在经皮给药系统中,脂质体是一种极具前途的给药载体。
It was suggested that liposome is a promising carrier for trans dermal drug delivery system.
摘要目的:寻找以聚丙烯酸酯为骨架的睾酮经皮给药系统的最佳处方。
ABSTRACT OBJECTIVE: to search after the optimum formulation of the TDS of testosterone. METHOD: Various formations whose skeleton was polyacrylic acid were designed.
透皮吸收制剂,特别是透皮给药系统是近年来药剂研究的重要课题之一。
The study on percutaneous absorption preparations, especially transdermal therapeutic systems is one of the important topics on medications.
结论采用均匀设计法优选的配方组成符合骨架控释型透皮给药系统的要求。
Conclusion the prescription composition optimized by uniform design meets the requirement of skeleton-controlled transdermal delivery system.
目的:介绍近年来国内外透皮给药的研究进展,以促进透皮给药系统的开发。
Objective:To promote development of transdermal drug delivery system and present the internal and external advancement of recent years.
许多新方法和新技术的应用,使经皮给药系统逐渐成为一种成熟的给药方法。
With utilities of new methods and techniques, TDDS is becoming a mature method.
选择壳聚糖作为透皮给药系统的控释材料,并对壳聚糖的成膜条件进行了研究。
Chitosan was chosen as the controlling materials for the transdermal drug delivery system, and the conditions of preparing chitosan membranes were researched.
结果提示,这种聚乙烯醇凝胶可望作为药物透皮给药系统的一种新的良好载体。
The results show that the PVA gel may be a fine carrier for transdermal therapeutic system.
结果表明,该聚氨酯压敏胶贴剂具有良好的药物控释能力,适用于经皮给药系统。
The results indicated that the hydrophilic polyurethane PSA prepared show good transdermal drug release properties, which suit for the TDDs application.
目的由于皮肤的屏障作用,经皮给药系统的应用受到限制,促透方法的研究成为焦点。
Because of the barrier of skin, the application of transdermal delivery system is limited. It is very important to study enhancement methods of drug percutaneous absorption.
这样,研制适宜的辅料如:载体、促渗材料和骨架材料等成为了研制透皮给药系统的重心。
Therefore, the key problems in the TDDS are the development of proper auxiliary materials such as carriers, enhancers and bone materials.
结论:1,2 -丙二醇,月桂氮卓芯酮—胰岛素传递体经皮给药系统可进一步提高胰岛素传递体的透皮吸收效率,降低血糖。
CONCLUSION Transfersulin system with azone and 1, 2-propanediol can improve the penetration efficiency on mice skin and eliminate the blood glucose.
本文针对经皮给药系统新型压敏胶及新型经皮给药技术需求,研制了三类亲水性压敏胶及两种药物纳米载体材料,并对其性能进行了研究。
In this study, three kinds of hydrophilic pressure sensitive adhesives and two kinds of nanocarrier materials were prepared for technology requirement of TDDS and their properties were investigated.
本文重点介绍了一些新的给药途径和给药系统,例如鼻腔、颊等给药途径以及黏膜给药系统、透皮给药系统、缓控释技术等给药系统的进展。
The effect of buccal mucosa in different regions on penetration and absorption of drugs, various and quality evaluation methods of buccal mucosa drug delivery system are introduced.
药物的初始释放速率和传统经皮给药控释系统相近,释药量与储库层药物含量无关;
The release rate of composite patches was similar to that of traditional patches at the beginning but was larger on average.
结论优化条件制备出的补骨脂素皮肤用纳米粒载药系统有可能成为临床上改进补骨素光化学疗法降低其毒副作用的一种新的经皮给药制剂。
CONCLUSION Psoralen loaded PLGA nanospartilcles might be a promising transdermal delivery system in order to improve the efficacy and reduce the side effects in the PUVA therapy.
本文的目的是对抗疟药青蒿素的经皮给药进行系统设计和确定青蒿素贴剂的制备工艺。
The purpose of this study was to investigate a transdermal delivery system of antimalarial drug: artemisinin.
本文的目的是对抗疟药青蒿素的经皮给药进行系统设计和确定青蒿素贴剂的制备工艺。
The purpose of this study was to investigate a transdermal delivery system of antimalarial drug: artemisinin.
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