide and when the grafted skin was rejected, the ratio of t cells from BN significantly decreased.
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